The skin microbiome: impact of modern environments on skin ecology, barrier integrity, and systemic immune programming

Soil microbial communities are shaped by vegetation type and park age in cities under cold climate

(2017) Nan Hui et al.   ENVIRONMENTAL MICROBIOLOGY

Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year

(2017) Elizabeth A. Kennedy et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The rarity of direct experiences of nature in an urban population

(2017) Daniel T.C. Cox et al.   LANDSCAPE AND URBAN PLANNING

Maturation of the infant microbiome community structure and function across multiple body sites and in relation to mode of delivery

(2017) Derrick M Chu et al.   NATURE MEDICINE

Weissella cibaria WIKIM28 ameliorates atopic dermatitis-like skin lesions by inducing tolerogenic dendritic cells and regulatory T cells in BALB/c mice

(2017) Seul Ki Lim et al.   Scientific Reports

Patterns in the skin microbiota differ in children and teenagers between rural and urban environments

(2017) Jenni Lehtimäki et al.   Scientific Reports

A critical assessment of the “sterile womb” and “in utero colonization” hypotheses: implications for research on the pioneer infant microbiome

(2017) Maria Elisa Perez-Muñoz et al.   Microbiome

Associations of outdoor play and screen time with nocturnal sleep duration and pattern among young children

(2016) Huilan Xu et al.   ACTA PAEDIATRICA

Domestic dog exposure at birth reduces the incidence of atopic dermatitis

(2016) S. Thorsteinsdottir et al.   ALLERGY

Contribution of Vegetation to the Microbial Composition of Nearby Outdoor Air

(2016) Despoina S. Lymperopoulou et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Microbiota induces expression of tumor necrosis factor in postnatal mouse skin

(2016) D. V. Yuzhakova et al.   BIOCHEMISTRY-MOSCOW

The mode of delivery affects the diversity and colonization pattern of the gut microbiota during the first year of infants' life: a systematic review

(2016) Erigene Rutayisire et al.   BMC GASTROENTEROLOGY

The role of skin and gut microbiota in the development of atopic eczema

(2016) T. Marrs et al.   BRITISH JOURNAL OF DERMATOLOGY

The Human Microbiome before Birth

(2016) Martin J. Blaser et al.   Cell Host & Microbe

Immune-Microbiota Interactions: Dysbiosis as a Global Health Issue

(2016) Alan C. Logan et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Bifidobacterium longumextract exerts pro-differentiating effects on human epidermal keratinocytes, in vitro

(2016) Attila Gábor Szöllősi et al.   EXPERIMENTAL DERMATOLOGY

The effect of heritability and host genetics on the gut microbiota and metabolic syndrome

(2016) Mi Young Lim et al.   GUT

Perinatal microbial exposure may influence aortic intima-media thickness in early infancy

(2016) Kate McCloskey et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The skin microbiome is different in pediatric versus adult atopic dermatitis

(2016) Baochen Shi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Topical application of probiotics in skin: adhesion, antimicrobial and antibiofilmin vitroassays

(2016) E.G. Lopes et al.   JOURNAL OF APPLIED MICROBIOLOGY

Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer

(2016) Maria G Dominguez-Bello et al.   NATURE MEDICINE

Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children

(2016) Michelle M. Stein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Probiotic supplementation can positively affect anxiety and depressive symptoms: a systematic review of randomized controlled trials

(2016) Meysam Pirbaglou et al.   NUTRITION RESEARCH

The role of barrier genes in epidermal malignancy

(2016) C Darido et al.   ONCOGENE

Is there a march from early food sensitization to later childhood allergic airway disease? Results from two prospective birth cohort studies

(2016) Shatha A. Alduraywish et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Immunization with a heat-killed preparation of the environmental bacteriumMycobacterium vaccaepromotes stress resilience in mice

(2016) Stefan O. Reber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Urban greenness influences airborne bacterial community composition

(2016) Gwynne Mhuireach et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Effect of Probiotics on Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

(2016) Ruixue Huang et al.   Nutrients

Supplementation with Lactobacillus rhamnosus SP1 normalises skin expression of genes implicated in insulin signalling and improves adult acne

(2016) G. Fabbrocini et al.   Beneficial Microbes

Both Direct and Vicarious Experiences of Nature Affect Children’s Willingness to Conserve Biodiversity

(2016) Masashi Soga et al.   International Journal of Environmental Research and Public Health

Effect of Substance P in Staphylococcus aureus and Staphylococcus epidermidis Virulence: Implication for Skin Homeostasis

(2016) Awa N'Diaye et al.   Frontiers in Microbiology

The Microbiome and Mental Health: Looking Back, Moving Forward with Lessons from Allergic Diseases

(2016) Alan C. Logan et al.   Clinical Psychopharmacology and Neuroscience

Natural environments, nature relatedness and the ecological theater: connecting satellites and sequencing to shinrin-yoku

(2016) Jeffrey M. Craig et al.   Journal of Physiological Anthropology

Toward a microbial Neolithic revolution in buildings

(2016) David S. Thaler   Microbiome

Whole metagenome profiling reveals skin microbiome-dependent susceptibility to atopic dermatitis flare

(2016) Kern Rei Chng et al.   Nature Microbiology

Particularities of allergy in the Tropics

(2016) Luis Caraballo et al.   World Allergy Organization Journal

World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Prebiotics

(2016) Carlos A. Cuello-Garcia et al.   World Allergy Organization Journal

Colonization with the enteric protozoa Blastocystis is associated with increased diversity of human gut bacterial microbiota

(2016) Christophe Audebert et al.   Scientific Reports

The balance of metagenomic elements shapes the skin microbiome in acne and health

(2016) Emma Barnard et al.   Scientific Reports

Green areas around homes reduce atopic sensitization in children

(2015) L. Ruokolainen et al.   ALLERGY

Neighborhood Blight, Stress, and Health: A Walking Trial of Urban Greening and Ambulatory Heart Rate

(2015) Eugenia C. South et al.   AMERICAN JOURNAL OF PUBLIC HEALTH

Helsinki alert of biodiversity and health

(2015) Leena von Hertzen et al.   ANNALS OF MEDICINE

Atopic Dermatitis: Global Epidemiology and Risk Factors

(2015) Sophie Nutten   ANNALS OF NUTRITION AND METABOLISM

Genetic associations and shared environmental effects on the skin microbiome of Korean twins

(2015) Jiyeon Si et al.   BMC GENOMICS

Extensive Strain-Level Copy-Number Variation across Human Gut Microbiome Species

(2015) Sharon Greenblum et al.   CELL

Gut Microbiome: Westernization and the Disappearance of Intestinal Diversity

(2015) Nicola Segata   CURRENT BIOLOGY

The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia

(2015) Tim J Schuijt et al.   GUT

A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes

(2015) Tiffany C. Scharschmidt et al.   IMMUNITY

Dysbiosis and Staphylococcus aureus Colonization Drives Inflammation in Atopic Dermatitis

(2015) Tetsuro Kobayashi et al.   IMMUNITY

Papain Degrades Tight Junction Proteins of Human Keratinocytes In Vitro and Sensitizes C57BL/6 Mice via the Skin Independent of its Enzymatic Activity or TLR4 Activation

(2015) Caroline Stremnitzer et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Probiotic administration can prevent necrotizing enterocolitis in preterm infants: A meta-analysis

(2015) Christine S.M. Lau et al.   JOURNAL OF PEDIATRIC SURGERY

Safeguarding human health in the Anthropocene epoch: report of The Rockefeller Foundation–Lancet Commission on planetary health

(2015) Sarah Whitmee et al.   LANCET

Temporal changes in the skinMalasseziamicrobiota of members of the Japanese Antarctic Research Expedition (JARE): A case study in Antarctica as a pseudo-space environment

(2015) Takashi Sugita et al.   MEDICAL MYCOLOGY

The Diverse Microbiome of the Hunter-Gatherer

(2015) Stephanie L. Schnorr   NATURE

Potential role of the intestinal microbiota in programming health and disease: Figure 1

(2015) Olivier Goulet   NUTRITION REVIEWS

Live and Heat-KilledLactobacillus rhamnosusATCC 7469 May Induce Modulatory Cytokines Profiles on Macrophages RAW 264.7

(2015) Adeline Lacerda Jorjão et al.   TheScientificWorldJOURNAL

Host Biology in Light of the Microbiome: Ten Principles of Holobionts and Hologenomes

(2015) Seth R. Bordenstein et al.   PLOS BIOLOGY

Live and Heat-KilledLactobacillus rhamnosusATCC 7469 May Induce Modulatory Cytokines Profiles on Macrophages RAW 264.7

(2015) Adeline Lacerda Jorjão et al.   Scientific World Journal

Humans differ in their personal microbial cloud

(2015) James F. Meadow et al.   PeerJ

The microbiome of the built environment and mental health

(2015) Andrew J. Hoisington et al.   Microbiome

World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Probiotics

(2015) Alessandro Fiocchi et al.   World Allergy Organization Journal

The Influence of Age and Gender on Skin-Associated Microbial Communities in Urban and Rural Human Populations

(2015) Shi Ying et al.   PLoS One

Oral administration of Bifidobacterium breve attenuates UV-induced barrier perturbation and oxidative stress in hairless mice skin

(2014) Yuki Ishii et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Altering the Intestinal Microbiota during a Critical Developmental Window Has Lasting Metabolic Consequences

(2014) Laura M. Cox et al.   CELL

The gut microbiota and its role in the development of allergic disease: a wider perspective

(2014) C. E. West et al.   CLINICAL AND EXPERIMENTAL ALLERGY

‘Ecological embeddedness’ and Its Public Health Implications: Findings From an Exploratory Study

(2014) Marina Lewis et al.   EcoHealth

Place of upbringing in early childhood as related to inflammatory bowel diseases in adulthood: a population-based cohort study in Northern Europe

(2014) Signe Timm et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Acinetobacter species in the skin microbiota protect against allergic sensitization and inflammation

(2014) Nanna Fyhrquist et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention

(2014) Eric L. Simpson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Application of moisturizer to neonates prevents development of atopic dermatitis

(2014) Kenta Horimukai et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Probiotics and prebiotics in dermatology

(2014) Katherine L. Baquerizo Nole et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Hand bacterial communities vary across two different human populations

(2014) D. Hospodsky et al.   MICROBIOLOGY-SGM

Biogeography and individuality shape function in the human skin metagenome

(2014) Julia Oh et al.   NATURE

Maternal influences on fetal microbial colonization and immune development

(2014) Joann Romano-Keeler et al.   PEDIATRIC RESEARCH

Associations of Physical Activity, Screen Time with Depression, Anxiety and Sleep Quality among Chinese College Freshmen

(2014) Qi Feng et al.   PLoS One

The Placenta Harbors a Unique Microbiome

(2014) K. Aagaard et al.   Science Translational Medicine

Age-dependent changes in stratum corneum barrier function

(2014) E. Boireau-Adamezyk et al.   SKIN RESEARCH AND TECHNOLOGY

Microbiota in Healthy Skin and in Atopic Eczema

(2014) Giuseppe Baviera et al.   Biomed Research International

Mobile phones carry the personal microbiome of their owners

(2014) James F. Meadow et al.   PeerJ

Bacterial communities on classroom surfaces vary with human contact

(2014) James F Meadow et al.   Microbiome

Ingestion of Mycobacterium vaccae decreases anxiety-related behavior and improves learning in mice

(2013) Dorothy M. Matthews et al.   BEHAVIOURAL PROCESSES

Prebiotic supplementation in preterm neonates: Updated systematic review and meta-analysis of randomised controlled trials

(2013) Ravisha Srinivasjois et al.   CLINICAL NUTRITION

The Relationship Between Advances in Understanding the Microbiome and the Maturing Hygiene Hypothesis

(2013) Meike Bendiks et al.   CURRENT ALLERGY AND ASTHMA REPORTS

The Value of Urban Vacant Land to Support Arthropod Biodiversity and Ecosystem Services

(2013) Mary M. Gardiner et al.   ENVIRONMENTAL ENTOMOLOGY

Antimicrobial peptides and pro-inflammatory cytokines are differentially regulated across epidermal layers following bacterial stimuli

(2013) Giuseppe Percoco et al.   EXPERIMENTAL DERMATOLOGY

On the role of environmental humidity on cortisol production by epidermal keratinocytes

(2013) Guo Zhu et al.   EXPERIMENTAL DERMATOLOGY

Low environmental humidity induces synthesis and release of cortisol in an epidermal organotypic culture system

(2013) Kentaro Takei et al.   EXPERIMENTAL DERMATOLOGY

Indoor airborne bacterial communities are influenced by ventilation, occupancy, and outdoor air source

(2013) J. F. Meadow et al.   INDOOR AIR

Pet exposure and risk of atopic dermatitis at the pediatric age: A meta-analysis of birth cohort studies

(2013) Claudio Pelucchi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Early regular egg exposure in infants with eczema: A randomized controlled trial

(2013) Debra J. Palmer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Effects of a Skin Neuropeptide (Substance P) on Cutaneous Microflora

(2013) Lily Mijouin et al.   PLoS One

Regulation of the immune system by biodiversity from the natural environment: An ecosystem service essential to health

(2013) G. A. Rook   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functions of the skin microbiota in health and disease

(2013) James A. Sanford et al.   SEMINARS IN IMMUNOLOGY

The microbiome extends to subepidermal compartments of normal skin

(2013) Teruaki Nakatsuji et al.   Nature Communications

Microbial Ecology of the Skin in the Era of Metagenomics and Molecular Microbiology

(2013) G. D. Hannigan et al.   Cold Spring Harbor Perspectives in Medicine

Significant changes in the skin microbiome mediated by the sport of roller derby

(2013) James F. Meadow et al.   PeerJ

The biodiversity hypothesis and allergic disease: world allergy organization position statement

(2013) Tari Haahtela et al.   World Allergy Organization Journal

Greening vacant lots to reduce violent crime: a randomised controlled trial

(2012) Eugenia C Garvin et al.   INJURY PREVENTION

Oral tetracyclines may not be effective in treating acne: dominance of the placebo effect

(2012) Win L. Chiou   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Atopic dermatitis: correlation between non-damaged skin barrier function and disease activity

(2012) Flavia A.S. Addor et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Does diversity of environmental microbial exposure matter for the occurrence of allergy and asthma?

(2012) Dick Heederik et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Topically applied semaphorin 3A ointment inhibits scratching behavior and improves skin inflammation in NC/Nga mice with atopic dermatitis

(2012) Osamu Negi et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Use of Antibiotics during Pregnancy Increases the Risk of Asthma in Early Childhood

(2012) Lone Graff Stensballe et al.   JOURNAL OF PEDIATRICS

Solar UV radiation reduces the barrier function of human skin

(2012) K. Biniek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmental biodiversity, human microbiota, and allergy are interrelated

(2012) I. Hanski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Compartmentalized Control of Skin Immunity by Resident Commensals

(2012) S. Naik et al.   SCIENCE

Epigenetic regulation in murine offspring as a novel mechanism for transmaternal asthma protection induced by microbes

(2011) Stephanie Brand et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Diversity of the Human Skin Microbiome Early in Life

(2011) Kimberly A. Capone et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The skin microbiome

(2011) Elizabeth A. Grice et al.   NATURE REVIEWS MICROBIOLOGY

Acne vulgaris, probiotics and the gut-brain-skin axis - back to the future?

(2011) Whitney P Bowe et al.   Gut Pathogens

Environmental Determinants of and Impact on Childhood Asthma by the Bacterial Community in Household Dust

(2010) R. M. Maier et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Staphylococcus epidermidis Esp inhibits Staphylococcus aureus biofilm formation and nasal colonization

(2010) Tadayuki Iwase et al.   NATURE

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

(2010) M. G. Dominguez-Bello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exposure to In Utero Lipopolysaccharide Induces Inflammation in the Fetal Ovine Skin

(2010) Matthew W. Kemp et al.   Reproductive Sciences

Environmentally-acquired bacteria influence microbial diversity and natural innate immune responses at gut surfaces

(2009) Imke E Mulder et al.   BMC BIOLOGY

Bifidobacterium longum lysate, a new ingredient for reactive skin

(2009) Audrey Guéniche et al.   EXPERIMENTAL DERMATOLOGY

Maternal TLR signaling is required for prenatal asthma protection by the nonpathogenic microbeAcinetobacter lwoffiiF78

(2009) Melanie L. Conrad et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epidermal Barrier Dysfunction in Atopic Dermatitis

(2009) Michael J. Cork et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming

(2009) Padraic G Fallon et al.   NATURE GENETICS

Topographical and Temporal Diversity of the Human Skin Microbiome

(2009) E. A. Grice et al.   SCIENCE

Bacterial Community Variation in Human Body Habitats Across Space and Time

(2009) E. K. Costello et al.   SCIENCE

Effect of konjac glucomannan hydrolysates and probiotics on the growth of the skin bacteriumPropionibacterium acnes in vitro

(2009) F. H. Al-Ghazzewi et al.   INTERNATIONAL JOURNAL OF COSMETIC SCIENCE

Influence of substance-P on cultured sebocytes

(2008) Weon Ju Lee et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Skin microbiota: a source of disease or defence?

(2008) A.L. Cogen et al.   BRITISH JOURNAL OF DERMATOLOGY

Contrasting Immunological Effects of Two Disparate Dusts – Preliminary Observations

(2008) Harri Alenius et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Prenatal exposure to a farm environment modifies atopic sensitization at birth

(2008) Markus Johannes Ege et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Further Exploring the Brain–Skin Connection: Stress Worsens Dermatitis via Substance P-dependent Neurogenic Inflammation in Mice

(2007) Sanja Pavlovic et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY