标题
Ribonucleotide reductase and cancer: biological mechanisms and targeted therapies
作者
关键词
-
出版物
ONCOGENE
Volume 34, Issue 16, Pages 2011-2021
出版商
Springer Nature
发表日期
2014-06-09
DOI
10.1038/onc.2014.155
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ribonucleotide reductase and thymidylate synthase or exogenous deoxyribonucleosides reduce DNA damage and senescence caused by C-MYC depletion
- (2016) Sudha Mannava et al. Aging-US
- Fludarabine phosphate for the first-line treatment of chronic lymphocytic leukaemia
- (2014) S Walker et al. HEALTH TECHNOLOGY ASSESSMENT
- Response to First-Line Chemotherapy in Patients with Non-Small Cell Lung Cancer According to RRM1 Expression
- (2014) Xiaopeng Dong et al. PLoS One
- Reversible, Long-Range Radical Transfer in E. coli Class Ia Ribonucleotide Reductase
- (2013) Ellen C. Minnihan et al. ACCOUNTS OF CHEMICAL RESEARCH
- Uncoupling of Allosteric and Oligomeric Regulation in a Functional Hybrid Enzyme Constructed from Escherichia coli and Human Ribonucleotide Reductase
- (2013) Yuan Fu et al. BIOCHEMISTRY
- Gene aberrations of RRM1 and RRM2B and outcome of advanced breast cancer after treatment with docetaxel with or without gemcitabine
- (2013) Charlotte LT Jørgensen et al. BMC CANCER
- Identification of ribonucleotide reductase M2 as a potential target for pro-senescence therapy in epithelial ovarian cancer
- (2013) Katherine M Aird et al. CELL CYCLE
- A 12-Gene Set Predicts Survival Benefits from Adjuvant Chemotherapy in Non-Small Cell Lung Cancer Patients
- (2013) H. Tang et al. CLINICAL CANCER RESEARCH
- Ribonucleotide Reductase Association with Mammalian Liver Mitochondria
- (2013) Korakod Chimploy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Replication stress links structural and numerical cancer chromosomal instability
- (2013) Rebecca A. Burrell et al. NATURE
- Hypermutability and error catastrophe due to defects in ribonucleotide reductase
- (2013) D. Ahluwalia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Suppression of Nucleotide Metabolism Underlies the Establishment and Maintenance of Oncogene-Induced Senescence
- (2013) Katherine M. Aird et al. Cell Reports
- Depletion of Deoxyribonucleotide Pools Is an Endogenous Source of DNA Damage in Cells Undergoing Oncogene-Induced Senescence
- (2012) Sudha Mannava et al. AMERICAN JOURNAL OF PATHOLOGY
- An analysis of human equilibrative nucleoside transporter-1, ribonucleoside reductase subunit M1, ribonucleoside reductase subunit M2, and excision repair cross-complementing gene-1 expression in patients with resected pancreas adenocarcinoma
- (2012) Sarah B. Fisher et al. CANCER
- Silencing of ribonucleotide reductase subunit M1 potentiates the antitumor activity of gemcitabine in resistant cancer cells
- (2012) Piyanuch Wonganan et al. CANCER BIOLOGY & THERAPY
- Sensitizing Cancer Cells: Is It Really All about U?
- (2012) Patrick J. Stover et al. CANCER CELL
- Tumor Cells Require Thymidylate Kinase to Prevent dUTP Incorporation during DNA Repair
- (2012) Chun-Mei Hu et al. CANCER CELL
- Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
- (2012) Patrick S. Ward et al. CANCER CELL
- Cyclin F-Mediated Degradation of Ribonucleotide Reductase M2 Controls Genome Integrity and DNA Repair
- (2012) Vincenzo D'Angiolella et al. CELL
- A molecular view on signal transduction by the apoptosome
- (2012) Thomas F. Reubold et al. CELLULAR SIGNALLING
- Clofarabine Targets the Large Subunit (α) of Human Ribonucleotide Reductase in Live Cells by Assembly into Persistent Hexamers
- (2012) Yimon Aye et al. CHEMISTRY & BIOLOGY
- Ribonucleotide reductase small subunit M2 serves as a prognostic biomarker and predicts poor survival of colorectal cancers
- (2012) Xiyong Liu et al. CLINICAL SCIENCE
- Mechanistic Studies of Semicarbazone Triapine Targeting Human Ribonucleotide Reductasein Vitroand in Mammalian Cells
- (2012) Yimon Aye et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Serine Hydroxymethyltransferase Anchorsde NovoThymidylate Synthesis Pathway to Nuclear Lamina for DNA Synthesis
- (2012) Donald D. Anderson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Systemic delivery of siRNA nanoparticles targeting RRM2 suppresses head and neck tumor growth
- (2012) Mohammad Aminur Rahman et al. JOURNAL OF CONTROLLED RELEASE
- p53R2 is a prognostic factor of melanoma and regulates proliferation and chemosensitivity of melanoma cells
- (2012) Shigeto Matsushita et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Mammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cells
- (2012) G. Pontarin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Emerging roles of the ribonucleotide reductase M2 in colorectal cancer and ultraviolet-induced DNA damage repair
- (2012) Ai-Guo Lu WORLD JOURNAL OF GASTROENTEROLOGY
- Class I Ribonucleotide Reductases: Metallocofactor Assembly and Repair In Vitro and In Vivo
- (2011) Joseph A. Cotruvo et al. Annual Review of Biochemistry
- Ribonucleotide Reductase Small Subunit M2B Prognoses Better Survival in Colorectal Cancer
- (2011) X. Liu et al. CANCER RESEARCH
- Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development
- (2011) Assaf C. Bester et al. CELL
- DNA building blocks: keeping control of manufacture
- (2011) Anders Hofer et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Association of RRM1 –37A>C polymorphism with clinical outcome in colorectal cancer patients treated with gemcitabine-based chemotherapy
- (2011) J. Rodriguez et al. EUROPEAN JOURNAL OF CANCER
- Ribonucleotide reductase inhibition by metal complexes of Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone): A combined experimental and theoretical study
- (2011) Ana Popović-Bijelić et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- RRM1 expression and clinical outcome of gemcitabine-containing chemotherapy for advanced non-small-cell lung cancer: A meta-analysis
- (2011) Weiyi Gong et al. LUNG CANCER
- Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization
- (2011) James Wesley Fairman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Clofarabine 5'-di and -triphosphates inhibit human ribonucleotide reductase by altering the quaternary structure of its large subunit
- (2011) Y. Aye et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Increase in dNTP pool size during the DNA damage response plays a key role in spontaneous and induced-mutagenesis in Escherichia coli
- (2011) S. Gon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Staurosporine increases toxicity of gemcitabine in non-small cell lung cancer cells: role of protein kinase C, deoxycytidine kinase and ribonucleotide reductase
- (2010) Jennifer Sigmond et al. ANTI-CANCER DRUGS
- Beyond hairy cell: the activity of cladribine in other hematologic malignancies
- (2010) D. S. Sigal et al. BLOOD
- Break-induced ATR and Ddb1-Cul4Cdt2 ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast
- (2010) J. Moss et al. GENES & DEVELOPMENT
- Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase
- (2010) H. Niida et al. GENES & DEVELOPMENT
- Ribonucleotide reductase M2 subunit is a novel diagnostic marker and a potential therapeutic target in bladder cancer
- (2010) Teppei Morikawa et al. HISTOPATHOLOGY
- Expression of ribonucleotide reductase M2 subunit in gastric cancer and effects of RRM2 inhibition in vitro
- (2010) Teppei Morikawa et al. HUMAN PATHOLOGY
- The ribonucleotide reductase large subunit (RRM1) as a predictive factor in patients with cancer
- (2010) Lars Petter Jordheim et al. LANCET ONCOLOGY
- MicroRNAs involvement in fludarabine refractory chronic lymphocytic leukemia
- (2010) Manuela Ferracin et al. Molecular Cancer
- Regulation by degradation, a cellular defense against deoxyribonucleotide pool imbalances
- (2010) Chiara Rampazzo et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- siRNA delivery systems for cancer treatment
- (2009) Yu-Kyoung Oh et al. ADVANCED DRUG DELIVERY REVIEWS
- A Heterozygous Truncating Mutation in RRM2B Causes Autosomal-Dominant Progressive External Ophthalmoplegia with Multiple mtDNA Deletions
- (2009) Henna Tyynismaa et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Phase II study of 3-AP Triapine in patients with recurrent or metastatic head and neck squamous cell carcinoma
- (2009) C. M. Nutting et al. ANNALS OF ONCOLOGY
- Thioredoxins and Glutaredoxins: Unifying Elements in Redox Biology
- (2009) Yves Meyer et al. Annual Review of Genetics
- Mitochondrial Neurogastrointestinal Encephalopathy Due to Mutations in RRM2B
- (2009) Aziz Shaibani et al. ARCHIVES OF NEUROLOGY
- Inhibitory mechanisms of heterocyclic carboxaldehyde thiosemicabazones for two forms of human ribonucleotide reductase
- (2009) Lijun Zhu et al. BIOCHEMICAL PHARMACOLOGY
- Expression of nucleoside transporters, deoxycitidine kinase, ribonucleotide reductase regulatory subunits, and gemcitabine catabolic enzymes in primary ovarian cancer
- (2009) Gabriella Ferrandina et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Activity of ribonucleotide reductase helps determine how cells repair DNA double strand breaks
- (2009) Martin D. Burkhalter et al. DNA REPAIR
- Implication of Checkpoint Kinase-dependent Up-regulation of Ribonucleotide Reductase R2 in DNA Damage Response
- (2009) Yong-Wei Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Randomized Phase III Trial of Gemcitabine-Based Chemotherapy With In Situ RRM1 and ERCC1 Protein Levels for Response Prediction in Non–Small-Cell Lung Cancer
- (2009) Craig Reynolds et al. JOURNAL OF CLINICAL ONCOLOGY
- Overexpression of RRM2 decreases thrombspondin-1 and increases VEGF production in human cancer cells in vitro and in vivo: implication of RRM2 in angiogenesis
- (2009) Keqiang Zhang et al. Molecular Cancer
- A novel homozygous RRM2B missense mutation in association with severe mtDNA depletion
- (2009) Gittan Kollberg et al. NEUROMUSCULAR DISORDERS
- Significance of RRM1 and ERCC1 expression in resectable pancreatic adenocarcinoma
- (2009) H Akita et al. ONCOGENE
- Broad Overexpression of Ribonucleotide Reductase Genes in Mice Specifically Induces Lung Neoplasms
- (2008) X. Xu et al. CANCER RESEARCH
- Nucleic Acids as Therapeutic Agents
- (2008) Luis Alvarez-Salas CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Identification of pathways controlling DNA damage induced mutation in Saccharomyces cerevisiae
- (2008) Ewa T. Lis et al. DNA REPAIR
- Clinical Efficacy and Predictive Molecular Markers of Neoadjuvant Gemcitabine and Pemetrexed in Resectable Non-small Cell Lung Cancer
- (2008) Gerold Bepler et al. Journal of Thoracic Oncology
- Drug delivery of siRNA therapeutics: potentials and limits of nanosystems
- (2008) Daniela Reischl et al. Nanomedicine-Nanotechnology Biology and Medicine
- Replication fork movement sets chromatin loop size and origin choice in mammalian cells
- (2008) Sylvain Courbet et al. NATURE
- Upregulation of the p53R2 ribonucleotide reductase subunit by nitric oxide
- (2008) Olivier Guittet et al. NITRIC OXIDE-BIOLOGY AND CHEMISTRY
- Evidence for lesion bypass by yeast replicative DNA polymerases during DNA damage
- (2008) Nasim Sabouri et al. NUCLEIC ACIDS RESEARCH
- Ribonucleotide reductase small subunit p53R2 promotes oral cancer invasion via the E-cadherin/β-catenin pathway
- (2008) Souichi Yanamoto et al. ORAL ONCOLOGY
- ATM-mediated serine 72 phosphorylation stabilizes ribonucleotide reductase small subunit p53R2 protein against MDM2 to DNA damage
- (2008) L. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage
- (2008) G. Pontarin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now