Is Barrett’s-Associated Esophageal Adenocarcinoma a Clonal Disease?

Insights Into the Pathophysiology of Esophageal Adenocarcinoma

(2018) Michael Quante et al.   GASTROENTEROLOGY

Evolution of Barrett’s esophagus through space and time at single-crypt and whole-biopsy levels

(2018) Pierre Martinez et al.   Nature Communications

Dynamic clonal equilibrium and predetermined cancer risk in Barrett’s oesophagus

(2016) Pierre Martinez et al.   Nature Communications

Evolution of oesophageal adenocarcinoma from metaplastic columnar epithelium without goblet cells in Barrett's oesophagus

(2015) Danielle L Lavery et al.   GUT

Paired exome analysis of Barrett's esophagus and adenocarcinoma

(2015) Matthew D Stachler et al.   NATURE GENETICS

Whole-genome sequencing provides new insights into the clonal architecture of Barrett's esophagus and esophageal adenocarcinoma

(2015) Caryn S Ross-Innes et al.   NATURE GENETICS

Comparison of Cancer-Associated Genetic Abnormalities in Columnar-Lined Esophagus Tissues With and Without Goblet Cells

(2014) Santhoshi Bandla et al.   ANNALS OF SURGERY

Barrett oesophagus: lessons on its origins from the lesion itself

(2014) Stuart A. C. McDonald et al.   Nature Reviews Gastroenterology & Hepatology

Quantification of Crypt and Stem Cell Evolution in the Normal and Neoplastic Human Colon

(2014) Ann-Marie Baker et al.   Cell Reports

Temporal and Spatial Evolution of Somatic Chromosomal Alterations: A Case-Cohort Study of Barrett's Esophagus

(2013) X. Li et al.   Cancer Prevention Research

British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus

(2013) Rebecca C Fitzgerald et al.   GUT

Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity

(2013) Austin M Dulak et al.   NATURE GENETICS

Defining Stem Cell Dynamics in Models of Intestinal Tumor Initiation

(2013) L. Vermeulen et al.   SCIENCE

NSAIDs Modulate Clonal Evolution in Barrett's Esophagus

(2013) Rumen L. Kostadinov et al.   PLoS Genetics

American Gastroenterological Association Technical Review on the Management of Barrett's Esophagus

(2011) Stuart J. Spechler et al.   GASTROENTEROLOGY

Barrett's metaplasia glands are clonal, contain multiple stem cells and share a common squamous progenitor

(2011) Anna M Nicholson et al.   GUT

The incidence of oesophageal adenocarcinoma in non-dysplastic Barrett's oesophagus: a meta-analysis

(2011) Tusar K Desai et al.   GUT

Clonality Assessment and Clonal Ordering of Individual Neoplastic Crypts Shows Polyclonality of Colorectal Adenomas

(2010) Christina Thirlwell et al.   GASTROENTEROLOGY

Use of Methylation Patterns to Determine Expansion of Stem Cell Clones in Human Colon Tissue

(2010) Trevor A. Graham et al.   GASTROENTEROLOGY

Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's oesophagus

(2008) S J Leedham et al.   GUT

Cardiac rather than intestinal-type background in endoscopic resection specimens of minute Barrett adenocarcinoma

(2008) Kaiyo Takubo et al.   HUMAN PATHOLOGY

Many different tumor types have polyclonal tumor origin: Evidence and implications

(2008) B PARSONS   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Mechanisms of Field Cancerization in the Human Stomach: The Expansion and Spread of Mutated Gastric Stem Cells

(2007) Stuart A.C. McDonald et al.   GASTROENTEROLOGY