Increased expression of TREM2 in peripheral cells from mild cognitive impairment patients who progress into Alzheimer's disease

Higher Peripheral TREM2 mRNA Levels Relate to Cognitive Deficits and Hippocampal Atrophy in Alzheimer’s Disease and Amnestic Mild Cognitive Impairment

(2017) Yi Jayne Tan et al.   JOURNAL OF ALZHEIMERS DISEASE

The Alzheimer’s disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway

(2017) Charlotte Jendresen et al.   Journal of Neuroinflammation

DNA methylation changes at TREM2 intron 1 and TREM2 mRNA expression in patients with Alzheimer's disease

(2017) Yuki Ozaki et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Adenosine A2A Receptor Expression in Peripheral Blood Mononuclear Cells of Patients with Mild Cognitive Impairment

(2017) Beatrice Arosio et al.   JOURNAL OF ALZHEIMERS DISEASE

Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status

(2016) Laura Piccio et al.   ACTA NEUROPATHOLOGICA

Apolipoprotein E genotypes and plasma levels in mild cognitive impairment conversion to Alzheimer's disease: A follow-up study

(2016) Daniela Scarabino et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers

(2016) Marc Suárez‐Calvet et al.   EMBO Molecular Medicine

Gene promoter methylation and expression of Pin1 differ between patients with frontotemporal dementia and Alzheimer's disease

(2016) Evelyn Ferri et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

TREM2 variants: new keys to decipher Alzheimer disease pathogenesis

(2016) Marco Colonna et al.   NATURE REVIEWS NEUROSCIENCE

TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model

(2015) Yaming Wang et al.   CELL

Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)

(2015) Yuka Atagi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Deficiency Attenuates Phagocytic Activities of Microglia and Exacerbates Ischemic Damage in Experimental Stroke

(2015) M. Kawabori et al.   JOURNAL OF NEUROSCIENCE

Mild cognitive impairment: a concept in evolution

(2014) R. C. Petersen et al.   JOURNAL OF INTERNAL MEDICINE

Peripheral Blood Mononuclear Cells as a Laboratory to Study Dementia in the Elderly

(2014) Beatrice Arosio et al.   Biomed Research International

Sequential Proteolytic Processing of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Protein by Ectodomain Shedding and γ-Secretase-dependent Intramembranous Cleavage

(2013) Patrick Wunderlich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Variant TREM2 as Risk Factor for Alzheimer's Disease

(2012) Harald Neumann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulation of Innate Immune Responses in the Central Nervous System

(2011) Jeffrey J. Bajramovic   CNS & Neurological Disorders-Drug Targets

Adrenergic regulation of the innate immune response in common carp (Cyprinus carpio L.)

(2011) Magdalena Chadzinska et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

APOE and Alzheimer disease: a major gene with semi-dominant inheritance

(2011) E Genin et al.   MOLECULAR PSYCHIATRY

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Biomarkers for Alzheimer's disease therapeutic trials

(2010) Harald Hampel et al.   PROGRESS IN NEUROBIOLOGY

Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation

(2008) Laura Piccio et al.   BRAIN

Differences of peripheral inflammatory markers between mild cognitive impairment and Alzheimer's disease

(2008) Paloma Bermejo et al.   IMMUNOLOGY LETTERS