Autophagic control of cell ‘stemness’

Generation of induced pluripotent stem cell lines from 3 distinct laminopathies bearing heterogeneous mutations in lamin A/C

(2016) Jenny CY Ho et al.   Aging-US

Mitochondrial fusion by pharmacological manipulation impedes somatic cell reprogramming to pluripotency: New insight into the role of mitophagy in cell stemness

(2016) Alejandro Vazquez-Martin et al.   Aging-US

The fibroblast growth factor signaling axis controls cardiac stem cell differentiation through regulating autophagy

(2012) Jue Zhang et al.   Autophagy

Atg5 and Ambra1 differentially modulate neurogenesis in neural stem cells

(2012) Patricia Vázquez et al.   Autophagy

Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells

(2012) Brahma N. Singh et al.   BIOCHEMICAL PHARMACOLOGY

Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease

(2012) Adriana Sánchez-Danés et al.   EMBO Molecular Medicine

Increased SCF/c-kit by hypoxia promotes autophagy of human placental chorionic plate-derived mesenchymal stem cells via regulating the phosphorylation of mTOR

(2012) Youjin Lee et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Protein homeostasis and aging: Role of ubiquitin protein ligases

(2012) Nihar Ranjan Jana   NEUROCHEMISTRY INTERNATIONAL

Basal Autophagy Decreased During the Differentiation of Human Adult Mesenchymal Stem Cells

(2012) Lisa Oliver et al.   STEM CELLS AND DEVELOPMENT

Autophagy Activation: A Novel Mechanism of Atorvastatin to Protect Mesenchymal Stem Cells from Hypoxia and Serum Deprivation via AMP-Activated Protein Kinase/Mammalian Target of Rapamycin Pathway

(2012) Qian Zhang et al.   STEM CELLS AND DEVELOPMENT

Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells

(2011) Taotao Chen et al.   AGING CELL

Lack of autophagy in the hematopoietic system leads to loss of hematopoietic stem cell function and dysregulated myeloid proliferation

(2011) Monika Mortensen et al.   Autophagy

The Parkinson disease protein α-synuclein inhibits autophagy

(2011) Ashley R. Winslow et al.   Autophagy

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: A roadmap from energy metabolism to stem cell renewal and aging

(2011) Javier A. Menendez et al.   CELL CYCLE

Autophagy is required for self-renewal and differentiation of adult human stem cells

(2011) Souzan Salemi et al.   CELL RESEARCH

Autophagy: for better or for worse

(2011) Ellen Wirawan et al.   CELL RESEARCH

Targeted Gene Correction of Laminopathy-Associated LMNA Mutations in Patient-Specific iPSCs

(2011) Guang-Hui Liu et al.   Cell Stem Cell

FRS2α-Mediated FGF Signals Suppress Premature Differentiation of Cardiac Stem Cells Through Regulating Autophagy Activity

(2011) Jue Zhang et al.   CIRCULATION RESEARCH

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

(2011) Monika Mortensen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome

(2011) Guang-Hui Liu et al.   NATURE

Control of autophagy as a therapy for neurodegenerative disease

(2011) Harry Harris et al.   Nature Reviews Neurology

Autophagy in Human Embryonic Stem Cells

(2011) Thien Tra et al.   PLoS One

Rapamycin Reverses Cellular Phenotypes and Enhances Mutant Protein Clearance in Hutchinson-Gilford Progeria Syndrome Cells

(2011) K. Cao et al.   Science Translational Medicine

Autophagy in Stem Cell Maintenance and Differentiation

(2011) Alexandre Teixeira Vessoni et al.   STEM CELLS AND DEVELOPMENT

FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells

(2010) F. Liu et al.   BLOOD

A Human iPSC Model of Hutchinson Gilford Progeria Reveals Vascular Smooth Muscle and Mesenchymal Stem Cell Defects

(2010) Jinqiu Zhang et al.   Cell Stem Cell

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Human Induced Pluripotent Stem Cell Lines Show Stress Defense Mechanisms and Mitochondrial Regulation Similar to Those of Human Embryonic Stem Cells

(2010) Lyle Armstrong et al.   STEM CELLS

Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo

(2009) M. Mortensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA