Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells

Reprogramming of Human Primary Somatic Cells by OCT4 and Chemical Compounds

(2010) Saiyong Zhu et al.   Cell Stem Cell

Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells

(2010) Miguel Angel Esteban et al.   Cell Stem Cell

A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts

(2010) Ronghui Li et al.   Cell Stem Cell

Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming

(2010) Payman Samavarchi-Tehrani et al.   Cell Stem Cell

Butyrate Promotes Induced Pluripotent Stem Cell Generation

(2010) Gaoyang Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Butyrate Greatly Enhances Derivation of Human Induced Pluripotent Stem Cells by Promoting Epigenetic Remodeling and the Expression of Pluripotency-Associated Genes

(2010) Prashant Mali et al.   STEM CELLS

mTOR Mediates Wnt-Induced Epidermal Stem Cell Exhaustion and Aging

(2009) Rogerio M. Castilho et al.   Cell Stem Cell

Molecules that Promote or Enhance Reprogramming of Somatic Cells to Induced Pluripotent Stem Cells

(2009) Bo Feng et al.   Cell Stem Cell

A Small-Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog

(2009) Justin K. Ichida et al.   Cell Stem Cell

Tgfβ Signal Inhibition Cooperates in the Induction of iPSCs and Replaces Sox2 and cMyc

(2009) Nimet Maherali et al.   CURRENT BIOLOGY

Senescence impairs successful reprogramming to pluripotent stem cells

(2009) A. Banito et al.   GENES & DEVELOPMENT

The Ink4/Arf locus is a barrier for iPS cell reprogramming

(2009) Han Li et al.   NATURE

mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells

(2009) C. Chen et al.   Science Signaling

A Combined Chemical and Genetic Approach for the Generation of Induced Pluripotent Stem Cells

(2008) Yan Shi et al.   Cell Stem Cell

Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Oct4 and Klf4 with Small-Molecule Compounds

(2008) Yan Shi et al.   Cell Stem Cell

Dissecting direct reprogramming through integrative genomic analysis

(2008) Tarjei S. Mikkelsen et al.   NATURE

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

(2008) Danwei Huangfu et al.   NATURE BIOTECHNOLOGY

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

(2008) Danwei Huangfu et al.   NATURE BIOTECHNOLOGY

Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases

(2008) Beth Apsel et al.   Nature Chemical Biology

Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition

(2008) Jose Silva et al.   PLOS BIOLOGY