Mammalian prions and their wider relevance in neurodegenerative diseases

Dura mater is a potential source of Aβ seeds

(2016) Gabor G. Kovacs et al.   ACTA NEUROPATHOLOGICA

Transmissible amyloid

(2016) L.O. Tjernberg et al.   JOURNAL OF INTERNAL MEDICINE

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

A critical appraisal of the pathogenic protein spread hypothesis of neurodegeneration

(2016) Dominic M. Walsh et al.   NATURE REVIEWS NEUROSCIENCE

Ex vivomammalian prions are formed of paired double helical prion protein fibrils

(2016) Cassandra Terry et al.   Open Biology

Clinical Trial Simulations Based on Genetic Stratification and the Natural History of a Functional Outcome Measure in Creutzfeldt-Jakob Disease

(2016) Simon Mead et al.   JAMA Neurology

The Biology of Proteostasis in Aging and Disease

(2015) Johnathan Labbadia et al.   Annual Review of Biochemistry

Rapidly progressive Alzheimer’s disease features distinct structures of amyloid-β

(2015) Mark L. Cohen et al.   BRAIN

Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy

(2015) Zane Jaunmuktane et al.   NATURE

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

(2015) Stanley B. Prusiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled A , tau, and  -synuclein

(2015) M. Goedert   SCIENCE

Creutzfeldt-Jakob disease and blood transfusion: updated results of the UK Transfusion Medicine Epidemiology Review Study

(2015) P. J. M. Urwin et al.   VOX SANGUINIS

Preclinical detection of infectivity and disease-specific PrP in blood throughout the incubation period of prion disease

(2015) Elizabeth B. Sawyer et al.   Scientific Reports

A novel and rapid method for obtaining high titre intact prion strains from mammalian brain

(2015) Adam Wenborn et al.   Scientific Reports

A systematic investigation of production of synthetic prions from recombinant prion protein

(2015) Christian Schmidt et al.   Open Biology

Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS

(2015) Emmanuel A. Asante et al.   PLoS Pathogens

Chronic Wasting Disease of Cervids: Current Knowledge and Future Perspectives

(2015) Nicholas J. Haley et al.   Annual Review of Animal Biosciences

Monoclonal Antibodies against Aβ42 Fibrils Distinguish Multiple Aggregation State Polymorphismsin Vitroand in Alzheimer Disease Brain

(2014) Asa Hatami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-amyloid Compounds Inhibit α-Synuclein Aggregation Induced by Protein Misfolding Cyclic Amplification (PMCA)

(2014) Maria Eugenia Herva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peripheral Administration of a Humanized Anti-PrP Antibody Blocks Alzheimer's Disease A  Synaptotoxicity

(2014) I. Klyubin et al.   JOURNAL OF NEUROSCIENCE

The structure of the infectious prion protein

(2014) Jesús R Requena et al.   Prion

Serial propagation of distinct strains of A  prions from Alzheimer's disease patients

(2014) J. C. Watts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prion neuropathology follows the accumulation of alternate prion protein isoforms after infective titre has peaked

(2014) Malin K. Sandberg et al.   Nature Communications

Detection of Misfolded Aβ Oligomers for Sensitive Biochemical Diagnosis of Alzheimer’s Disease

(2014) Natalia Salvadores et al.   Cell Reports

Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice

(2013) Florence Clavaguera et al.   ACTA NEUROPATHOLOGICA

Prions and the Potential Transmissibility of Protein Misfolding Diseases

(2013) Allison Kraus et al.   Annual Review of Microbiology

Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue

(2013) Jun-Xia Lu et al.   CELL

Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons

(2013) Jing L. Guo et al.   CELL

Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice

(2013) Götz Heilbronner et al.   EMBO REPORTS

Disease characteristics of bovine spongiform encephalopathy following inoculation into mice via three different routes

(2013) Christopher M. Vickery et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Therapeutic effect of peripheral administration of an anti-prion protein antibody on mice infected with prions

(2013) Natsuo Ohsawa et al.   MICROBIOLOGY AND IMMUNOLOGY

The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein

(2013) Tiziana Sonati et al.   NATURE

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

(2013) Mathias Jucker et al.   NATURE

Drug resistance confounding prion therapeutics

(2013) D. B. Berry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain homogenates from human tauopathies induce tau inclusions in mouse brain

(2013) Florence Clavaguera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and functional characterization of two alpha-synuclein strains

(2013) Luc Bousset et al.   Nature Communications

Prevalent abnormal prion protein in human appendixes after bovine spongiform encephalopathy epizootic: large scale survey

(2013) O. N. Gill et al.   BMJ-British Medical Journal

Acquisition of Drug Resistance and Dependence by Prions

(2013) Anja M. Oelschlegel et al.   PLoS Pathogens

Evaluation of Potential Infectivity of Alzheimer and Parkinson Disease Proteins in Recipients of Cadaver-Derived Human Growth Hormone

(2013) David J. Irwin et al.   JAMA Neurology

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

High-resolution structure of infectious prion protein: the final frontier

(2012) Rodrigo Diaz-Espinoza et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lifelong Management of Amyloid-Beta Metabolism to Prevent Alzheimer's Disease

(2012) Sam Gandy   NEW ENGLAND JOURNAL OF MEDICINE

Purified and synthetic Alzheimer's amyloid beta (A ) prions

(2012) J. Stohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of prion infection in variant Creutzfeldt-Jakob disease: a blood-based assay

(2011) Julie Ann Edgeworth et al.   LANCET

De novo induction of amyloid-β deposition in vivo

(2011) R Morales et al.   MOLECULAR PSYCHIATRY

Prion propagation and toxicity in vivo occur in two distinct mechanistic phases

(2011) Malin K. Sandberg et al.   NATURE

Prion diseases of yeast: Amyloid structure and biology

(2011) Reed B. Wickner et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Recombinant prion protein induces a new transmissible prion disease in wild-type animals

(2010) Natallia Makarava et al.   ACTA NEUROPATHOLOGICA

Mammalian Prions Generated from Bacterially Expressed Prion Protein in the Absence of Any Mammalian Cofactors

(2010) Jae-Il Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Preparation and characterization of toxic Aβ aggregates for structural and functional studies in Alzheimer's disease research

(2010) Asad Jan et al.   Nature Protocols

Review: Contribution of transgenic models to understanding human prion disease

(2010) J. D. F. Wadsworth et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Pharmacological chaperone for the structured domain of human prion protein

(2010) Andrew J. Nicoll et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spontaneous generation of mammalian prions

(2010) J. A. Edgeworth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Darwinian Evolution of Prions in Cell Culture

(2010) J. Li et al.   SCIENCE

Prion Strain Mutation and Selection

(2010) J. Collinge   SCIENCE

Generating a Prion with Bacterially Expressed Recombinant Prion Protein

(2010) F. Wang et al.   SCIENCE

Peripherally Applied A -Containing Inoculates Induce Cerebral  -Amyloidosis

(2010) Y. S. Eisele et al.   SCIENCE

Crystal structure of human prion protein bound to a therapeutic antibody

(2009) S. V. Antonyuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of cerebral  -amyloidosis: Intracerebral versus systemic A  inoculation

(2009) Y. S. Eisele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin

(2008) Sabrina Cronier et al.   BIOCHEMICAL JOURNAL

Effect of intraventricular infusion of anti-prion protein monoclonal antibodies on disease progression in prion-infected mice

(2008) C.-H. Song et al.   JOURNAL OF GENERAL VIROLOGY

Surgery and Risk of Sporadic Creutzfeldt-Jakob Disease in Denmark and Sweden: Registry-Based Case-Control Studies

(2008) Ignacio Mahillo-Fernandez et al.   NEUROEPIDEMIOLOGY

Central and peripheral pathology of kuru: pathological analysis of a recent case and comparison with other forms of human prion disease

(2008) S. Brandner et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES