Tauroursodeoxycholic acid inhibits intestinal inflammation and barrier disruption in mice with non-alcoholic fatty liver disease

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

(2016) Khalidur Rahman et al.   GASTROENTEROLOGY

Noninvasive imaging methods to determine severity of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

(2016) William N. Hannah et al.   HEPATOLOGY

Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives

(2016) Juan P. Arab et al.   HEPATOLOGY

The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota

(2016) Jérôme Boursier et al.   HEPATOLOGY

Obeticholic acid reduces bacterial translocation and inhibits intestinal inflammation in cirrhotic rats

(2016) María Úbeda et al.   JOURNAL OF HEPATOLOGY

Non-alcoholic fatty liver disease and risk of incident cardiovascular disease: A meta-analysis

(2016) Giovanni Targher et al.   JOURNAL OF HEPATOLOGY

The role of the gut microbiota in NAFLD

(2016) Christopher Leung et al.   Nature Reviews Gastroenterology & Hepatology

Experimental design and analysis and their reporting: new guidance for publication in BJP

(2015) Michael J Curtis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP

(2015) John C McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Akkermansia muciniphilaand improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology

(2015) Maria Carlota Dao et al.   GUT

Identification of an anti-inflammatory protein fromFaecalibacterium prausnitzii, a commensal bacterium deficient in Crohn’s disease

(2015) E Quévrain et al.   GUT

Dysbiosis-induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in mice

(2015) Peng Chen et al.   HEPATOLOGY

Current efforts and trends in the treatment of NASH

(2015) Vlad Ratziu et al.   JOURNAL OF HEPATOLOGY

Primary biliary cirrhosis

(2015) Elizabeth J Carey et al.   LANCET

The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands

(2015) Christopher Southan et al.   NUCLEIC ACIDS RESEARCH

Ruminococcus gnavus: An unusual pathogen in septic arthritis

(2014) Marie Titécat et al.   ANAEROBE

Altering the Intestinal Microbiota during a Critical Developmental Window Has Lasting Metabolic Consequences

(2014) Laura M. Cox et al.   CELL

Endoplasmic reticulum stress does not contribute to steatohepatitis in obese and insulin-resistant high-fat-diet-fedfoz/fozmice

(2014) Vanessa Legry et al.   CLINICAL SCIENCE

Tauroursodeoxycholic Acid Attenuates Progression of Steatohepatitis in Mice Fed a Methionine–Choline-Deficient Diet

(2014) Eun-Ju Cho et al.   DIGESTIVE DISEASES AND SCIENCES

Gut-adipose tissue axis in hepatic fat accumulation in humans

(2014) Eveliina Munukka et al.   JOURNAL OF HEPATOLOGY

Uric acid induces fat accumulation via generation of endoplasmic reticulum stress and SREBP-1c activation in hepatocytes

(2014) Yea-Jin Choi et al.   LABORATORY INVESTIGATION

Interplay between intestinal alkaline phosphatase, diet, gut microbes and immunity

(2014) Mehrbod Estaki   WORLD JOURNAL OF GASTROENTEROLOGY

Genetically obese mice do not show increased gut permeability or faecal bile acid hydrophobicity

(2013) Lotta K. Stenman et al.   BRITISH JOURNAL OF NUTRITION

The Unfolded Protein Response and Chemical Chaperones Reduce Protein Misfolding and Colitis in Mice

(2013) Stewart Siyan Cao et al.   GASTROENTEROLOGY

Dysbiosis contributes to fibrogenesis in the course of chronic liver injury in mice

(2013) Samuele De Minicis et al.   HEPATOLOGY

The Mucin Muc2 Limits Pathogen Burdens and Epithelial Barrier Dysfunction during Salmonella enterica Serovar Typhimurium Colitis

(2013) Maryam Zarepour et al.   INFECTION AND IMMUNITY

Hepatic menin recruits SIRT1 to control liver steatosis through histone deacetylation

(2013) Yanan Cao et al.   JOURNAL OF HEPATOLOGY

A population-based study on the prevalence of NASH using scores validated against liver histology

(2013) Jenni Hyysalo et al.   JOURNAL OF HEPATOLOGY

Disruption of the intestinal mucosal barrier in Candida albicans infections

(2013) Lei Yan et al.   MICROBIOLOGICAL RESEARCH

The Bile Acid Sensor FXR Is Required for Immune-Regulatory Activities of TLR-9 in Intestinal Inflammation

(2013) Barbara Renga et al.   PLoS One

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transient inflammatory-like state and microbial dysbiosis are pivotal in establishment of mucosal homeostasis during colonisation of germ-free mice

(2013) S. El Aidy et al.   Beneficial Microbes

Microbiota Regulate Intestinal Absorption and Metabolism of Fatty Acids in the Zebrafish

(2012) Ivana Semova et al.   Cell Host & Microbe

Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice

(2012) Tiphaine Le Roy et al.   GUT

Dose-dependent antiinflammatory effect of ursodeoxycholic acid in experimental colitis

(2012) Patricia Martínez-Moya et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

(2012) Jorge Henao-Mejia et al.   NATURE

Role of the Gut in Lipid Homeostasis

(2012) Nada A. Abumrad et al.   PHYSIOLOGICAL REVIEWS

High Fat Diet-Induced Gut Microbiota Exacerbates Inflammation and Obesity in Mice via the TLR4 Signaling Pathway

(2012) Kyung-Ah Kim et al.   PLoS One

Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, acinar cell damage, and systemic inflammation in acute pancreatitis

(2011) Ersin Seyhun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Structure–function analysis of the tertiary bile acid TUDCA for the resolution of endoplasmic reticulum stress in intestinal epithelial cells

(2011) Emanuel Berger et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Enterococcus faecalis Metalloprotease Compromises Epithelial Barrier and Contributes to Intestinal Inflammation

(2011) Natalie Steck et al.   GASTROENTEROLOGY

Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells

(2011) Timea Csak et al.   HEPATOLOGY

Interleukin-6 stimulates epithelial sodium channels in mouse cortical collecting duct cells

(2010) Ke Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Gut Microbiota, Lipopolysaccharides, and Innate Immunity in the Pathogenesis of Obesity and Cardiovascular Risk

(2010) Melania Manco et al.   ENDOCRINE REVIEWS

Ironing out the wrinkles in the rare biosphere through improved OTU clustering

(2010) Susan M. Huse et al.   ENVIRONMENTAL MICROBIOLOGY

Enteric dysbiosis associated with a mouse model of alcoholic liver disease

(2010) Arthur W. Yan et al.   HEPATOLOGY

The role of the gut microbiota in nonalcoholic fatty liver disease

(2010) Ahmed Abu-Shanab et al.   Nature Reviews Gastroenterology & Hepatology

Changes in Hepatic Gene Expression upon Oral Administration of Taurine-Conjugated Ursodeoxycholic Acid in ob/ob Mice

(2010) Jae-Seong Yang et al.   PLoS One

Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa

(2010) Kirk S. B. Bergstrom et al.   PLoS Pathogens

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease

(2009) Luca Miele et al.   HEPATOLOGY

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL