Analysis of Purified Pancreatic Islet Beta and Alpha Cell Transcriptomes Reveals 11β-Hydroxysteroid Dehydrogenase (Hsd11b1) as a Novel Disallowed Gene

Disallowed and Allowed Gene Expression: Two Faces of Mature Islet Beta Cells

(2016) Katleen Lemaire et al.   Annual Review of Nutrition

Disallowance ofAcot7in β-Cells Is Required for Normal Glucose Tolerance and Insulin Secretion

(2016) Aida Martinez-Sanchez et al.   DIABETES

A beta cell ATGL-lipolysis/adipose tissue axis controls energy homeostasis and body weight via insulin secretion in mice

(2016) Camille Attané et al.   DIABETOLOGIA

Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

(2016) Alice E. Adriaenssens et al.   DIABETOLOGIA

PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements

(2016) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

Use of the Fluidigm C1 platform for RNA sequencing of single mouse pancreatic islet cells

(2016) Yurong Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets

(2016) Michael R. DiGruccio et al.   Molecular Metabolism

Pancreatic β-cell identity, glucose sensing and the control of insulin secretion

(2015) Guy A. Rutter et al.   BIOCHEMICAL JOURNAL

Human β-Cell Proliferation and Intracellular Signaling: Part 3

(2015) Andrew F. Stewart et al.   DIABETES

Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets

(2015) David M. Blodgett et al.   DIABETES

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Decreased 11β-Hydroxysteroid Dehydrogenase 1 Level and Activity in Murine Pancreatic Islets Caused by Insulin-Like Growth Factor I Overexpression

(2015) Subrata Chowdhury et al.   PLoS One

YAP and TAZ: a nexus for Hippo signaling and beyond

(2015) Carsten Gram Hansen et al.   TRENDS IN CELL BIOLOGY

Association of HSD11B1 polymorphic variants and adipose tissue gene expression with metabolic syndrome, obesity and type 2 diabetes mellitus: a systematic review

(2015) Filipe Valvassori do Nascimento et al.   Diabetology & Metabolic Syndrome

The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression

(2014) Christopher Benner et al.   BMC GENOMICS

LKB1 and AMPK differentially regulate pancreatic β-cell identity

(2014) Marina Kone et al.   FASEB JOURNAL

Comparison of RNA-Seq and Microarray in Transcriptome Profiling of Activated T Cells

(2014) Shanrong Zhao et al.   PLoS One

Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism

(2014) J. Fadista et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

11 -HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess

(2014) S. A. Morgan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Steroid-induced diabetes: a clinical and molecular approach to understanding and treatment

(2013) Jessica L. Hwang et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Glucocorticoid-Induced Suppression of β-Cell Proliferation Is Mediated by Mig6

(2013) E. Scott Colvin et al.   ENDOCRINOLOGY

A novel significance score for gene selection and ranking

(2012) Yufei Xiao et al.   BIOINFORMATICS

Overexpression of Monocarboxylate Transporter-1 (Slc16a1) in Mouse Pancreatic  -Cells Leads to Relative Hyperinsulinism During Exercise

(2012) T. J. Pullen et al.   DIABETES

When less is more: the forbidden fruits of gene repression in the adult β-cell

(2012) T. J. Pullen et al.   DIABETES OBESITY & METABOLISM

Dynamic Regulation of PDX-1 and FoxO1 Expression by FoxA2 in Dexamethasone-Induced Pancreatic β-cells Dysfunction

(2011) Fang Chen et al.   ENDOCRINOLOGY

IGFBP-4 activates the Wnt/beta-catenin signaling pathway and induces M-CAM expression in human renal cell carcinoma

(2011) Koji Ueno et al.   INTERNATIONAL JOURNAL OF CANCER

PDGF signalling controls age-dependent proliferation in pancreatic β-cells

(2011) Hainan Chen et al.   NATURE

Modulation of pancreatic islets-stress axis by hypothalamic releasing hormones and 11 -hydroxysteroid dehydrogenase

(2011) J. Schmid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Is 11 -HSD1 expressed in islet  -cells and regulated by corticotropin-releasing hormone?

(2011) J.-L. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocorticoids Differentially Regulate the Expression of CRFR1 and CRFR2α in MIN6 Insulinoma Cells and Rodent Islets

(2010) M. O. Huising et al.   ENDOCRINOLOGY

Tissue-specific disallowance of housekeeping genes: The other face of cell differentiation

(2010) L. Thorrez et al.   GENOME RESEARCH

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

Identification of genes selectively disallowed in the pancreatic islet

(2010) Timothy J. Pullen et al.   Islets

The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells

(2009) Patrick Collombat et al.   CELL

The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation

(2009) M. Cnop et al.   DIABETOLOGIA

Glucocorticoidsin VivoInduce Both Insulin Hypersecretion and Enhanced Glucose Sensitivity of Stimulus-Secretion Coupling in Isolated Rat Islets

(2009) Alex Rafacho et al.   ENDOCRINOLOGY

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis

(2008) M. Fex et al.   DIABETOLOGIA

Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion

(2008) C. Ling et al.   DIABETOLOGIA

Short-term glucocorticoid treatment increases insulin secretion in islets derived from lean mice through multiple pathways and mechanisms

(2008) Malin Hult et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Glucocorticoids reduce pro-inflammatory cytokines and tissue factorin vitroand improve function of transplanted human isletsin vivo

(2008) Tormod Lund et al.   TRANSPLANT INTERNATIONAL