One-week glucose control via zero-order release kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer

Injectable and Thermosensitive Hydrogel Containing Liraglutide as a Long-Acting Antidiabetic System

(2016) Yipei Chen et al.   ACS Applied Materials & Interfaces

Controlled release of biologics for the treatment of type 2 diabetes

(2016) Caslin A. Gilroy et al.   JOURNAL OF CONTROLLED RELEASE

The Current Drug Treatment Landscape for Diabetes and Perspectives for the Future

(2015) CJ Bailey   CLINICAL PHARMACOLOGY & THERAPEUTICS

Management of hyperglycaemia in type 2 diabetes, 2015: a patient-centred approach. Update to a Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes

(2015) Silvio E. Inzucchi et al.   DIABETOLOGIA

Injectable controlled release depots for large molecules

(2014) Steven P. Schwendeman et al.   JOURNAL OF CONTROLLED RELEASE

Clinical Pharmacology of Albiglutide, a GLP-1 Receptor Agonist

(2014) Malcolm A. Young et al.   POSTGRADUATE MEDICINE

A Unified Model for De Novo Design of Elastin-like Polypeptides with Tunable Inverse Transition Temperatures

(2013) Jonathan R. McDaniel et al.   BIOMACROMOLECULES

Blood Glucose Levels in Rhesus Monkeys (Macaca mulatta) and Cynomolgus Macaques (Macaca fascicularis) under Moderate Stress and after Recovery

(2013) B. A. Lapin et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

A depot-forming glucagon-like peptide-1 fusion protein reduces blood glucose for five days with a single injection

(2013) M. Amiram et al.   JOURNAL OF CONTROLLED RELEASE

In Vitro and In Vivo Evaluation of a Once-weekly Formulation of an Antidiabetic Peptide Drug Exenatide in an Injectable Thermogel

(2013) Lin Yu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

An Evidence-Based and Practical Approach to Using Bydureon  in Patients With Type 2 Diabetes

(2013) N. A. Painter et al.   Journal of the American Board of Family Medicine

Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control

(2013) M. Amiram et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Applications of Human Pharmacokinetic Prediction in First-in-Human Dose Estimation

(2012) Peng Zou et al.   AAPS Journal

GLP-1 receptor activated insulin secretion from pancreatic β-cells: mechanism and glucose dependence

(2012) A. R. Meloni et al.   DIABETES OBESITY & METABOLISM

Effects of increasing doses of glucagon-like peptide-1 on insulin-releasing phases during intravenous glucose administration in mice

(2011) Hui Min Chan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

An overview of once-weekly glucagon-like peptide-1 receptor agonists-available efficacy and safety data and perspectives for the future

(2011) S. Madsbad et al.   DIABETES OBESITY & METABOLISM

Encapsulation of Exenatide in Poly-(d,l-Lactide-Co-Glycolide) Microspheres Produced an Investigational Long-Acting Once-Weekly Formulation for Type 2 Diabetes

(2011) Mary Beth DeYoung et al.   Diabetes Technology & Therapeutics

Recursive Directional Ligation by Plasmid Reconstruction Allows Rapid and Seamless Cloning of Oligomeric Genes

(2010) Jonathan R. McDaniel et al.   BIOMACROMOLECULES

Elastin-like polypeptides: Biomedical applications of tunable biopolymers

(2010) Sarah R. MacEwan et al.   BIOPOLYMERS

Engineering and characterization of the long-acting glucagon-like peptide-1 analogue LY2189265, an Fc fusion protein

(2010) Wolfgang Glaesner et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Delivery of Therapeutic Proteins

(2010) Dipak S. Pisal et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Immunogenicity of biologically-derived therapeutics: Assessment and interpretation of nonclinical safety studies

(2009) Rafael Ponce et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Pharmacodynamics, Pharmacokinetics, Safety, and Tolerability of Albiglutide, a Long-Acting Glucagon-Like Peptide-1 Mimetic, in Patients with Type 2 Diabetes

(2008) Jessica E. Matthews et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Design and Synthesis of Conformationally Constrained Glucagon-Like Peptide-1 Derivatives with Increased Plasma Stability and Prolonged in Vivo Activity

(2008) Les P. Miranda et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pharmacokinetic and pharmacodynamic evaluation of site-specific PEGylated glucagon-like peptide-1 analogs as flexible postprandial-glucose controllers

(2008) Su Young Chae et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Effects of Hofmeister Anions on the Phase Transition Temperature of Elastin-like Polypeptides

(2008) Younhee Cho et al.   JOURNAL OF PHYSICAL CHEMISTRY B