Copper-catalyzed synthesis of α-amino nitriles through methyl transfer from DMF to aromatic amines

Radical C(sp3)–H alkenylation, alkynylation and allylation of ethers and amides enabled by photocatalysis

(2017) Subhasis Paul et al.   GREEN CHEMISTRY

Metal-Free Aerobic Oxidative Cyanation of Tertiary Amines: Azobis(isobutyronitrile) (AIBN) as a Sole Cyanide Source

(2017) Peng-Yu Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Metal-free Cross-Dehydrogenative Coupling of HN-azoles with α-C(sp3)-H Amides via C–H Activation and Its Mechanistic and Application Studies

(2017) Hariprasad Aruri et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Cross-Dehydrogenative N2-Coupling of NH-1,2,3-Triazoles with N,N -Dialkylamides: N-Amidoalkylation of NH-1,2,3-Triazoles

(2017) Xiaocong Deng et al.   JOURNAL OF ORGANIC CHEMISTRY

Photoinduced Nickel-Catalyzed Chemo- and Regioselective Hydroalkylation of Internal Alkynes with Ether and Amide α-Hetero C(sp3)–H Bonds

(2017) Hong-Ping Deng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N,N-Dimethylformamide as a Methylenating Reagent: Synthesis of HeterodiarylmethanesviaCopper-Catalyzed Coupling between Imidazo[1,2-a]pyridines and Indoles/N,N-Dimethylaniline

(2016) Susmita Mondal et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Strained γ-Lactams by Palladium(0)-Catalyzed C(sp3 )−H Alkenylation and Application to Alkaloid Synthesis

(2016) Philipp M. Holstein et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Arylazetidines: Preparation through Anionic Ring Closure

(2016) Pierre Quinodoz et al.   JOURNAL OF ORGANIC CHEMISTRY

Transition Metal-Free Amidoalkylation of Benzothiazoles and Amidoalkylarylation of Activated Alkenes with N,N-Dialkylamides

(2016) Jian Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Photochemical Nickel-Catalyzed C–H Arylation: Synthetic Scope and Mechanistic Investigations

(2016) Drew R. Heitz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Synthesis of Multisubstituted Pyrroles via a Copper-Catalyzed Tandem Three-Component Reaction

(2016) Xue-Qing Mou et al.   ORGANIC LETTERS

A nickel-mediated oxidative α-C(sp3)–H functionalization of amides with allylic alcohols terminated by radical 1,2-aryl migration

(2015) Ren-Jie Song et al.   CHEMICAL COMMUNICATIONS

Cyanoacetic Acid as a Masked Electrophile: Transition-Metal-Free Cyanomethylation of Amines and Carboxylic Acids

(2015) Hongxiang Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Metal-Free Oxidative Functionalization of a C(sp3)–H Bond Adjacent to Nitrogen and Intramolecular Aromatic Cyclization for the Preparation of 6-Amidophenanthridines

(2015) Hong Fang et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-catalyzed dicyanation of N,N-disubstituted formamide

(2015) Xue-Qing Mou et al.   TETRAHEDRON LETTERS

Direct oxidative cyanation of tertiary amines promoted by in situ generated hypervalent iodine(III)-CN intermediate

(2015) Hang Shen et al.   TETRAHEDRON LETTERS

Perfluorobutyl iodide-assisted direct cyanomethylation of azoles and phenols with acetonitrile

(2015) Juan Zhang et al.   RSC Advances

Copper-catalysed oxidative Csp3–H methylenation to terminal olefins using DMF

(2014) Jianming Liu et al.   CHEMICAL COMMUNICATIONS

Heterocycles from α-Aminonitriles

(2014) Nicola Otto et al.   CHEMISTRY-A EUROPEAN JOURNAL

Functionalization of Amides via Copper-Catalyzed Oxyalkylation of Vinylarenes and Decarboxylative Alkenylation of sp3 C–H

(2014) Hong Yan et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalyst-Free Approach to Construct C–C Bond Initiated by N–O Bond Cleavage under Thermal Conditions

(2014) Dan-Dan Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Base-promoted dehydrogenative coupling of benzene derivatives with amides or ethers

(2014) Ryota Ueno et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Predictably Selective (sp3)C–O Bond Formation through Copper Catalyzed Dehydrogenative Coupling: Facile Synthesis of Dihydro-oxazinone Derivatives

(2014) Atanu Modak et al.   ORGANIC LETTERS

Nucleophilic Attack of α-Aminoalkyl Radicals on CarbonNitrogen Triple Bonds to Construct α-Amino Nitriles: An Experimental and Computational Study

(2013) Chao Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhenium-Catalyzed Oxidative Cyanation of Tertiary Amines with TMSCN

(2013) Aijun Lin et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

DMF as Carbon Source: Rh-Catalyzed α-Methylation of Ketones

(2013) Yang Li et al.   ORGANIC LETTERS

A Versatile C–H Functionalization of Tetrahydroisoquinolines Catalyzed by Iodine at Aerobic Conditions†

(2013) Jayaraman Dhineshkumar et al.   ORGANIC LETTERS

Metal-Free Oxidative C(sp3)–H Bond Thiolation of Ethers with Disulfides

(2013) Sheng-rong Guo et al.   ORGANIC LETTERS

Cobalt-Catalyzed Oxidative α-Cyanation of Tertiary Aromatic Amines with Trimethylsilyl Cyanide and tert-Butyl Hydroperoxide

(2013) Norio Sakai et al.   SYNLETT

Oxidative Cyanation of Tertiary Amines with Ethyl Cyanoformate over a Niobia-Supported Iron-Exchanged Molybdophosphoric Acid Catalyst

(2012) Kasanneni Tirumala Venkateswara Rao et al.   ChemCatChem

Photoredox functionalization of C–H bonds adjacent to a nitrogen atom

(2012) Lei Shi et al.   CHEMICAL SOCIETY REVIEWS

Light-Mediated Heterogeneous Cross Dehydrogenative Coupling Reactions: Metal Oxides as Efficient, Recyclable, Photoredox Catalysts in CC Bond-Forming Reactions

(2012) Magnus Rueping et al.   CHEMISTRY-A EUROPEAN JOURNAL

Iron-Catalyzed N-Alkylation of Azoles via Cleavage of an sp3 C–H Bond Adjacent to a Nitrogen Atom

(2012) Qinqin Xia et al.   JOURNAL OF ORGANIC CHEMISTRY

Friedel–Crafts Amidoalkylation via Thermolysis and Oxidative Photocatalysis

(2012) Chunhui Dai et al.   JOURNAL OF ORGANIC CHEMISTRY

Rh-Catalyzed Borylation of N-Adjacent C(sp3)–H Bonds with a Silica-Supported Triarylphosphine Ligand

(2012) Soichiro Kawamorita et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Comparative Mechanistic Study of Cu-Catalyzed Oxidative Coupling Reactions with N-Phenyltetrahydroisoquinoline

(2012) Esther Boess et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

KI-catalyzed imidation of sp3 C–H bond adjacent to amide nitrogen atom

(2012) Zhi-Qi Lao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Azobisisobutyronitrile Initiated Aerobic Oxidative Transformation of Amines: Coupling of Primary Amines and Cyanation of Tertiary Amines

(2012) Lianghui Liu et al.   ORGANIC LETTERS

Recyclable Ru/C catalyzed oxidative cyanation of tertiary amines with TBHP

(2012) K. Harsha Vardhan Reddy et al.   RSC Advances

Acetone Cyanohydrin: A Convenient Alternative of Toxic Sodium Cyanide/Acetic Acid for Oxidative Cyanation of Tertiary Amines

(2011) Sanny Verma et al.   CATALYSIS LETTERS

Visible-light photoredox catalyzed oxidative Strecker reaction

(2011) Magnus Rueping et al.   CHEMICAL COMMUNICATIONS

Asymmetric Strecker Reactions

(2011) Jun Wang et al.   CHEMICAL REVIEWS

Graphene oxide and Rose Bengal: oxidative C–H functionalisation of tertiary amines using visible light

(2011) Yuanhang Pan et al.   GREEN CHEMISTRY

Tropylium Ion Mediated α-Cyanation of Amines

(2011) Julia M. Allen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C–H functionalization of tertiary amines by cross dehydrogenative coupling reactions: solvent-free synthesis of α-aminonitriles and β-nitroamines under aerobic condition

(2011) Kaliyamoorthy Alagiri et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Eosin Y Catalyzed Visible Light Oxidative C–C and C–P bond Formation

(2011) Durga Prasad Hari et al.   ORGANIC LETTERS

Efficient Synthesis of Hydroxytyrosol from 3,4-Dihydroxybenzaldehyde

(2011) Zhao-Li Zhang et al.   SYNTHETIC COMMUNICATIONS

Iron oligopyridine complexes as efficient catalysts for practical oxidation of arenes, alkanes, tertiary amines and N-acyl cyclic amines with Oxone

(2011) Peng Liu et al.   Chemical Science

Heterogeneously Catalyzed Oxidative Cyanation of Tertiary Amines with Sodium Cyanide/Hydrogen Peroxide using Polymer-Supported Iron(II) Phthalocyanines as Catalyst

(2010) Sweety Singhal et al.   ADVANCED SYNTHESIS & CATALYSIS

Gold-complexes catalyzed oxidative α-cyanation of tertiary amines

(2010) Yan Zhang et al.   CHEMICAL COMMUNICATIONS

Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore

(2010) Fraser F. Fleming et al.   JOURNAL OF MEDICINAL CHEMISTRY

Iron-Catalyzed Oxidative Coupling of Alkylamides with Arenes through Oxidation of Alkylamides Followed by Friedel−Crafts Alkylation

(2010) Eiji Shirakawa et al.   JOURNAL OF ORGANIC CHEMISTRY

Investigation of the Mechanism of C(sp3)−H Bond Cleavage in Pd(0)-Catalyzed Intramolecular Alkane Arylation Adjacent to Amides and Sulfonamides

(2010) Sophie Rousseaux et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron catalyzed oxidative cyanation of tertiary amines

(2009) Wei Han et al.   CHEMICAL COMMUNICATIONS

An efficient aerobic oxidative cyanation of tertiary amines with sodium cyanide using vanadium based systems as catalysts

(2009) Sweety Singhal et al.   CHEMICAL COMMUNICATIONS

N-(Anilinoethyl)amides: Design and Synthesis of Metabolically Stable, Selective Melatonin Receptor Ligands

(2009) Silvia Rivara et al.   ChemMedChem

Development of potent and selective small-molecule human Urotensin-II antagonists

(2008) John J. McAtee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Ruthenium catalyzed biomimetic oxidation in organic synthesis inspired by cytochrome P-450

(2008) Shun-Ichi Murahashi et al.   CHEMICAL SOCIETY REVIEWS

Ruthenium-Catalyzed Oxidative Cyanation of Tertiary Amines with Molecular Oxygen or Hydrogen Peroxide and Sodium Cyanide: sp3C−H Bond Activation and Carbon−Carbon Bond Formation

(2008) Shun-Ichi Murahashi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalyzed Strecker reactions

(2008) Pedro Merino et al.   TETRAHEDRON