Article
Food Science & Technology
Karunrat Sakulnarmrat, Denchai Wongsrikaew, Izabela Konczak
Summary: Red cabbage anthocyanin-rich extract (RCA) was successfully encapsulated with maltodextrin dextrose equivalent 20 (MD20) and arabic gum (AG) at specific ratios, with MD20:AG 20:80 showing the highest encapsulation efficiency and anthocyanin content. The encapsulates exhibited high solubility, low moisture content and water activities. The MD20:AG 20:80 encapsulate was chosen for application in food, improving the shelf-life and antioxidant capacity of a native Thai dessert Aluar.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Polymer Science
Erlin Arda Safitri, I. Putu Mahendra, Anggi Eka Putra, M. Alvien Ghifari, Demi Dama Yanti, Yusnaidar Yusnaidar, Bambang Ariwahjoedi, Jose Alberto Mendez
Summary: By incorporating anthocyanin and lignocellulose nanofiber into poly (ethylene glycol) diacrylate-based hydrogel, colorimetric indicator gels with multicolor response were developed. This gel film indicator can be used as a food freshness indicator focusing on the detection of ammonia and amine compounds.
Article
Food Science & Technology
Olga Mileti, Noemi Baldino, Francesco Filice, Francesca R. Lupi, Maria Stefania Sinicropi, Domenico Gabriele
Summary: This study investigated the extraction process of waste using solvent and supercritical CO2 extraction and utilized the obtained anthocyanins for starch-based food film formulations. The addition of anthocyanins improved the structuring and mechanical properties of the films, making them suitable for applications like dipping using coverage methods. The packaging also exhibited attractiveness and pH-sensitivity.
Article
Horticulture
Okan Erken
Summary: This study found that some bioactive components in red cabbage increase with severe water stress, indicating potential adaptation of red cabbage to drought conditions.
SCIENTIA HORTICULTURAE
(2022)
Article
Food Science & Technology
Shuliang Fang, Zhihao Guan, Cheng Su, Wenshuo Zhang, Jian Zhu, Yuewei Zheng, Houbin Li, Pingping Zhao, Xinghai Liu
Summary: Biosafe colorimetric labels using red cabbage anthocyanin and a neural network were developed to monitor fish freshness. The labels were recognized by smartphones and classified the fish freshness based on the color gradation driven by anthocyanins' response to pH changes. The overall accuracy of the BP neural network prediction reached 92.6%.
Article
Biochemistry & Molecular Biology
Salhah D. Al-Qahtani, Omer A. Azher, Rasha Felaly, Abdu Subaihi, J. Alkabli, Omaymah Alaysuy, Nashwa M. El-Metwaly
Summary: A novel sponge-like biochromic swab was developed by immobilizing a natural anthocyanin probe into microporous cellulose aerogel. The biosensor displays characteristics of simple preparation, environmental-friendliness, biocompatibility, biodegradability, flexibility, portability, and reversibility, showing color changes in response to biochemical changes in sweat. The color change of the anthocyanin probe is pH-dependent, making it suitable for biosensing applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Food Science & Technology
Si Tan, Xin Lan, Shan Chen, Xin Zhong, Wenfeng Li
Summary: Understanding the effects of different processing methods, such as freeze drying, hot air drying, water boiling, steaming, and pickling, on the physical character, total polyphenols, anthocyanin profile, and antioxidant activity of red cabbage is important. The study found that different processing methods resulted in changes in color and texture, and pickling showed the highest values of total polyphenols and DPPH scavenge activity. Water boiling, steaming, and pickling decreased the loss of most anthocyanins in red cabbage compared to drying processes. The study suggested that drying significantly reduced the phytochemical content in red cabbage, and water boiling, steaming, and pickling were recommended methods for daily consumption, with steaming being the best way to retain anthocyanins.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Food Science & Technology
Marcio Augusto Ribeiro Sanches, Callebe Camelo-Silva, Cleberyanne da Silva Carvalho, Jonatan Rafael de Mello, Noadia Genuario Barroso, Eulalia Lopes da Silva Barros, Paula Paulino Silva, Paula Becker Pertuzatti
Summary: This study evaluated the influence of red cabbage extract and sweet whey on the properties of starch films, finding that films with specific formulations have good mechanical properties and antioxidant capacity, suitable for use as packaging materials for ground beef.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Polymer Science
Meng Cheng, Xiaoran Yan, Yingjun Cui, Minjie Han, Yirong Wang, Juan Wang, Rongfei Zhang, Xiangyou Wang
Summary: This study investigated the influence of red cabbage anthocyanin extract on the properties of active packaging films and found that the electrostatic interaction enhanced the stability of anthocyanins in the films and the fastest release rate was observed in distilled water.
Article
Food Science & Technology
Rusandica Stoica, Mihaela Ganciarov, Diana Constantinescu-Aruxandei, Luiza Capra, Ioana-Raluca Suica-Bunghez, Raluca-Madalina Senin, Georgiana Diana Pricope, Georgeta-Ramona Ivan, Costin Calin, Florin Oancea
Summary: This study developed a sustainable process for extracting anthocyanins from red cabbage byproducts using apple vinegar as the extractant. The results showed that a mixture of 50% ethanol-water, acidified with apple vinegar, with a ratio of 25 g red cabbage by-products per 100 mL solvent, was the most effective solvent for preparing a stable anthocyanin extract for food applications.
Article
Engineering, Environmental
Salhah D. Al-Qahtani, Hanan K. Alzahrani, Omer A. Azher, Zeid O. Owidah, Matokah Abualnaja, Turki M. Habeebullah, Nashwa M. El-Metwaly
Summary: A high-sensitivity viscose fabric was developed for colorimetric recognition of urea in fluids using co-encapsulated calcium alginate nanoparticles. Extracted anthocyanin from red-cabbage and urease enzyme were studied for their role in the fabrication of a biosensor on fabrics. The colorimetric changes of the fabric were monitored with increasing urea concentration, showing a shift in absorbance spectra and color variations.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Engineering, Environmental
Mehrez E. El-Naggar, Mohamed H. El-Newehy, Ali Aldalbahi, Waheed M. Salem, Tawfik A. Khattab
Summary: An effective nanofibrous metallochromic sensor mat has been developed, using electrospun nanofibers and anthocyanin extract for detecting ferric ions in water. This sensor shows excellent selectivity, simplicity, and sensitivity compared to other detection techniques, with advantages in environmental safety and ease of operation.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Julie-Anne Fenger, Gregory T. Sigurdson, Rebecca J. Robbins, Thomas M. Collins, M. Monica Giusti, Olivier Dangles
Summary: The study found that anthocyanins from red cabbage and purple sweet potato exhibit different coloring properties with metal ions due to structural differences, and acylation by noncoordinating acyl residues favored metal binding. Kinetic analysis showed the formation of metal-anthocyanin complexes of 1:1, 1:2, and 1:3 stoichiometries.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Daru Seto Bagus Anugrah, Laura Virdy Darmalim, Juan David Sinanu, Rianita Pramitasari, Dionysius Subali, Eko Adi Prasetyanto, Xuan Thang Cao
Summary: In this study, pH-sensitive film indicators for intelligent food packaging were developed by incorporating red cabbage anthocyanins and zinc oxide nanoparticles into an alginate film. The resulting film demonstrated significant improvements in physical, mechanical, and structural properties, as well as heightened sensitivity to pH fluctuations. Visual assessment and colorimetric analysis confirmed the accuracy and reliability of the film in detecting food spoilage. Additionally, the film exhibited antioxidant and antibacterial properties, with no toxic effects on cells.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Omaymah Alaysuy, Razan M. Snari, Alia Abdulaziz Alfi, Afrah M. Aldawsari, Sraa Abu-Melha, Mohamed E. Khalifa, Nashwa M. El-Metwaly
Summary: A novel multifunctional wound dressing utilizing red-cabbage extract was developed, exhibiting antimicrobial, biochromic, and pH-responsive properties. Experimental studies have confirmed its potential application value in wound treatment.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Yu-Ran Lee, Eun Young Bae, Hong Ryang Kil, Byeong-Hwa Jeon, Geena Kim
Summary: This study investigated the association between APE1/Ref-1 and Kawasaki disease (KD). The results showed that APE1/Ref-1 levels were significantly higher in KD patients, especially in refractory KD. APE1/Ref-1 could be a beneficial biomarker for the diagnosis and prognosis of KD.
Article
Biochemistry & Molecular Biology
Su-jeong Choi, Harsha Nagar, Jun Wan Lee, Seonhee Kim, Ikjun Lee, Shuyu Piao, Byeong Hwa Jeon, Cuk-Seong Kim
Summary: This study found that IDH2 deficiency induced increased expression of SDC2 in endothelial cells, with MMP7 and TGF-beta signaling playing regulatory roles. UTI could reverse the increase in SDC2, MMP7, and TGF-beta signaling caused by IDH2 deficiency.
Article
Biochemistry & Molecular Biology
Sunga Choi, Yu-Ran Lee, Ki-Mo Kim, Euna Choi, Byeong-Hwa Jeon
Summary: The regulation of inflammatory signaling in the tumor microenvironment using adenoviral-mediated PPTLS-APE1/Ref-1 can inhibit the activity of inflammatory immune cells and cancer cells, providing a potential therapeutic strategy for treating triple-negative breast cancer.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Thi Minh Nguyet Nguyen, So-Young Ban, Kyu-Been Park, Chang-Kyu Lee, Seoung-Woo Lee, Young-Jin Lee, Su-Min Baek, Jin-Kyu Park, My Tuyen Thi Nguyen, Jaehan Kim, Jihyun Park, Jong-Tae Park
Summary: This study demonstrates the anti-allergic activities of inotodiol from chaga mushroom in vivo by inhibiting mast cell function, without causing any detrimental effect. It highlights the potential use of inotodiol as an immune modulator for diseases related to inflammation.
Article
Biochemistry & Molecular Biology
Sungmin Kim, Yu-Ran Lee, Eun-Ok Lee, Hao Jin, Yeon-Hee Choi, Hee-Kyoung Joo, Byeong-Hwa Jeon
Summary: This study found that dietary capsanthin has anti-inflammatory and anti-vascular inflammation effects on atherosclerotic mice, reducing plaque formation and inflammatory marker levels.
Article
Integrative & Complementary Medicine
Seonhee Kim, Harsha Nagar, Ikjun Lee, Su-Jeong Choi, Shuyu Piao, Byeong Hwa Jeon, Shin Kwang Kang, Hee-Jung Song, Cuk-Seong Kim
Summary: Breast cancer is a common and deadly disease, especially in triple-negative breast cancer (TNBC) cases. This study investigates the potential of sericite, a natural mineral, as an antitumor agent for TNBC. The results show that sericite can inhibit cell proliferation, induce cell cycle arrest, and promote apoptotic cell death. These findings suggest that sericite could be a potential therapeutic option for TNBC.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2022)
Article
Biology
Seonhee Kim, Ikjun Lee, Shuyu Piao, Harsha Nagar, Su-Jeong Choi, Young-Rae Kim, Kaikobad Irani, Byeong Hwa Jeon, Cuk-Seong Kim
Summary: It has been found that miR204 plays a role in promoting the development of non-alcoholic fatty liver disease by regulating hepatic fatty acid metabolism and inflammation.
COMMUNICATIONS BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Eun-Ok Lee, Hee-Kyoung Joo, Yu-Ran Lee, Sungmin Kim, Kwon-Ho Lee, Sang-Do Lee, Byeong-Hwa Jeon
Summary: Apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) is involved in DNA repair and redox regulation. It inhibits adipocyte differentiation by regulating adipogenic transcription factors, suggesting it as a potential therapeutic target for regulating adipocyte differentiation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Shuyu Piao, Ikjun Lee, Seonhee Kim, Hyewon Park, Harsha Nagar, Su-Jeong Choi, Giang-Huong Vu, Minsoo Kim, Eun-Ok Lee, Byeong-Hwa Jeon, Dong Woon Kim, Youngduk Seo, Cuk-Seong Kim
Summary: This study investigates the role of CRIF1 deficiency in modulating mitochondrial oxidative phosphorylation (OXPHOS) system dysfunction and its antitumor effects in MCF-7 breast cancer cells. CRIF1 silencing decreases the assembly of mitochondrial OXPHOS complexes, leading to mitochondrial dysfunction and elevated reactive oxygen species (ROS) levels. Inhibition of CRIF1 suppresses cell proliferation and inhibits cell migration in MCF-7 cells, and intratumoral injection of CRIF1 siRNA nanoparticles inhibits tumor growth in MCF-7 xenograft mice.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Phu Cuong Nguyen, My Tuyen Thi Nguyen, Ba Tai Truong, Dae-Ryeol Kim, Sujin Shin, Ju-Eun Kim, Kyu-Been Park, Ji-Hyun Park, Phuong Lan Tran, So-Young Ban, Jaehan Kim, Jong-Tae Park
Summary: This study aimed to develop an efficient method to produce high-purity inotodiol from Chaga mushroom and evaluate its physicochemical properties and biological activities. A new method with high purity (>97%) and purification yield (33.6%) was developed by optimizing the extraction and purification solvents. Inotodiol exhibited distinctive physicochemical properties compared to cholesterol and lanosterol, and a nonionic surfactant-based microemulsion was developed to improve its bioavailability. The microemulsion showed effectiveness in oral delivery and potential applications in functional food, cosmetic, and pharmaceutical industries.
Article
Biochemistry & Molecular Biology
Ikjun Lee, Shuyu Piao, Seonhee Kim, Harsha Nagar, Su-jeong Choi, Minsoo Kim, Giang-Huong Vu, Byeong-Hwa Jeon, Cuk-Seong Kim
Summary: Endothelial senescence impairs vascular function and is a major factor in age-related vasculature diseases. IDH2 is involved in the production of alpha-ketoglutarate and preservation of mitochondrial function. However, the mechanism and regulation of IDH2 in endothelial senescence have not been fully understood.