Decreased 11β-Hydroxysteroid Dehydrogenase 1 Level and Activity in Murine Pancreatic Islets Caused by Insulin-Like Growth Factor I Overexpression

IGF-I Stimulates CCN5/WISP2 Gene Expression in Pancreatic β-Cells, Which Promotes Cell Proliferation and Survival Against Streptozotocin

(2014) Subrata Chowdhury et al.   ENDOCRINOLOGY

11β-Hydroxysteroid Dehydrogenases: Intracellular Gate-Keepers of Tissue Glucocorticoid Action

(2013) Karen Chapman et al.   PHYSIOLOGICAL REVIEWS

Optimal Elevation of  -Cell 11 -Hydroxysteroid Dehydrogenase Type 1 Is a Compensatory Mechanism That Prevents High-Fat Diet-Induced  -Cell Failure

(2012) S. Turban et al.   DIABETES

Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover

(2012) Roger H. Unger et al.   JOURNAL OF CLINICAL INVESTIGATION

Research Resource: RNA-Seq Reveals Unique Features of the Pancreatic β-Cell Transcriptome

(2012) Gregory M. Ku et al.   MOLECULAR ENDOCRINOLOGY

Pancreatic islet-specific overexpression of Reg3β protein induced the expression of pro-islet genes and protected the mice against streptozotocin-induced diabetes mellitus

(2011) Xiaoquan Xiong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Dietary manipulation reveals an unexpected inverse relationship between fat mass and adipose 11β-hydroxysteroid dehydrogenase type 1

(2011) Tak Yung Man et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Management of type 2 diabetes: new and future developments in treatment

(2011) Abd A Tahrani et al.   LANCET

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Modulation of pancreatic islets-stress axis by hypothalamic releasing hormones and 11 -hydroxysteroid dehydrogenase

(2011) J. Schmid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Is 11 -HSD1 expressed in islet  -cells and regulated by corticotropin-releasing hormone?

(2011) J.-L. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of insulin-like growth factor-I and its binding proteins in glucose homeostasis and type 2 diabetes

(2009) Swapnil N. Rajpathak et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Growth Hormone (GH) or Insulin-like Growth Factor (IGF)-I Represses 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1) mRNA Expression in 3T3-L1 Cells and Its Activity in Their Homogenates

(2009) Junko MORITA et al.   ENDOCRINE JOURNAL

Inhibition of Forkhead Box O1 Protects Pancreatic β-Cells against Dexamethasone-Induced Dysfunction

(2009) Xiongfei Zhang et al.   ENDOCRINOLOGY

The CB1 Antagonist Rimonabant Decreases Insulin Hypersecretion in Rat Pancreatic Islets

(2009) Lisa Getty-Kaushik et al.   Obesity

A general and islet cell-enriched overexpression of IGF-I results in normal islet cell growth, hypoglycemia, and significant resistance to experimental diabetes

(2008) Katie Robertson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Isosteviol increases insulin sensitivity and changes gene expression of key insulin regulatory genes and transcription factors in islets of the diabetic KKAy mouse

(2008) I. Nordentoft et al.   DIABETES OBESITY & METABOLISM

11β-Hydroxysteroid dehydrogenase type 1 regulates insulin and glucagon secretion in pancreatic islets

(2008) A. Swali et al.   DIABETOLOGIA

11-Beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors in Type 2 diabetes mellitus and obesity

(2008) Katherine A Hughes et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS