Cationic PTD/CPP-mediated macromolecular delivery: charging into the cell

The Effect of a Connexin43-Based Peptide on the Healing of Chronic Venous Leg Ulcers: A Multicenter, Randomized Trial

(2015) Gautam S. Ghatnekar et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Molecular interplays involved in the cellular uptake of octaarginine on cell surfaces and the importance of syndecan-4 cytoplasmic V domain for the activation of protein kinase Cα

(2014) Ikuhiko Nakase et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Efficient delivery of RNAi prodrugs containing reversible charge-neutralizing phosphotriester backbone modifications

(2014) Bryan R Meade et al.   NATURE BIOTECHNOLOGY

Cell-permeant recombinant Nanog protein promotes pluripotency by inhibiting endodermal specification

(2014) Michael Peitz et al.   Stem Cell Research

Future directions for peptide therapeutics development

(2013) Allan A. Kaspar et al.   DRUG DISCOVERY TODAY

Tumor-Penetrating Peptides

(2013) Tambet Teesalu et al.   Frontiers in Oncology

Effects of Tryptophan Content and Backbone Spacing on the Uptake Efficiency of Cell-Penetrating Peptides

(2012) Hanna A. Rydberg et al.   BIOCHEMISTRY

Cell surface binding and uptake of arginine- and lysine-rich penetratin peptides in absence and presence of proteoglycans

(2012) Helene L. Åmand et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cell-penetrating peptides (CPPs) as a vector for the delivery of siRNAs into cells

(2012) Ikuhiko Nakase et al.   Molecular BioSystems

Do Cell-Penetrating Peptides Actually “Penetrate” Cellular Membranes?

(2012) Caroline Palm-Apergi et al.   MOLECULAR THERAPY

Cell-penetrating peptides: breaking through to the other side

(2012) Erez Koren et al.   TRENDS IN MOLECULAR MEDICINE

Harnessing the power of cell-penetrating peptides: activatable carriers for targeting systemic delivery of cancer therapeutics and imaging agents

(2012) Sarah R. MacEwan et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Cell-Penetrating Peptides, PepFects, Show No Evidence of Toxicity and ImmunogenicityIn VitroandIn Vivo

(2011) Julia Suhorutsenko et al.   BIOCONJUGATE CHEMISTRY

Protein transduction domain delivery of therapeutic macromolecules

(2011) Arjen van den Berg et al.   CURRENT OPINION IN BIOTECHNOLOGY

Single Particle Tracking Confirms That Multivalent Tat Protein Transduction Domain-induced Heparan Sulfate Proteoglycan Cross-linkage Activates Rac1 for Internalization

(2011) Junji Imamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systemic delivery of BH4 anti-apoptotic peptide using CPPs prevents cardiac ischemia–reperfusion injuries in vivo

(2011) Prisca Boisguerin et al.   JOURNAL OF CONTROLLED RELEASE

Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo

(2011) Samir EL Andaloussi et al.   NUCLEIC ACIDS RESEARCH

Cell-penetrating peptide exploited syndecans

(2010) Tamás Letoha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Transduction of Cell-Penetrating Peptides into Induced Pluripotent Stem Cells

(2010) Hiroshi Yukawa et al.   CELL TRANSPLANTATION

Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival

(2010) Q. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biological responses towards cationic peptides and drug carriers

(2010) Wouter P.R. Verdurmen et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mechanisms of Endocytosis

(2009) Gary J. Doherty et al.   Annual Review of Biochemistry

Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics

(2009) Frederic Heitz et al.   BRITISH JOURNAL OF PHARMACOLOGY

Systemic in vivo distribution of activatable cell penetrating peptides is superior to that of cell penetrating peptides

(2009) Todd A. Aguilera et al.   Integrative Biology

Revised Role of Glycosaminoglycans in TAT Protein Transduction Domain-mediated Cellular Transduction

(2009) Jacob M. Gump et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhanced intracellular delivery using arginine-rich peptides by the addition of penetration accelerating sequences (Pas)

(2009) Kentaro Takayama et al.   JOURNAL OF CONTROLLED RELEASE

Efficient siRNA delivery into primary cells by a peptide transduction domain–dsRNA binding domain fusion protein

(2009) Akiko Eguchi et al.   NATURE BIOTECHNOLOGY

Connexin43 carboxyl-terminal peptides reduce scar progenitor and promote regenerative healing following skin wounding

(2009) Gautam S Ghatnekar et al.   Regenerative Medicine

Stimulated endocytosis in penetratin uptake: Effect of arginine and lysine

(2008) Helene L. Åmand et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Generation of transducible versions of transcription factors Oct4 and Sox2

(2008) Manal Bosnali et al.   BIOLOGICAL CHEMISTRY

An endosomolytic Tat peptide produced by incorporation of histidine and cysteine residues as a nonviral vector for DNA transfection

(2008) Seong Loong Lo et al.   BIOMATERIALS