Vesicular trafficking mechanisms in endothelial cells as modulators of the tumor vasculature and targets of antiangiogenic therapies

Autophagy in malignant transformation and cancer progression

(2015) L. Galluzzi et al.   EMBO JOURNAL

Investigation of the Lack of Angiogenesis in the Formation of Lymph Node Metastases

(2015) Han-Sin Jeong et al.   JNCI-Journal of the National Cancer Institute

VEGFR3 does not sustain retinal angiogenesis without VEGFR2

(2015) Georgia Zarkada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How to control self-digestion: transcriptional, post-transcriptional, and post-translational regulation of autophagy

(2015) Yuchen Feng et al.   TRENDS IN CELL BIOLOGY

Intertwined regulation of angiogenesis and immunity by myeloid cells

(2015) Lee B. Rivera et al.   TRENDS IN IMMUNOLOGY

Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch

(2015) Irene Maria Aspalter et al.   Nature Communications

Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer

(2015) Nicolas Bovy et al.   Oncotarget

Investigation of the Lack of Angiogenesis in the Formation of Lymph Node Metastases

(2015) Han-Sin Jeong et al.   JNCI-Journal of the National Cancer Institute

AIP1 Mediates Vascular Endothelial Cell Growth Factor Receptor-3–Dependent Angiogenic and Lymphangiogenic Responses

(2014) Huanjiao Jenny Zhou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Pressing the right buttons: signaling in lymphangiogenesis

(2014) S. Coso et al.   BLOOD

Tumor Vessel Normalization by Chloroquine Independent of Autophagy

(2014) Hannelore Maes et al.   CANCER CELL

NRP1 Presented in trans to the Endothelium Arrests VEGFR2 Endocytosis, Preventing Angiogenic Signaling and Tumor Initiation

(2014) Sina Koch et al.   DEVELOPMENTAL CELL

Endorepellin Evokes Autophagy in Endothelial Cells

(2014) Chiara Poluzzi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Angiogenesis revisited – role and therapeutic potential of targeting endothelial metabolism

(2014) Peter Stapor et al.   JOURNAL OF CELL SCIENCE

Lymphangiogenic factors, mechanisms, and applications

(2014) Wei Zheng et al.   JOURNAL OF CLINICAL INVESTIGATION

High-mobility group box-1 and its role in angiogenesis

(2014) S. Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Endocytic Accessory Factors and Regulation of Clathrin-Mediated Endocytosis

(2014) C. J. Merrifield et al.   Cold Spring Harbor Perspectives in Biology

How to Take Autophagy and Endocytosis Up a Notch

(2014) Julia M. I. Barth et al.   Biomed Research International

Enhanced autophagy blocks angiogenesis via degradation of gastrin-releasing peptide in neuroblastoma cells

(2013) Kwang Woon Kim et al.   Autophagy

Vascular Normalization as an Emerging Strategy to Enhance Cancer Immunotherapy

(2013) Y. Huang et al.   CANCER RESEARCH

Diverse Autophagosome Membrane Sources Coalesce in Recycling Endosomes

(2013) Claudia Puri et al.   CELL

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

Mitochondria and Endothelial Function

(2013) Matthew A. Kluge et al.   CIRCULATION RESEARCH

Intercellular Communication by Exosome-Derived microRNAs in Cancer

(2013) Bethany Hannafon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer

(2013) Jonathan Welti et al.   JOURNAL OF CLINICAL INVESTIGATION

VEGFA and tumour angiogenesis

(2013) L. Claesson-Welsh et al.   JOURNAL OF INTERNAL MEDICINE

Spatial regulation of VEGF receptor endocytosis in angiogenesis

(2013) Masanori Nakayama et al.   NATURE CELL BIOLOGY

Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor

(2013) Takehiro Torisu et al.   NATURE MEDICINE

Therapeutic targeting of EPH receptors and their ligands

(2013) Andrew W. Boyd et al.   NATURE REVIEWS DRUG DISCOVERY

Phase II randomized, double-blind, placebo-controlled study of whole-brain irradiation with concomitant chloroquine for brain metastases

(2013) Luis L Rojas-Puentes et al.   Radiation Oncology

Autophagy: shaping the tumor microenvironment and therapeutic response

(2013) Hannelore Maes et al.   TRENDS IN MOLECULAR MEDICINE

Recycling endosomes contribute to autophagosome formation

(2012) Andrea Longatti et al.   Autophagy

Blocking ephrinB2 with highly specific antibodies inhibits angiogenesis, lymphangiogenesis, and tumor growth

(2012) M. A. Abengozar et al.   BLOOD

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy

(2012) M. A. Swartz et al.   CANCER RESEARCH

Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling

(2012) Satish Pasula et al.   JOURNAL OF CLINICAL INVESTIGATION

Rapamycin-induced tumor vasculature remodeling in rhabdomyosarcoma xenografts increases the effectiveness of adjuvant ionizing radiation

(2012) Adrianne L. Myers et al.   JOURNAL OF PEDIATRIC SURGERY

Notch signaling from the endosome requires a conserved dileucine motif

(2012) Li Zheng et al.   MOLECULAR BIOLOGY OF THE CELL

Tumor angiogenesis is enforced by autocrine regulation of high-mobility group box 1

(2012) J R van Beijnum et al.   ONCOGENE

Secreted microRNAs: a new form of intercellular communication

(2012) Xi Chen et al.   TRENDS IN CELL BIOLOGY

Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis

(2011) Seon-Jin Lee et al.   Autophagy

Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor

(2011) W. Zheng et al.   BLOOD

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

High mobility group box 1 promotes endothelial cell angiogenic behavior in vitro and improves muscle perfusion in vivo in response to ischemic injury

(2011) Ulka Sachdev et al.   JOURNAL OF VASCULAR SURGERY

VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation

(2011) Birger Herzog et al.   MOLECULAR BIOLOGY OF THE CELL

Antiangiogenic therapy: impact on invasion, disease progression and metastasis

(2011) John M. L. Ebos et al.   Nature Reviews Clinical Oncology

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

(2011) Peter Carmeliet et al.   NATURE REVIEWS DRUG DISCOVERY

Novel Research Horizons for Presenilins and γ-Secretases in Cell Biology and Disease

(2010) Bart De Strooper et al.   Annual Review of Cell and Developmental Biology

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes

(2010) H. Sheldon et al.   BLOOD

Vessel abnormalization: another hallmark of cancer?Molecular mechanisms and therapeutic implications

(2010) Katrien De Bock et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts

(2010) Ingrid Nilsson et al.   EMBO JOURNAL

Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis

(2010) Suphansa Sawamiphak et al.   NATURE

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

The Multiple Facets of Ubiquitination in the Regulation of Notch Signaling Pathway

(2010) Stéphanie Le Bras et al.   TRAFFIC

DLL4 Blockade Inhibits Tumor Growth and Reduces Tumor-Initiating Cell Frequency

(2009) Timothy Hoey et al.   Cell Stem Cell

Endocytic regulation of Notch signaling

(2009) Mark E Fortini et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Endostatin induces autophagy in endothelial cells by modulating Beclin 1 and β-catenin levels

(2009) Tri Minh Bui Nguyen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Endocytosis and signalling: intertwining molecular networks

(2009) Alexander Sorkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lymphatic Vessel Activation in Cancer

(2008) Suvendu Das et al.   Annals of the New York Academy of Sciences

AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice

(2008) Haifeng Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

(2008) Tuomas Tammela et al.   NATURE

Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis

(2008) Y. Suarez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trafficking, a key player in regulated intramembrane proteolysis

(2008) Ragna Sannerud et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY