Canonical Stimulation of the NLRP3 Inflammasome by Fungal Antigens Links Innate and Adaptive B-Lymphocyte Responses by Modulating IL-1β and IgM Production

The microbiota of the respiratory tract: gatekeeper to respiratory health

(2017) Wing Ho Man et al.   NATURE REVIEWS MICROBIOLOGY

Microbial Antigens Stimulate Metalloprotease-7 Secretion in Human B-Lymphocytes Using mTOR-Dependent and Independent Pathways

(2017) Mohamed F. Ali et al.   Scientific Reports

Novel Roles for Caspase-8 in IL-1β and Inflammasome Regulation

(2015) Prajwal Gurung et al.   AMERICAN JOURNAL OF PATHOLOGY

Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling

(2015) Christina Antonopoulos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

 -Glucan-Activated Human B Lymphocytes Participate in Innate Immune Responses by Releasing Proinflammatory Cytokines and Stimulating Neutrophil Chemotaxis

(2015) M. F. Ali et al.   JOURNAL OF IMMUNOLOGY

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation

(2015) Jong-Seok Moon et al.   Cell Reports

Cutting Edge: Alum Adjuvant Stimulates Inflammatory Dendritic Cells through Activation of the NALP3 Inflammasome

(2014) M. Kool et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Inflammasome Activation by Alum and Alum's Adjuvant Effect Are Mediated by NLRP3

(2014) H. Li et al.   JOURNAL OF IMMUNOLOGY

IL1B and DEFB1 Polymorphisms Increase Susceptibility to Invasive Mold Infection After Solid-Organ Transplantation

(2014) A. Wojtowicz et al.   JOURNAL OF INFECTIOUS DISEASES

Adaptive Immunity to Fungi

(2014) A. Verma et al.   Cold Spring Harbor Perspectives in Medicine

The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus

(2013) Rachael Keating et al.   NATURE IMMUNOLOGY

Glycosphingolipids MediatePneumocystisCell Wall β-Glucan Activation of the IL-23/IL-17 Axis in Human Dendritic Cells

(2012) Eva M. Carmona et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

Regulation of Immune Responses by mTOR

(2012) Jonathan D. Powell et al.   Annual Review of Immunology

Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome

(2012) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Akt and mTOR in B Cell Activation and Differentiation

(2012) Jose J. Limon et al.   Frontiers in Immunology

Direct activation of mTOR in B lymphocytes confers impairment in B-cell maturation andloss of marginal zone B cells

(2011) Sandrine Benhamron et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human peripheral blood B-cell compartments: A crossroad in B-cell traffic

(2010) M. Perez-Andres et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Proteoglycans in health and disease: the multiple roles of syndecan shedding

(2010) Tina Manon-Jensen et al.   FEBS Journal

(1,3)- -Glucans Activate Both Dectin-1 and NLRP3 Inflammasome in Human Macrophages

(2010) P. Kankkunen et al.   JOURNAL OF IMMUNOLOGY

IL-1β Processing in Host Defense: Beyond the Inflammasomes

(2010) Mihai G. Netea et al.   PLoS Pathogens

An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans

(2009) Amy G. Hise et al.   Cell Host & Microbe

Involvement of the NLRP3 Inflammasome in Innate and Humoral Adaptive Immune Responses to Fungal  -Glucan

(2009) H. Kumar et al.   JOURNAL OF IMMUNOLOGY

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

(2009) Olaf Gross et al.   NATURE

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-κB activation through Raf-1 and Syk

(2009) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Cytokine-producing B lymphocytes—key regulators of immunity

(2008) Frances E Lund   CURRENT OPINION IN IMMUNOLOGY

Toll-Like Receptor 9-Dependent Immune Activation by Unmethylated CpG Motifs in Aspergillus fumigatus DNA

(2008) Z. G. Ramirez-Ortiz et al.   INFECTION AND IMMUNITY

IL1 Gene Cluster Polymorphisms and Its Haplotypes may Predict the Risk to Develop Invasive Pulmonary Aspergillosis and Modulate C-reactive Protein Level

(2008) J. Sainz et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Evidence that cytokines play a role in rheumatoid arthritis

(2008) Fionula M. Brennan et al.   JOURNAL OF CLINICAL INVESTIGATION

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

(2008) Stephanie C. Eisenbarth et al.   NATURE

Toll-like receptor–mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

(2008) Weiping Cao et al.   NATURE IMMUNOLOGY