Plastic and Neuroprotective Mechanisms Involved in the Therapeutic Effects of Cannabidiol in Psychiatric Disorders

Natural Cannabinoids Improve Dopamine Neurotransmission and Tau and Amyloid Pathology in a Mouse Model of Tauopathy

(2018) Maria J. Casarejos et al.   JOURNAL OF ALZHEIMERS DISEASE

Cannabis-Based Medicine Reduces Multiple Pathological Processes in AβPP/PS1 Mice

(2018) Ester Aso et al.   JOURNAL OF ALZHEIMERS DISEASE

ABSTRACTS SCANDINAVIAN COLLEGE OF NEUROPSYCHOPHARMACOLOGY SCNP 57th Annual Meeting, April 27th – 29th, 2016 Aarhus, Denmark

(2016)   ACTA NEUROPSYCHIATRICA

The infralimbic and prelimbic medial prefrontal cortices have differential functions in the expression of anxiety-like behaviors in mice

(2016) Satoshi Suzuki et al.   BEHAVIOURAL BRAIN RESEARCH

Antidepressant-like effect of cannabidiol injection into the ventral medial prefrontal cortex—Possible involvement of 5-HT1A and CB1 receptors

(2016) A.G. Sartim et al.   BEHAVIOURAL BRAIN RESEARCH

At the Tip of an Iceberg: Prenatal Marijuana and Its Possible Relation to Neuropsychiatric Outcome in the Offspring

(2016) Alán Alpár et al.   BIOLOGICAL PSYCHIATRY

Oxidative and nitrosative stress pathways in the brain of socially isolated adult male rats demonstrating depressive- and anxiety-like symptoms

(2016) Dragana Filipović et al.   Brain Structure & Function

ICD and DSM: neuroplasticity and staging are still missing

(2016) Stefano Pallanti   CNS SPECTRUMS

The 5-HT1A receptor in Major Depressive Disorder

(2016) Joshua Kaufman et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Cannabidiol Post-Treatment Alleviates Rat Epileptic-Related Behaviors and Activates Hippocampal Cell Autophagy Pathway Along with Antioxidant Defense in Chronic Phase of Pilocarpine-Induced Seizure

(2016) Mahshid Hosseinzadeh et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells

(2016) Ewa Kozela et al.   Journal of Neuroinflammation

A double-blind, randomized, cross-over, placebo-controlled, pilot trial with Sativex in Huntington’s disease

(2016) Jose Luis López-Sendón Moreno et al.   JOURNAL OF NEUROLOGY

Cannabidiol Counteracts Amphetamine-Induced Neuronal and Behavioral Sensitization of the Mesolimbic Dopamine Pathway through a Novel mTOR/p70S6 Kinase Signaling Pathway

(2016) Justine Renard et al.   JOURNAL OF NEUROSCIENCE

Maternal immune activation leads to selective functional deficits in offspring parvalbumin interneurons

(2016) S Canetta et al.   MOLECULAR PSYCHIATRY

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

(2016) Ronald S Duman et al.   NATURE MEDICINE

Keep off the grass? Cannabis, cognition and addiction

(2016) H. Valerie Curran et al.   NATURE REVIEWS NEUROSCIENCE

Impact of DNMT1 and DNMT3a forebrain knockout on depressive- and anxiety like behavior in mice

(2016) Michael J. Morris et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors

(2016) Raquel Linge et al.   NEUROPHARMACOLOGY

Prohedonic Effect of Cannabidiol in a Rat Model of Depression

(2016) Gal Shoval et al.   NEUROPSYCHOBIOLOGY

Cannabidiol, neuroprotection and neuropsychiatric disorders

(2016) Alline C. Campos et al.   PHARMACOLOGICAL RESEARCH

From Phytocannabinoids to Cannabinoid Receptors and Endocannabinoids: Pleiotropic Physiological and Pathological Roles Through Complex Pharmacology

(2016) Alessia Ligresti et al.   PHYSIOLOGICAL REVIEWS

Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects

(2016) Aviva Breuer et al.   PLoS One

Influence of single and repeated cannabidiol administration on emotional behavior and markers of cell proliferation and neurogenesis in non-stressed mice

(2016) Angélica Pupin Schiavon et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Redox dysregulation, neuroinflammation, and NMDA receptor hypofunction: A “central hub” in schizophrenia pathophysiology?

(2016) P. Steullet et al.   SCHIZOPHRENIA RESEARCH

VCE-003.2, a novel cannabigerol derivative, enhances neuronal progenitor cell survival and alleviates symptomatology in murine models of Huntington’s disease

(2016) Javier Díaz-Alonso et al.   Scientific Reports

ABSTRACTS SCANDINAVIAN COLLEGE OF NEUROPSYCHOPHARMACOLOGY SCNP 57th Annual Meeting, April 27th – 29th, 2016 Aarhus, Denmark

(2016)   ACTA NEUROPSYCHIATRICA

CREB-mediated synaptogenesis and neurogenesis is crucial for the role of 5-HT1a receptors in modulating anxiety behaviors

(2016) Jing Zhang et al.   Scientific Reports

Prolonged Period of Cortical Plasticity upon Redox Dysregulation in Fast-Spiking Interneurons

(2015) Hirofumi Morishita et al.   BIOLOGICAL PSYCHIATRY

Are cannabidiol and Δ9-tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review

(2015) John M McPartland et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor

(2015) R B Laprairie et al.   BRITISH JOURNAL OF PHARMACOLOGY

Hippocampal Neurogenesis, Neurotrophic Factors and Depression: Possible Therapeutic Targets?

(2015) Gianluca Serafini et al.   CNS & Neurological Disorders-Drug Targets

The role of antioxidants in the chemistry of oxidative stress: A review

(2015) Aurelia Magdalena Pisoschi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cannabidiol Attenuates Sensorimotor Gating Disruption and Molecular Changes Induced by Chronic Antagonism of NMDA receptors in Mice

(2015) Felipe V. Gomes et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Fatty Acid-binding Proteins (FABPs) Are Intracellular Carriers for Δ9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD)

(2015) Matthew W. Elmes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

5-HT1A receptors on mature dentate gyrus granule cells are critical for the antidepressant response

(2015) Benjamin Adam Samuels et al.   NATURE NEUROSCIENCE

Cannabidiol increases survival and promotes rescue of cognitive function in a murine model of cerebral malaria

(2015) A.C. Campos et al.   NEUROSCIENCE

Molecular Targets of Cannabidiol in Neurological Disorders

(2015) Clementino Ibeas Bih et al.   Neurotherapeutics

mTOR in Brain Physiology and Pathologies

(2015) Joël Bockaert et al.   PHYSIOLOGICAL REVIEWS

Prenatal exposure to cannabinoids evokes long-lasting functional alterations by targeting CB1receptors on developing cortical neurons

(2015) Adán de Salas-Quiroga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cannabidiol effects in the prepulse inhibition disruption induced by amphetamine

(2015) J. F. C. Pedrazzi et al.   PSYCHOPHARMACOLOGY

Decreased glial reactivity could be involved in the antipsychotic-like effect of cannabidiol

(2015) Felipe V. Gomes et al.   SCHIZOPHRENIA RESEARCH

The neuroprotection of cannabidiol against MPP + -induced toxicity in PC12 cells involves trkA receptors, upregulation of axonal and synaptic proteins, neuritogenesis, and might be relevant to Parkinson's disease

(2015) Neife Aparecida Guinaim Santos et al.   TOXICOLOGY IN VITRO

Molecular network of neuronal autophagy in the pathophysiology and treatment of depression

(2015) Jack Jia et al.   Neuroscience Bulletin

Nonpsychotropic Plant Cannabinoids, Cannabidivarin (CBDV) and Cannabidiol (CBD), Activate and Desensitize Transient Receptor Potential Vanilloid 1 (TRPV1) Channels in Vitro: Potential for the Treatment of Neuronal Hyperexcitability

(2014) Fabio Arturo Iannotti et al.   ACS Chemical Neuroscience

Cannabinoid-induced autophagy regulates suppressor of cytokine signaling-3 in intestinal epithelium

(2014) Luan C. Koay et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Increased expression of astrocyte markers in schizophrenia: Association with neuroinflammation

(2014) Vibeke Sørensen Catts et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Maternal exposure to fluoxetine during gestation and lactation affects the DNA methylation programming of rat's offspring: Modulation by folic acid supplementation

(2014) L.V. Toffoli et al.   BEHAVIOURAL BRAIN RESEARCH

Miswiring the brain:  9-tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin-2 degradation pathway

(2014) G. Tortoriello et al.   EMBO JOURNAL

Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

(2014) Orrin Devinsky et al.   EPILEPSIA

Cannabidiol protects liver from binge alcohol-induced steatosis by mechanisms including inhibition of oxidative stress and increase in autophagy

(2014) Lili Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cannabidiol Exposure During Neuronal Differentiation Sensitizes Cells Against Redox-Active Neurotoxins

(2014) Patrícia Schönhofen et al.   MOLECULAR NEUROBIOLOGY

The role of DNA methylation in stress-related psychiatric disorders

(2014) Torsten Klengel et al.   NEUROPHARMACOLOGY

Neuroprotective Properties of Cannabigerol in Huntington’s Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice

(2014) Sara Valdeolivas et al.   Neurotherapeutics

Protective Effects of Cannabidiol Against Hippocampal Cell Death and Cognitive Impairment Induced by Bilateral Common Carotid Artery Occlusion in Mice

(2014) Angélica Pupin Schiavon et al.   NEUROTOXICITY RESEARCH

A ventral view on antidepressant action: roles for adult hippocampal neurogenesis along the dorsoventral axis

(2014) Olivia F. O’Leary et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans

(2014) Nils C. Gassen et al.   PLOS MEDICINE

Adult Neuroplasticity: More Than 40 Years of Research

(2014) Eberhard Fuchs et al.   NEURAL PLASTICITY

Effects of cannabinoid drugs on the deficit of prepulse inhibition of startle in an animal model of schizophrenia: the SHR strain

(2014) Raquel Levin et al.   Frontiers in Pharmacology

Epigenetic control of skin differentiation genes by phytocannabinoids

(2013) Mariangela Pucci et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabinoid Effects on β Amyloid Fibril and Aggregate Formation, Neuronal and Microglial-Activated Neurotoxicity In Vitro

(2013) Emelie Janefjord et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Cannabinoids, Neurogenesis and Antidepressant Drugs: Is there a Link?

(2013) Manoela Viar Fogaca et al.   Current Neuropharmacology

Neuroprotection and reduction of glial reaction by cannabidiol treatment after sciatic nerve transection in neonatal rats

(2013) Matheus Perez et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Effects of intra-prelimbic prefrontal cortex injection of cannabidiol on anxiety-like behavior: Involvement of 5HT1A receptors and previous stressful experience

(2013) M.V. Fogaça et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system

(2013) Alline C. Campos et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The Dynamic Brain: Neuroplasticity and Mental Health

(2013) Jill L. Kays et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

The role of 5-HT1A receptors in the anti-aversive effects of cannabidiol on panic attack-like behaviors evoked in the presence of the wild snake Epicrates cenchria crassus (Reptilia, Boidae)

(2013) André Twardowschy et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Cannabidiol Normalizes Caspase 3, Synaptophysin, and Mitochondrial Fission Protein DNM1L Expression Levels in Rats with Brain Iron Overload: Implications for Neuroprotection

(2013) Vanessa Kappel da Silva et al.   MOLECULAR NEUROBIOLOGY

Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: A role for A2A receptors

(2013) M. Mecha et al.   NEUROBIOLOGY OF DISEASE

Motor effects of the non-psychotropic phytocannabinoid cannabidiol that are mediated by 5-HT1A receptors

(2013) Francisco Espejo-Porras et al.   NEUROPHARMACOLOGY

Mechanisms of cannabidiol neuroprotection in hypoxic–ischemic newborn pigs: Role of 5HT1A and CB2 receptors

(2013) M. Ruth Pazos et al.   NEUROPHARMACOLOGY

Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects

(2013) Ian Mahar et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Cannabidiol Promotes Amyloid Precursor Protein Ubiquitination and Reduction of Beta Amyloid Expression in SHSY5YAPP+Cells Through PPARγ Involvement

(2013) Caterina Scuderi et al.   PHYTOTHERAPY RESEARCH

Cannabidiol, a Non-Psychoactive Cannabinoid Compound, Inhibits Proliferation and Invasion in U87-MG and T98G Glioma Cells through a Multitarget Effect

(2013) Marta Solinas et al.   PLoS One

Sativex-like Combination of Phytocannabinoids is Neuroprotective in Malonate-Lesioned Rats, an Inflammatory Model of Huntington’s Disease: Role of CB1 and CB2 Receptors

(2012) Sara Valdeolivas et al.   ACS Chemical Neuroscience

Cannabidiol inhibits the reward-facilitating effect of morphine: involvement of 5-HT1Areceptors in the dorsal raphe nucleus

(2012) Vicky Katsidoni et al.   ADDICTION BIOLOGY

Is unpredictable chronic mild stress (UCMS) a reliable model to study depression-induced neuroinflammation?

(2012) Rai Khalid Farooq et al.   BEHAVIOURAL BRAIN RESEARCH

Antidepressants inhibit DNA methyltransferase 1 through reducing G9a levels

(2012) Nicole Zimmermann et al.   BIOCHEMICAL JOURNAL

Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?

(2012) Javier Fernández-Ruiz et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

A Cannabigerol Quinone Alleviates Neuroinflammation in a Chronic Model of Multiple Sclerosis

(2012) Aitor G. Granja et al.   Journal of Neuroimmune Pharmacology

Cannabidiol blocks long-lasting behavioral consequences of predator threat stress: Possible involvement of 5HT1A receptors

(2012) Alline Cristina Campos et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Cannabidiol and clozapine reverse MK-801-induced deficits in social interaction and hyperactivity in Sprague–Dawley rats

(2012) Anand Gururajan et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro

(2012) Benjamin S. Harvey et al.   NEUROTOXICOLOGY

Endocannabinoids via CB1 receptors act as neurogenic niche cues during cortical development

(2012) J. Diaz-Alonso et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders

(2012) A. C. Campos et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Distinct Neurobehavioural Effects of Cannabidiol in Transmembrane Domain Neuregulin 1 Mutant Mice

(2012) Leonora E. Long et al.   PLoS One

Involvement of serotonin-mediated neurotransmission in the dorsal periaqueductal gray matter on cannabidiol chronic effects in panic-like responses in rats

(2012) Alline Cristina Campos et al.   PSYCHOPHARMACOLOGY

NMDA Receptor Hypofunction, Parvalbumin-Positive Neurons, and Cortical Gamma Oscillations in Schizophrenia

(2012) G. Gonzalez-Burgos et al.   SCHIZOPHRENIA BULLETIN

Cannabidiol protects oligodendrocyte progenitor cells from inflammation-induced apoptosis by attenuating endoplasmic reticulum stress

(2012) M Mecha et al.   Cell Death & Disease

Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia

(2012) F M Leweke et al.   Translational Psychiatry

Administration of cannabidiol and imipramine induces antidepressant-like effects in the forced swimming test and increases brain-derived neurotrophic factor levels in the rat amygdala.

(2011) Gislaine Z. Réus et al.   ACTA NEUROPSYCHIATRICA

Antidepressant-like effect induced by systemic and intra-hippocampal administration of DNA methylation inhibitors

(2011) Amanda J Sales et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT1A somatodendritic autoreceptors in the dorsal raphe nucleus

(2011) EM Rock et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington's disease

(2011) Onintza Sagredo et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cannabidiol and Other Cannabinoids Reduce Microglial Activation In Vitro and In Vivo: Relevance to Alzheimer's Disease

(2011) A. M. Martin-Moreno et al.   MOLECULAR PHARMACOLOGY

Adult hippocampal neurogenesis buffers stress responses and depressive behaviour

(2011) Jason S. Snyder et al.   NATURE

GABAergic interneuron origin of schizophrenia pathophysiology

(2011) Kazu Nakazawa et al.   NEUROPHARMACOLOGY

Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients

(2011) Mateus M Bergamaschi et al.   NEUROPSYCHOPHARMACOLOGY

Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement

(2011) Giuseppe Esposito et al.   PLoS One

Anxiogenic-like effects of chronic cannabidiol administration in rats

(2011) Maha M. ElBatsh et al.   PSYCHOPHARMACOLOGY

Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors

(2010) Vanessa de Paula Soares et al.   BEHAVIOURAL BRAIN RESEARCH

Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors

(2010) Plinio C. Casarotto et al.   BEHAVIOURAL PHARMACOLOGY

Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis

(2010) Sean D. McAllister et al.   BREAST CANCER RESEARCH AND TREATMENT

Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation

(2010) I Magen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice

(2010) Y Avraham et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effects of cannabinoids and cannabinoid-enrichedCannabisextracts on TRP channels and endocannabinoid metabolic enzymes

(2010) Luciano De Petrocellis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis

(2010) Susanne A Wolf et al.   Cell Communication and Signaling

Diminished gray matter in the hippocampus of cannabis users: Possible protective effects of cannabidiol

(2010) Traute Demirakca et al.   DRUG AND ALCOHOL DEPENDENCE

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

(2010) Wei Deng et al.   NATURE REVIEWS NEUROSCIENCE

Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?

(2010) Michael S. Fanselow et al.   NEURON

Antidepressant-like effect of Δ9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L.

(2010) Abir T. El-Alfy et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors

(2010) Felipe V. Gomes et al.   PSYCHOPHARMACOLOGY

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Assessment of Pharmacotherapy for Negative Symptoms of Schizophrenia

(2010) Elizabeth Hanson et al.   Current Psychiatry Reports

Signaling in Adult Neurogenesis

(2009) Hoonkyo Suh et al.   Annual Review of Cell and Developmental Biology

Distinct Effects of Δ9-Tetrahydrocannabinol and Cannabidiol on Neural Activation During Emotional Processing

(2009) Paolo Fusar-Poli et al.   ARCHIVES OF GENERAL PSYCHIATRY

5-HT1Areceptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats

(2009) Leonardo B.M. Resstel et al.   BRITISH JOURNAL OF PHARMACOLOGY

Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors

(2009) TV Zanelati et al.   BRITISH JOURNAL OF PHARMACOLOGY

Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action☆

(2009) P.J. Lucassen et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Modulation of effective connectivity during emotional processing by Δ9-tetrahydrocannabinol and cannabidiol

(2009) Paolo Fusar-Poli et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Cannabinoids Δ9-Tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-activated NF-κB and Interferon-β/STAT Proinflammatory Pathways in BV-2 Microglial Cells

(2009) Ewa Kozela et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lithium induces clearance of protease resistant prion protein in prion-infected cells by induction of autophagy

(2009) Andreas Heiseke et al.   JOURNAL OF NEUROCHEMISTRY

Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania

(2009) Samira S Valvassori et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Long-Term Fluoxetine Treatment Modulates Cannabinoid Type 1 Receptor-Mediated Inhibition of Adenylyl Cyclase in the Rat Prefrontal Cortex through 5-Hydroxytryptamine1A Receptor-Dependent Mechanisms

(2009) S. Mato et al.   MOLECULAR PHARMACOLOGY

The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic–ischemic brain damage in mice is mediated by CB2 and adenosine receptors

(2009) A. Castillo et al.   NEUROBIOLOGY OF DISEASE

Neurogenesis-Dependent and -Independent Effects of Fluoxetine in an Animal Model of Anxiety/Depression

(2009) Denis J. David et al.   NEURON

Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology

(2009) Sagnik Bhattacharyya et al.   NEUROPSYCHOPHARMACOLOGY

Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids

(2009) Alline Cristina Campos et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb

(2009) Angelo A. Izzo et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Neural Basis of Δ-9-Tetrahydrocannabinol and Cannabidiol: Effects During Response Inhibition

(2008) Stefan J. Borgwardt et al.   BIOLOGICAL PSYCHIATRY

Epigenetic mechanisms in mammals

(2008) J. K. Kim et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Antioxidants and Neuroprotection in the Adult and Developing Central Nervous System

(2008) Charanjit Kaur et al.   CURRENT MEDICINAL CHEMISTRY

Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death

(2008) H. Pan et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling

(2008) J M Bessa et al.   MOLECULAR PSYCHIATRY

The molecular neurobiology of depression

(2008) Vaishnav Krishnan et al.   NATURE

Decoding the Epigenetic Language of Neuronal Plasticity

(2008) Emiliana Borrelli et al.   NEURON

Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats

(2008) Alline Cristina Campos et al.   PSYCHOPHARMACOLOGY

The neurogenic reserve hypothesis: what is adult hippocampal neurogenesis good for?

(2008) Gerd Kempermann   TRENDS IN NEUROSCIENCES

Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression

(2007) G Esposito et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro

(2007) A Thomas et al.   BRITISH JOURNAL OF PHARMACOLOGY