Roles of autophagy in controlling stem cell identity: a perspective of self-renewal and differentiation

Phosphorylation of ULK1 by AMPK is essential for mouse embryonic stem cell self-renewal and pluripotency

(2018) Jiaqi Gong et al.   Cell Death & Disease

Phosphorylation of p62 by AMP-activated protein kinase mediates autophagic cell death in adult hippocampal neural stem cells

(2017) Shinwon Ha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of Parkinson’s disease-related proteins in mediating secondary brain damage after cerebral ischemia

(2017) TaeHee Kim et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Quantitative proteomics reveals EVA1A-related proteins involved in neuronal differentiation

(2017) Lijun Zhong et al.   PROTEOMICS

Autophagy regulates the apoptosis of bone marrow-derived mesenchymal stem cells under hypoxic condition via AMP-activated protein kinase/mammalian target of rapamycin pathway

(2016) Zheng Zhang et al.   CELL BIOLOGY INTERNATIONAL

Mammalian Target of Rapamycin: Its Role in Early Neural Development and in Adult and Aged Brain Function

(2016) Carla Garza-Lombó et al.   Frontiers in Cellular Neuroscience

Rapamycin regulates autophagy and cell adhesion in induced pluripotent stem cells

(2016) Areechun Sotthibundhu et al.   Stem Cell Research & Therapy

Autophagy in stem and progenitor cells

(2015) Carlo Rodolfo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Expression of a novel serine/threonine kinase gene, Ulk4, in neural progenitors during Xenopus laevis forebrain development

(2015) L. Domínguez et al.   NEUROSCIENCE

Rapamycin alleviates cisplatin-induced ototoxicity in vivo

(2014) Bin Fang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Environmental enrichment enhances autophagy signaling in the rat hippocampus

(2014) Tomohisa Takahashi et al.   BRAIN RESEARCH

Atomistic Autophagy: The Structures of Cellular Self-Digestion

(2014) James H. Hurley et al.   CELL

mTOR regulates brain morphogenesis by mediating GSK3 signaling

(2014) M. Ka et al.   DEVELOPMENT

Nrbf2 Protein Suppresses Autophagy by Modulating Atg14L Protein-containing Beclin 1-Vps34 Complex Architecture and Reducing Intracellular Phosphatidylinositol-3 Phosphate Levels

(2014) Yu Zhong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurogenesis in the embryonic and adult brain: same regulators, different roles

(2014) Noelia Urbán et al.   Frontiers in Cellular Neuroscience

The autophagy regulators Ambra1 and Beclin 1 are required for adult neurogenesis in the brain subventricular zone

(2014) M Yazdankhah et al.   Cell Death & Disease

Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2

(2013) Fiona McAlpine et al.   Autophagy

Interplay between autophagy and programmed cell death in mammalian neural stem cells

(2013) Kyung Min Chung et al.   BMB Reports

Dynamics of Hippocampal Neurogenesis in Adult Humans

(2013) Kirsty L. Spalding et al.   CELL

Transient Activation of Autophagy via Sox2-Mediated Suppression of mTOR Is an Important Early Step in Reprogramming to Pluripotency

(2013) Shuo Wang et al.   Cell Stem Cell

Autophagic control of cell ‘stemness’

(2013) Huize Pan et al.   EMBO Molecular Medicine

Autophagy Induced by the Withdrawal of Mitogens Promotes Neurite Extension in Rat Neural Stem Cells

(2013) Ye Chen et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Pharmacological inhibition of the mTOR pathway impairs hippocampal development in mice

(2013) Lakshmi Raman et al.   NEUROSCIENCE LETTERS

Thyroid hormone-dependent development of early cortical networks: temporal specificity and the contribution of trkB and mTOR pathways

(2013) Sören Westerholz et al.   Frontiers in Cellular Neuroscience

Atg5 and Ambra1 differentially modulate neurogenesis in neural stem cells

(2012) Patricia Vázquez et al.   Autophagy

Modification of hippocampal circuitry by adult neurogenesis

(2012) Juan Song et al.   Developmental Neurobiology

The Age of Olfactory Bulb Neurons in Humans

(2012) Olaf Bergmann et al.   NEURON

An Elaborate Regulation of Mammalian Target of Rapamycin Activity Is Required for Somatic Cell Reprogramming Induced by Defined Transcription Factors

(2012) Jing He et al.   STEM CELLS AND DEVELOPMENT

Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells

(2011) Taotao Chen et al.   AGING CELL

A comprehensive glossary of autophagy-related molecules and processes (2ndedition)

(2011) Daniel J Klionsky et al.   Autophagy

The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy

(2011) Eun-Ju Lee et al.   Autophagy

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: A roadmap from energy metabolism to stem cell renewal and aging

(2011) Javier A. Menendez et al.   CELL CYCLE

Autophagy is required for self-renewal and differentiation of adult human stem cells

(2011) Souzan Salemi et al.   CELL RESEARCH

Long-term treadmill exercise induces neuroprotective molecular changes in rat brain

(2011) S. Bayod et al.   JOURNAL OF APPLIED PHYSIOLOGY

NOTCH and phosphatidylinositide 3-kinase/phosphatase and tensin homolog deleted on chromosome ten/AKT/mammalian target of rapamycin (mTOR) signaling in T-cell development and T-cell acute lymphoblastic leukemia

(2011) Dongmei Guo et al.   LEUKEMIA & LYMPHOMA

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Inhibition of the mammalian target of rapamycin promotes cyclic AMP-induced differentiation of NG108-15 cells

(2010) Ting-Yu Chin et al.   Autophagy

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

(2010) Eisuke Itakura et al.   Autophagy

A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic

(2010) Sigrid B. Thoresen et al.   EXPERIMENTAL CELL RESEARCH

Autophagy in human keratinocytes: an early step of the differentiation?

(2010) Elodie Aymard et al.   EXPERIMENTAL DERMATOLOGY

Dual Function of UNC-51-like Kinase 3 (Ulk3) in the Sonic Hedgehog Signaling Pathway

(2010) Alla Maloverjan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Autophagy impairment inhibits differentiation of glioma stem/progenitor cells

(2009) Yaodong Zhao et al.   BRAIN RESEARCH

Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube

(2009) Katherine J. Fishwick et al.   DEVELOPMENTAL BIOLOGY

Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathway

(2009) Alla Maloverjan et al.   EXPERIMENTAL CELL RESEARCH

Atg17 recruits Atg9 to organize the pre-autophagosomal structure

(2009) Takayuki Sekito et al.   GENES TO CELLS

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex

(2009) Yun Zhong et al.   NATURE CELL BIOLOGY

DISC1 Regulates New Neuron Development in the Adult Brain via Modulation of AKT-mTOR Signaling through KIAA1212

(2009) Ju Young Kim et al.   NEURON

mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells

(2009) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms and Functional Implications of Adult Neurogenesis

(2008) Chunmei Zhao et al.   CELL

Roles of autophagy and mTOR signaling in neuronal differentiation of mouse neuroblastoma cells

(2007) Mei Zeng et al.   CELLULAR SIGNALLING