Antidyskinetic Effects of MEK Inhibitor Are Associated with Multiple Neurochemical Alterations in the Striatum of Hemiparkinsonian Rats

Selective Inactivation of Striatal FosB/ΔFosB-Expressing Neurons Alleviates L-DOPA–Induced Dyskinesia

(2016) Michel Engeln et al.   BIOLOGICAL PSYCHIATRY

Dual κ-agonist/μ-antagonist opioid receptor modulation reduces levodopa-induced dyskinesia and corrects dysregulated striatal changes in the nonhuman primate model of Parkinson disease

(2015) Lisa F. Potts et al.   ANNALS OF NEUROLOGY

A Novel Role of Salt-Inducible Kinase 1 (SIK1) in the Post-Translational Regulation of Scavenger Receptor Class B Type 1 Activity

(2015) Zhigang Hu et al.   BIOCHEMISTRY

Evidence for a common biological pathway linking three Parkinson's disease-causing genes:parkin,PINK1andDJ-1

(2015) Celia van der Merwe et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

∆FosB: A transcriptional regulator of stress and antidepressant responses

(2015) Eric J. Nestler   EUROPEAN JOURNAL OF PHARMACOLOGY

Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal Activity

(2015) Takashi Miyamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gene Expression Analyses Identify Narp Contribution in the Development of L-DOPA-Induced Dyskinesia

(2015) F. Charbonnier-Beaupel et al.   JOURNAL OF NEUROSCIENCE

Striatal tyrosine hydroxylase-positive neurons are associated with l-DOPA-induced dyskinesia in hemiparkinsonian mice

(2015) U. Keber et al.   NEUROSCIENCE

Levetiracetam Ameliorates L-DOPA-Induced Dyskinesia in Hemiparkinsonian Rats Inducing Critical Molecular Changes in the Striatum

(2015) Huan Du et al.   Parkinsons Disease

Gastrodia elata Blume alleviates L-DOPA-induced dyskinesia by normalizing FosB and ERK activation in a 6-OHDA-lesioned Parkinson’s disease mouse model

(2014) Ah-Reum Doo et al.   BMC Complementary and Alternative Medicine

Differential distribution of hypoxia-inducible factor 1-beta (ARNT or ARNT2) in mouse substantia nigra and ventral tegmental area

(2014) J.A.D. Dela Cruz et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Threonine 149 Phosphorylation Enhances  FosB Transcriptional Activity to Control Psychomotor Responses to Cocaine

(2014) H. M. Cates et al.   JOURNAL OF NEUROSCIENCE

D1R/GluN1 complexes in the striatum integrate dopamine and glutamate signalling to control synaptic plasticity and cocaine-induced responses

(2014) E Cahill et al.   MOLECULAR PSYCHIATRY

L-DOPA Treatment Selectively Restores Spine Density in Dopamine Receptor D2–Expressing Projection Neurons in Dyskinetic Mice

(2013) Luz M. Suárez et al.   BIOLOGICAL PSYCHIATRY

Synaptic adhesion molecules in Cadm family at the neuromuscular junction

(2013) Yuko Tanabe et al.   CELL BIOLOGY INTERNATIONAL

Protective effects of EphB2 on Aβ1–42 oligomer-induced neurotoxicity and synaptic NMDA receptor signaling in hippocampal neurons

(2013) Dandan Geng et al.   NEUROCHEMISTRY INTERNATIONAL

Impaired autophagy, chaperone expression, and protein synthesis in response to critical illness interventions in porcine skeletal muscle

(2013) Varuna C. Banduseela et al.   PHYSIOLOGICAL GENOMICS

Combinatorial topography and cell-type specific regulation of the ERK pathway by dopaminergic agonists in the mouse striatum

(2012) Giuseppe Gangarossa et al.   Brain Structure & Function

Fibroblast growth factor 2 regulates adequate nigrostriatal pathway formation in mice

(2012) Olga Baron et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Unique gene alterations are induced in FACS-purified Fos-positive neurons activated during cue-induced relapse to heroin seeking

(2012) Sanya Fanous et al.   JOURNAL OF NEUROCHEMISTRY

L-DOPA-induced increase in TH-immunoreactive striatal neurons in parkinsonian mice: Insights into regulation and function

(2012) Isabel Espadas et al.   NEUROBIOLOGY OF DISEASE

Comparison of rating scales used to evaluate l-DOPA-induced dyskinesia in the 6-OHDA lesioned rat

(2012) Ludivine S. Breger et al.   NEUROBIOLOGY OF DISEASE

Hypoxia and neural stem cells: from invertebrates to brain cancer stem cells

(2011) Ferdinando Mannello et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Cocaine induces the expression of MEF2C transcription factor in rat striatum through activation of SIK1 and phosphorylation of the histone deacetylase HDAC5

(2011) Jean-Bernard Dietrich et al.   SYNAPSE

L-DOPA-Induced Dyskinesia and Abnormal Signaling in Striatal Medium Spiny Neurons: Focus on Dopamine D1 Receptor-Mediated Transmission

(2011) Michael Feyder et al.   Frontiers in Behavioral Neuroscience

Striatal Overexpression of  FosB Reproduces Chronic Levodopa-Induced Involuntary Movements

(2010) X. Cao et al.   JOURNAL OF NEUROSCIENCE

Striatal inhibition of PKA prevents levodopa-induced behavioural and molecular changes in the hemiparkinsonian rat

(2010) Manon Lebel et al.   NEUROBIOLOGY OF DISEASE

Genetic Inactivation of Dopamine D1 but Not D2 Receptors Inhibits L-DOPA–Induced Dyskinesia and Histone Activation

(2009) Sanja Darmopil et al.   BIOLOGICAL PSYCHIATRY

Translational Control of Long-Lasting Synaptic Plasticity and Memory

(2009) Mauro Costa-Mattioli et al.   NEURON

A new ethyladenine antagonist of adenosine A2A receptors: Behavioral and biochemical characterization as an antiparkinsonian drug

(2009) Annalisa Pinna et al.   NEUROPHARMACOLOGY

Differential Involvement of D1 and D2 Dopamine Receptors in L-DOPA-Induced Angiogenic Activity in a Rat Model of Parkinson's Disease

(2009) Hanna S Lindgren et al.   NEUROPSYCHOPHARMACOLOGY

Inhibition of mTOR Signaling in Parkinson's Disease Prevents L-DOPA-Induced Dyskinesia

(2009) E. Santini et al.   Science Signaling

Oncogenic MAPK Signaling Stimulates mTORC1 Activity by Promoting RSK-Mediated Raptor Phosphorylation

(2008) Audrey Carrière et al.   CURRENT BIOLOGY

Tyrosine hydroxylase cells appearing in the mouse striatum after dopamine denervation are likely to be projection neurones regulated by l-DOPA

(2008) Sanja Darmopil et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

l-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice

(2008) Emanuela Santini et al.   JOURNAL OF NEUROCHEMISTRY

A Potential Neuroanatomical Dissociation of DARPP-32 in Striatal ERK Signaling

(2008) K. B. Dupre   JOURNAL OF NEUROSCIENCE

Differences between Dorsal and Ventral Striatum in Drd1a Dopamine Receptor Coupling of Dopamine- and cAMP-Regulated Phosphoprotein-32 to Activation of Extracellular Signal-Regulated Kinase

(2008) C. R. Gerfen et al.   JOURNAL OF NEUROSCIENCE

Phosphorylation of ΔFosB mediates its stability in vivo

(2008) P.G. Ulery-Reynolds et al.   NEUROSCIENCE

Transcriptional mechanisms of addiction: role of  FosB

(2008) E. J Nestler   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A Nurr1 point mutant, implicated in Parkinson’s disease, uncouples ERK1/2-dependent regulation of tyrosine hydroxylase transcription

(2007) Kirsten X. Jacobsen et al.   NEUROBIOLOGY OF DISEASE