PMEL: a pigment cell-specific model for functional amyloid formation

MHC Class II Presentation of gp100 Epitopes in Melanoma Cells Requires the Function of Conventional Endosomes and Is Influenced by Melanosomes

(2014) V. Robila et al.   JOURNAL OF IMMUNOLOGY

Interaction ofMC1RandPMELalleles on solid coat colors in Highland cattle

(2012) Sheila M. Schmutz et al.   ANIMAL GENETICS

Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory

(2012) Amitabha Majumdar et al.   CELL

The Melanosomal Protein PMEL17 as a Target for Antibody Drug Conjugate Therapy in Melanoma

(2012) Youjun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association Analyses Identify Three Susceptibility Loci for Vitiligo in the Chinese Han Population

(2012) Xian-Fa Tang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A Molecular History of the Amyloidoses

(2012) Joel N. Buxbaum et al.   JOURNAL OF MOLECULAR BIOLOGY

Synchronization of secretory protein traffic in populations of cells

(2012) Gaelle Boncompain et al.   NATURE METHODS

Mechanisms of Protein Delivery to Melanosomes in Pigment Cells

(2012) Anand Sitaram et al.   PHYSIOLOGY

Multivesicular Body Morphogenesis

(2011) Phyllis I. Hanson et al.   Annual Review of Cell and Developmental Biology

Segmental Polymorphism in a Functional Amyloid

(2011) Kan-Nian Hu et al.   BIOPHYSICAL JOURNAL

MVB vesicle formation: ESCRT-dependent, ESCRT-independent and everything in between

(2011) Markus Babst   CURRENT OPINION IN CELL BIOLOGY

The Tetraspanin CD63 Regulates ESCRT-Independent and -Dependent Endosomal Sorting during Melanogenesis

(2011) Guillaume van Niel et al.   DEVELOPMENTAL CELL

Proprotein Convertases Process Pmel17 during Secretion

(2011) Ralf M. Leonhardt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Matrix Metalloproteinase 3-mediated α-Synuclein Cleavage in Dopaminergic Cell Death

(2011) Dong-Hee Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coat-colour dilution and hypotrichosis in Hereford crossbred calves

(2011) RD Jolly et al.   NEW ZEALAND VETERINARY JOURNAL

Coat color dilution in mice because of inactivation of the melanoma antigen MART-1

(2011) Iraz T. Aydin et al.   Pigment Cell & Melanoma Research

The ocular albinism type 1 (OA1) GPCR is ubiquitinated and its traffic requires endosomal sorting complex responsible for transport (ESCRT) function

(2011) F. Giordano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity, biogenesis and function of microbial amyloids

(2011) Luz P. Blanco et al.   TRENDS IN MICROBIOLOGY

Mutations in or near the Transmembrane Domain Alter PMEL Amyloid Formation from Functional to Pathogenic

(2011) Brenda Watt et al.   PLoS Genetics

Inactivation of Pmel Alters Melanosome Shape But Has Only a Subtle Effect on Visible Pigmentation

(2011) Anders R. Hellström et al.   PLoS Genetics

Physiological functions of the amyloid precursor protein secretases ADAM10, BACE1, and Presenilin

(2011) Johannes Prox et al.   EXPERIMENTAL BRAIN RESEARCH

Repeat Domains of Melanosome Matrix Protein Pmel17 Orthologs Form Amyloid Fibrils at the Acidic Melanosomal pH

(2010) Ryan P. McGlinchey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic Reticulum Export, Subcellular Distribution, and Fibril Formation by Pmel17 Require an Intact N-terminal Domain Junction

(2010) Ralf M. Leonhardt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of pH on aggregation kinetics of the repeat domain of a functional amyloid, Pmel17

(2010) C. M. Pfefferkorn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying the amylome, proteins capable of forming amyloid-like fibrils

(2010) Lukasz Goldschmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biology of Amyloid: Structure, Function, and Regulation

(2010) Jason Greenwald et al.   STRUCTURE

A mutation within the transmembrane domain of melanosomal protein Silver (Pmel17) changes lumenal fragment interactions

(2009) Regina Kuliawat et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The secreted form of a melanocyte membrane-bound glycoprotein (Pmel17/gp100) is released by ectodomain shedding

(2009) Toshihiko Hoashi et al.   FASEB JOURNAL

Competing discrete interfacial effects are critical for amyloidogenesis

(2009) Létitia Jean et al.   FASEB JOURNAL

The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition

(2009) Francesca Giordano et al.   HUMAN MOLECULAR GENETICS

N-terminal Domains Elicit Formation of Functional Pmel17 Amyloid Fibrils

(2009) Brenda Watt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis

(2009) Cédric Delevoye et al.   JOURNAL OF CELL BIOLOGY

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

Current challenges in understanding melanogenesis: bridging chemistry, biological control, morphology, and function

(2009) John D Simon et al.   Pigment Cell & Melanoma Research

The repeat domain of the melanosome fibril protein Pmel17 forms the amyloid core promoting melanin synthesis

(2009) R. P. McGlinchey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules

(2009) S. K. Maji et al.   SCIENCE

ESCRT-I Function is Required for Tyrp1 Transport from Early Endosomes to the Melanosome Limiting Membrane

(2009) Steven T. Truschel et al.   TRAFFIC

Increased α-synuclein aggregation following limited cleavage by certain matrix metalloproteinases

(2008) Johannes Levin et al.   EXPERIMENTAL NEUROLOGY

Formation of Pmel17 Amyloid Is Regulated by Juxtamembrane Metalloproteinase Cleavage, and the Resulting C-terminal Fragment Is a Substrate for γ-Secretase

(2008) Markus P. Kummer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Localization to Mature Melanosomes by Virtue of Cytoplasmic Dileucine Motifs Is Required for Human OCA2 Function

(2008) Anand Sitaram et al.   MOLECULAR BIOLOGY OF THE CELL

Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes

(2008) Subba Rao Gangi Setty et al.   NATURE

Electron tomography of early melanosomes: Implications for melanogenesis and the generation of fibrillar amyloid sheets

(2008) I. Hurbain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA