标题
Dysbiosis of gut microbiota in promoting the development of colorectal cancer
作者
关键词
-
出版物
Gastroenterology Report
Volume 6, Issue 1, Pages 1-12
出版商
Oxford University Press (OUP)
发表日期
2017-08-02
DOI
10.1093/gastro/gox031
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE 2 -Mediated Suppression of Antitumor Immunity
- (2017) Tze Mun Loo et al. Cancer Discovery
- Carcinogenesis and therapeutics: the microbiota perspective
- (2017) Matthew C. B. Tsilimigras et al. Nature Microbiology
- Dysbiosis of the fecal microbiota in the TNBS-induced Crohn’s disease mouse model
- (2016) Qing He et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Probiotics, prebiotics and colorectal cancer prevention
- (2016) Padma Ambalam et al. BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
- Deoxycholic acid mediates non-canonical EGFR-MAPK activation through the induction of calcium signaling in colon cancer cells
- (2016) Sara M. Centuori et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Lactobacillus rhamnosus induced epithelial cell apoptosis, ameliorates inflammation and prevents colon cancer development in an animal model
- (2016) Yaser Gamallat et al. BIOMEDICINE & PHARMACOTHERAPY
- Targeting Inflammation in Cancer Prevention and Therapy
- (2016) J. Todoric et al. Cancer Prevention Research
- Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations
- (2016) Christoph A. Thaiss et al. CELL
- Structural Change in Microbiota by a Probiotic Cocktail Enhances the Gut Barrier and Reduces Cancer via TLR2 Signaling in a Rat Model of Colon Cancer
- (2016) Eugene Dogkotenge Kuugbee et al. DIGESTIVE DISEASES AND SCIENCES
- Opposing effects of bile acids deoxycholic acid and ursodeoxycholic acid on signal transduction pathways in oesophageal cancer cells
- (2016) Mohamed M. Abdel-Latif et al. EUROPEAN JOURNAL OF CANCER PREVENTION
- Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism
- (2016) Thibaut Duparc et al. GUT
- The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls
- (2016) Martin Kummen et al. GUT
- Effects of Probiotics on Intestinal Mucosa Barrier in Patients With Colorectal Cancer after Operation
- (2016) Dun Liu et al. MEDICINE
- Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tissues
- (2016) Kimberly A. Krautkramer et al. MOLECULAR CELL
- The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis
- (2016) E Thiele Orberg et al. Mucosal Immunology
- Epithelial calcineurin controls microbiota-dependent intestinal tumor development
- (2016) Kenneth Peuker et al. NATURE MEDICINE
- High-fat Western diet–induced obesity contributes to increased tumor growth in mouse models of human colon cancer
- (2016) Ann Marie O'Neill et al. NUTRITION RESEARCH
- Gut microbiota imbalance and colorectal cancer
- (2016) Johan Gagnière WORLD JOURNAL OF GASTROENTEROLOGY
- Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis
- (2016) Krista Dubin et al. Nature Communications
- Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development
- (2016) Kazuhiko Uchiyama et al. Scientific Reports
- Bile acid: a potential inducer of colon cancer stem cells
- (2016) Lulu Farhana et al. Stem Cell Research & Therapy
- Propionate Ameliorates Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal Barrier Function and Reducing Inflammation and Oxidative Stress
- (2016) Ling-chang Tong et al. Frontiers in Pharmacology
- Gut microbial metabolism and colon cancer: Can manipulations of the microbiota be useful in the management of gastrointestinal health?
- (2015) Antoaneta Belcheva et al. BIOESSAYS
- A genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine N-oxide (TMAO), a gut microbial metabolite of dietary meat and fat
- (2015) Rong Xu et al. BMC GENOMICS
- Global cancer statistics, 2012
- (2015) Lindsey A. Torre et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Bacteria Moving into Focus of Human Cancer
- (2015) Francesco Boccellato et al. Cell Host & Microbe
- Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella
- (2015) Petia Kovatcheva-Datchary et al. Cell Metabolism
- Bile acids as metabolic regulators
- (2015) Tiangang Li et al. CURRENT OPINION IN GASTROENTEROLOGY
- Prevention of colorectal cancer: How many tools do we have in our basket?
- (2015) Luca Roncucci et al. European Journal of Internal Medicine
- Fusobacterium nucleatumin colorectal carcinoma tissue and patient prognosis
- (2015) Kosuke Mima et al. GUT
- Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer
- (2015) Jun Yu et al. GUT
- The gut microbiota and host health: a new clinical frontier
- (2015) Julian R Marchesi et al. GUT
- Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack
- (2015) Chamutal Gur et al. IMMUNITY
- Inactivation of Adenomatous Polyposis Coli Reduces Bile Acid/Farnesoid X Receptor Expression through Fxr gene CpG Methylation in Mouse Colon Tumors and Human Colon Cancer Cells
- (2015) Ornella I Selmin et al. JOURNAL OF NUTRITION
- Prevalence of Mycobacterium avium subsp. paratuberculosis and Escherichia coli in blood samples from patients with inflammatory bowel disease
- (2015) Nair Nazareth et al. MEDICAL MICROBIOLOGY AND IMMUNOLOGY
- A catalog of the mouse gut metagenome
- (2015) Liang Xiao et al. NATURE BIOTECHNOLOGY
- Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance
- (2015) Sungsoon Fang et al. NATURE MEDICINE
- Endocannabinoids — at the crossroads between the gut microbiota and host metabolism
- (2015) Patrice D. Cani et al. Nature Reviews Endocrinology
- Processed and Unprocessed Red Meat and Risk of Colorectal Cancer: Analysis by Tumor Location and Modification by Time
- (2015) Adam M. Bernstein et al. PLoS One
- Could microbial therapy boost cancer immunotherapy?
- (2015) A. Snyder et al. SCIENCE
- Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy
- (2015) A. Sivan et al. SCIENCE
- Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
- (2015) M. Vetizou et al. SCIENCE
- Fecal microbes, short chain fatty acids, and colorectal cancer across racial/ethnic groups
- (2015) Christina M Hester WORLD JOURNAL OF GASTROENTEROLOGY
- Gut microbiome development along the colorectal adenoma–carcinoma sequence
- (2015) Qiang Feng et al. Nature Communications
- Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis
- (2015) A. L. Geis et al. Cancer Discovery
- FusobacteriumandEscherichia: models of colorectal cancer driven by microbiota and the utility of microbiota in colorectal cancer screening
- (2015) Andrea Leung et al. Expert Review of Gastroenterology & Hepatology
- Vegetarian Dietary Patterns and the Risk of Colorectal Cancers
- (2015) Michael J. Orlich et al. JAMA Internal Medicine
- Inflammatory Bowel Disease: Genetics, Epigenetics, and Pathogenesis
- (2015) Italia Loddo et al. Frontiers in Immunology
- Fusobacterium nucleatumand T Cells in Colorectal Carcinoma
- (2015) Kosuke Mima et al. JAMA Oncology
- Bile acid nuclear receptor FXR and digestive system diseases
- (2015) Lili Ding et al. Acta Pharmaceutica Sinica B
- Gut Microbiome and Colorectal Adenomas
- (2014) Santosh Dulal et al. CANCER JOURNAL
- Plasma Choline Metabolites and Colorectal Cancer Risk in the Women's Health Initiative Observational Study
- (2014) S. Bae et al. CANCER RESEARCH
- Role of the Microbiota in Immunity and Inflammation
- (2014) Yasmine Belkaid et al. CELL
- Microbial-Derived Butyrate: An Oncometabolite or Tumor-Suppressive Metabolite?
- (2014) Scott J. Bultman et al. Cell Host & Microbe
- Microbes, Microbiota, and Colon Cancer
- (2014) Cynthia L. Sears et al. Cell Host & Microbe
- The Bacteroides fragilis Toxin Gene Is Prevalent in the Colon Mucosa of Colorectal Cancer Patients
- (2014) Annemarie Boleij et al. CLINICAL INFECTIOUS DISEASES
- Bile acids and the gut microbiome
- (2014) Jason M. Ridlon et al. CURRENT OPINION IN GASTROENTEROLOGY
- Differential Regulation of EGFR–MAPK Signaling by Deoxycholic Acid (DCA) and Ursodeoxycholic Acid (UDCA) in Colon Cancer
- (2014) Sara M. Centuori et al. DIGESTIVE DISEASES AND SCIENCES
- Gastrointestinal Malignancy and the Microbiome
- (2014) Maria T. Abreu et al. GASTROENTEROLOGY
- Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
- (2014) Nagendra Singh et al. IMMUNITY
- Diet, Microbiota, and Colorectal Cancer
- (2014) Hakan Akin et al. JOURNAL OF CLINICAL GASTROENTEROLOGY
- The contributory role of gut microbiota in cardiovascular disease
- (2014) W.H. Wilson Tang et al. JOURNAL OF CLINICAL INVESTIGATION
- Bacteroides fragilis subverts mucosal biology: from symbiont to colon carcinogenesis
- (2014) Cynthia L. Sears et al. JOURNAL OF CLINICAL INVESTIGATION
- Beyond intestinal soap—bile acids in metabolic control
- (2014) Folkert Kuipers et al. Nature Reviews Endocrinology
- Microbiota organization is a distinct feature of proximal colorectal cancers
- (2014) Christine M. Dejea et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cysteinyl leukotrienes and their receptors: Bridging inflammation and colorectal cancer
- (2014) Sayeh Savari WORLD JOURNAL OF GASTROENTEROLOGY
- Secondary bile acids: an underrecognized cause of colon cancer
- (2014) Hana Ajouz et al. World Journal of Surgical Oncology
- Microbial genomic analysis reveals the essential role of inflammation in bacteria-induced colorectal cancer
- (2014) Janelle C. Arthur et al. Nature Communications
- Multiple Roles of Toll-Like Receptor 4 in Colorectal Cancer
- (2014) Dhanusha Yesudhas et al. Frontiers in Immunology
- Structure of the gut microbiome following colonization with human feces determines colonic tumor burden
- (2014) Nielson T Baxter et al. Microbiome
- Helicobacter pylori Protein-Specific Antibodies and Risk of Colorectal Cancer
- (2013) M. Epplein et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment
- (2013) Aleksandar D. Kostic et al. Cell Host & Microbe
- Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin
- (2013) Mara Roxana Rubinstein et al. Cell Host & Microbe
- Colonization of the Human Gut by E. coli and Colorectal Cancer Risk
- (2013) M. Bonnet et al. CLINICAL CANCER RESEARCH
- Colonic bacterial metabolites and human health
- (2013) Wendy R Russell et al. CURRENT OPINION IN MICROBIOLOGY
- Human Insulin Resistance Is Associated With Increased Plasma Levels of 12 -Hydroxylated Bile Acids
- (2013) R. A. Haeusler et al. DIABETES
- Human Gut Microbiome and Risk for Colorectal Cancer
- (2013) Jiyoung Ahn et al. JNCI-Journal of the National Cancer Institute
- Probiotics, gut microbiota and health
- (2013) M.-J. Butel MEDECINE ET MALADIES INFECTIEUSES
- Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis
- (2013) Robert A Koeth et al. NATURE MEDICINE
- Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk
- (2013) W.H. Wilson Tang et al. NEW ENGLAND JOURNAL OF MEDICINE
- High Prevalence of Mucosa-Associated E. coli Producing Cyclomodulin and Genotoxin in Colon Cancer
- (2013) Emmanuel Buc et al. PLoS One
- Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment
- (2013) N. Iida et al. SCIENCE
- The Long-Term Stability of the Human Gut Microbiota
- (2013) J. J. Faith et al. SCIENCE
- Fusobacterium spp. and colorectal cancer: cause or consequence?
- (2013) Temitope O. Keku et al. TRENDS IN MICROBIOLOGY
- Biomarkers in precision therapy in colorectal cancer
- (2013) M. S. Reimers et al. Gastroenterology Report
- Active vitamin D (1,25-dihydroxyvitamin D3) increases host susceptibility to Citrobacter rodentium by suppressing mucosal Th17 responses
- (2012) Natasha R. Ryz et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Enterococcus faecalis Enhances Cell Proliferation through Hydrogen Peroxide-Mediated Epidermal Growth Factor Receptor Activation
- (2012) Kanitsak Boonanantanasarn et al. INFECTION AND IMMUNITY
- The deoxycholic acid targets miRNA-dependent CAC1 gene expression in multidrug resistance of human colorectal cancer
- (2012) Ying Kong et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- A metagenome-wide association study of gut microbiota in type 2 diabetes
- (2012) Junjie Qin et al. NATURE
- Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota
- (2012) J. C. Arthur et al. SCIENCE
- The human commensal Bacteroides fragilis binds intestinal mucin
- (2011) Julie Y. Huang et al. ANAEROBE
- Metformin and thiazolidinediones are associated with improved breast cancer-specific survival of diabetic women with HER2+ breast cancer
- (2011) X. He et al. ANNALS OF ONCOLOGY
- Thiazolidinediones and metformin associated with improved survival of diabetic prostate cancer patients
- (2011) X.- X. He et al. ANNALS OF ONCOLOGY
- Deoxycholic and chenodeoxycholic bile acids induce apoptosis via oxidative stress in human colon adenocarcinoma cells
- (2011) Juan Ignacio Barrasa et al. APOPTOSIS
- Cultured Representatives of Two Major Phylogroups of Human Colonic Faecalibacterium prausnitzii Can Utilize Pectin, Uronic Acids, and Host-Derived Substrates for Growth
- (2011) Mireia Lopez-Siles et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Oral inoculation of probiotics Lactobacillus acidophilus NCFM suppresses tumour growth both in segmental orthotopic colon cancer and extra-intestinal tissue
- (2011) Chien-Chang Chen et al. BRITISH JOURNAL OF NUTRITION
- Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma
- (2011) M. Castellarin et al. GENOME RESEARCH
- Genomic analysis identifies association of Fusobacterium with colorectal carcinoma
- (2011) A. D. Kostic et al. GENOME RESEARCH
- Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner
- (2011) Matthew A Ciorba et al. GUT
- Invasive potential of gut mucosa-derived fusobacterium nucleatum positively correlates with IBD status of the host
- (2011) Jaclyn Strauss et al. INFLAMMATORY BOWEL DISEASES
- Toll-like receptor 2 monoclonal antibody or/and Toll-like receptor 4 monoclonal antibody increase counts of Lactobacilli and Bifidobacteria in dextran sulfate sodium-induced colitis in mice
- (2011) Le Dong et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- A Functional Role for Nlrp6 in Intestinal Inflammation and Tumorigenesis
- (2011) G. Y. Chen et al. JOURNAL OF IMMUNOLOGY
- Butyrate-Induced Apoptosis in HCT116 Colorectal Cancer Cells Includes Induction of a Cell Stress Response
- (2011) Kim Y. C. Fung et al. JOURNAL OF PROTEOME RESEARCH
- Fusobacterium nucleatum adhesin FadA binds vascular endothelial cadherin and alters endothelial integrity
- (2011) Yann Fardini et al. MOLECULAR MICROBIOLOGY
- Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
- (2011) Zeneng Wang et al. NATURE
- Dose-Dependent Immunomodulation of Human Dendritic Cells by the Probiotic Lactobacillus rhamnosus Lcr35
- (2011) Bertrand Evrard et al. PLoS One
- The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota
- (2011) J. L. Round et al. SCIENCE
- Understanding the role of gut microbiome–host metabolic signal disruption in health and disease
- (2011) Elaine Holmes et al. TRENDS IN MICROBIOLOGY
- High expression of Toll-like receptor 4/myeloid differentiation factor 88 signals correlates with poor prognosis in colorectal cancer
- (2010) E L Wang et al. BRITISH JOURNAL OF CANCER
- Bile acids modulate the Golgi membrane fission process via a protein kinase Cη and protein kinase D-dependent pathway in colonic epithelial cells
- (2010) Anne-Marie Byrne et al. CARCINOGENESIS
- Regulation of Nur77 expression by β-catenin and its mitogenic effect in colon cancer cells
- (2010) Hua Wu et al. FASEB JOURNAL
- ERK activation drives intestinal tumorigenesis in Apcmin/+ mice
- (2010) Sung Hee Lee et al. NATURE MEDICINE
- Toll-Like Receptor 2 Signaling Protects Mice from Tumor Development in a Mouse Model of Colitis-Induced Cancer
- (2010) Emily L. Lowe et al. PLoS One
- Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme
- (2010) B. D. Wallace et al. SCIENCE
- Targeting Cell Metabolism in Cancer Patients
- (2010) M. G. Vander Heiden Science Translational Medicine
- IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
- (2009) Sergei Grivennikov et al. CANCER CELL
- Lithocholic acid upregulates uPAR and cell invasiveness via MAPK and AP-1 signaling in colon cancer cells
- (2009) Min Kyung Baek et al. CANCER LETTERS
- Role of TLR4 for paclitaxel chemotherapy in human epithelial ovarian cancer cells
- (2009) A. C. Wang et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Low counts of Faecalibacterium prausnitzii in colitis microbiota
- (2009) H. Sokol et al. INFLAMMATORY BOWEL DISEASES
- TLR4-Mediated Podosome Loss Discriminates Gram-Negative from Gram-Positive Bacteria in Their Capacity to Induce Dendritic Cell Migration and Maturation
- (2009) S. F. G. van Helden et al. JOURNAL OF IMMUNOLOGY
- A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
- (2009) Shaoguang Wu et al. NATURE MEDICINE
- Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells
- (2009) J. Yun et al. SCIENCE
- Inhibition of proliferation in colon cancer cell lines and harmful enzyme activity of colon bacteria by Bifidobacterium adolescentis SPM0212
- (2008) Yuna Kim et al. ARCHIVES OF PHARMACAL RESEARCH
- In vivovirulence properties of bacterial cytolethal-distending toxin
- (2008) Zhongming Ge et al. CELLULAR MICROBIOLOGY
- Real-time polymerase chain reaction quantification of specific butyrate-producing bacteria,DesulfovibrioandEnterococcus faecalisin the feces of patients with colorectal cancer
- (2008) Ramadass Balamurugan et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Ursodeoxycholic Acid Suppresses Cox-2 Expression in Colon Cancer: Roles of Ras, p38, and CCAAT/Enhancer-Binding Protein
- (2008) Sharad Khare et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key?
- (2008) Roberto Scatena et al. PPAR Research
- Enterotoxigenic Bacteroides fragilis
- (2008) John Holton Current Infectious Disease Reports
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started