Role of the nucleotide-binding domain-like receptor protein 3 inflammasome in acute kidney injury

Simultaneous Targeting of IL-1 and IL-18 Is Required for Protection against Inflammatory and Septic Shock

(2014) Tom Vanden Berghe et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sepsis-induced acute kidney injury revisited

(2014) Alexander Zarbock et al.   Current Opinion in Critical Care

NLRP3 Inflammasome Mediates Albumin-induced Renal Tubular Injury through Impaired Mitochondrial Function

(2014) Yibo Zhuang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pattern recognition receptors and the inflammasome in kidney disease

(2014) Jaklien C. Leemans et al.   Nature Reviews Nephrology

Canonical and non-canonical effects of the NLRP3 inflammasome in kidney inflammation and fibrosis

(2013) Georg Lorenz et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Severe Sepsis and Septic Shock

(2013) Derek C. Angus et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury

(2011) Joseph H. Holthoff et al.   KIDNEY INTERNATIONAL

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Molecular Mechanism of NLRP3 Inflammasome Activation

(2010) Chengcheng Jin et al.   JOURNAL OF CLINICAL IMMUNOLOGY

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

(2010) Irving C. Allen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An Inflammasome-Independent Role for Epithelial-Expressed Nlrp3 in Renal Ischemia-Reperfusion Injury

(2010) A. A. Shigeoka et al.   JOURNAL OF IMMUNOLOGY

Toll-Like Receptors and Danger Signaling in Kidney Injury

(2010) H.-J. Anders   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NF- B in Renal Inflammation

(2010) A. B. Sanz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The NLRP3 Inflammasome Promotes Renal Inflammation and Contributes to CKD

(2010) A. Vilaysane et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mediators of Inflammation in Acute Kidney Injury

(2010) Ali Akcay et al.   MEDIATORS OF INFLAMMATION

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

The NLRP3 Inflammasome: A Sensor for Metabolic Danger?

(2010) K. Schroder et al.   SCIENCE

Modulation of the renin–angiotensin–aldosterone system in sepsis: a new therapeutic approach?

(2009) Diamantino Ribeiro Salgado et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Immunodesign of experimental sepsis by cecal ligation and puncture

(2009) Daniel Rittirsch et al.   Nature Protocols

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

(2009) S. S. Iyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms involved in inflammasome activation

(2009) Clare Bryant et al.   TRENDS IN CELL BIOLOGY

TLR4 Signaling Mediates Inflammation and Tissue Injury in Nephrotoxicity

(2008) B. Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TLR4 Links Podocytes with the Innate Immune System to Mediate Glomerular Injury

(2008) M. C. Banas et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

AP214, an analogue of α-melanocyte-stimulating hormone, ameliorates sepsis-induced acute kidney injury and mortality

(2008) K. Doi et al.   KIDNEY INTERNATIONAL