Attenuation of the Infiltration of Angiotensin II Expressing CD3+ T-Cells and the Modulation of Nerve Growth Factor in Lumbar Dorsal Root Ganglia – A Possible Mechanism Underpinning Analgesia Produced by EMA300, An Angiotensin II Type 2 (AT2) Receptor Antagonist
出版年份 2017 全文链接
标题
Attenuation of the Infiltration of Angiotensin II Expressing CD3+ T-Cells and the Modulation of Nerve Growth Factor in Lumbar Dorsal Root Ganglia – A Possible Mechanism Underpinning Analgesia Produced by EMA300, An Angiotensin II Type 2 (AT2) Receptor Antagonist
作者
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出版物
Frontiers in Molecular Neuroscience
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2017-11-21
DOI
10.3389/fnmol.2017.00389
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Nociceptor-like rat dorsal root ganglion neurons express the angiotensin-II AT2 receptor throughout development
- (2017) Sergio Benitez et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Spinal translocator protein alleviates chronic neuropathic pain behavior and modulates spinal astrocyte–neuronal function in rats with L5 spinal nerve ligation model
- (2016) Xiaoming Liu et al. PAIN
- Selective small molecule angiotensin II type 2 receptor antagonists for neuropathic pain
- (2016) Maree T. Smith et al. PAIN
- Drug Repurposing for the Development of Novel Analgesics
- (2016) Marco Sisignano et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Developmental Changes in Pain and Spinal Immune Gene Expression after Radicular Trauma in the Rat
- (2016) Gordon A. Barr et al. Frontiers in Neurology
- The mature/pro nerve growth factor ratio is decreased in the brain of diabetic rats: Analysis by ELISA methods
- (2015) Marzia Soligo et al. BRAIN RESEARCH
- Evidence for a distinct neuro-immune signature in rats that develop behavioural disability after nerve injury
- (2015) Paul J Austin et al. Journal of Neuroinflammation
- Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis
- (2015) Nanna B Finnerup et al. LANCET NEUROLOGY
- A Pro-Nerve Growth Factor (proNGF) and NGF Binding Protein, α2-Macroglobulin, Differentially Regulates p75 and TrkA Receptors and Is Relevant to NeurodegenerationEx VivoandIn Vivo
- (2015) Pablo F. Barcelona et al. MOLECULAR AND CELLULAR BIOLOGY
- Mechanisms Underlying Clinical Efficacy of Angiotensin II Type 2 Receptor (AT2R) Antagonist EMA401 in Neuropathic Pain: Clinical Tissue and in Vitro Studies
- (2015) Uma Anand et al. Molecular Pain
- Neurotrophins and Neuropathic Pain: Role in Pathobiology
- (2015) Nemat Khan et al. MOLECULES
- Angiotensin II Type 2-Receptor: New Clinically Validated Target in the Treatment of Neuropathic Pain
- (2015) ASC Rice et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Analgesic efficacy of small-molecule angiotensin II type 2 receptor antagonists in a rat model of antiretroviral toxic polyneuropathy
- (2014) Maree T. Smith et al. BEHAVIOURAL PHARMACOLOGY
- AT2 Receptor and Tissue Injury: Therapeutic Implications
- (2014) Pawel Namsolleck et al. CURRENT HYPERTENSION REPORTS
- EMA401, an orally administered highly selective angiotensin II type 2 receptor antagonist, as a novel treatment for postherpetic neuralgia: a randomised, double-blind, placebo-controlled phase 2 clinical trial
- (2014) Andrew S C Rice et al. LANCET
- Angiotensin II: from blood pressure to pain control
- (2014) Nanna Brix Finnerup et al. LANCET
- Effect of Subpressor Dose of Angiotensin II on Pain-Related Behavior in Relation with Neuronal Injury and Activation of Satellite Glial Cells in the Rat Dorsal Root Ganglia
- (2013) Jaroslav Pavel et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Local and Remote Immune-Mediated Inflammation After Mild Peripheral Nerve Compression in Rats
- (2013) Annina B. Schmid et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Finding the right antibody for the job
- (2013) Vivien Marx NATURE METHODS
- Small Molecule Angiotensin II Type 2 Receptor (AT2R) Antagonists as Novel Analgesics for Neuropathic Pain: Comparative Pharmacokinetics, Radioligand Binding, and Efficacy in Rats
- (2013) Maree T. Smith et al. PAIN MEDICINE
- A Small Molecule Angiotensin II Type 2 Receptor (AT2R) Antagonist Produces Analgesia in a Rat Model of Neuropathic Pain by Inhibition of p38 Mitogen-Activated Protein Kinase (MAPK) and p44/p42 MAPK Activation in the Dorsal Root Ganglia
- (2013) Maree T. Smith et al. PAIN MEDICINE
- Analgesic Efficacy and Mode of Action of a Selective Small Molecule Angiotensin II Type 2 Receptor Antagonist in a Rat Model of Prostate Cancer-Induced Bone Pain
- (2013) Arjun Muralidharan et al. PAIN MEDICINE
- Commercially Available Angiotensin II At2 Receptor Antibodies Are Nonspecific
- (2013) Roman Hafko et al. PLoS One
- Clinical pharmacology of analgesics assessed with human experimental pain models: bridging basic and clinical research
- (2012) Bruno Georg Oertel et al. BRITISH JOURNAL OF PHARMACOLOGY
- Angiotensin II type 2 receptor (AT2R) localization and antagonist-mediated inhibition of capsaicin responses and neurite outgrowth in human and rat sensory neurons
- (2012) U. Anand et al. EUROPEAN JOURNAL OF PAIN
- Neurotrophic Factor Changes in the Rat Thick Skin following Chronic Constriction Injury of the Sciatic Nerve
- (2012) Jennifer C Peleshok et al. Molecular Pain
- Regulatory T cells attenuate neuropathic pain following peripheral nerve injury and experimental autoimmune neuritis
- (2012) Paul J. Austin et al. PAIN
- How does angiotensin AT2 receptor activation help neuronal differentiation and improve neuronal pathological situations?
- (2012) Marie-Odile Guimond et al. Frontiers in Endocrinology
- The Angiotensin II Type 2 Receptor in Brain Functions: An Update
- (2012) Marie-Odile Guimond et al. International Journal of Hypertension
- ETA Activation Mediates Angiotensin II-Induced Infiltration of Renal Cortical T Cells
- (2011) E. I. Boesen et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- ERK1/2 Mitogen-Activated Protein Kinase Phosphorylates Sodium Channel Nav1.7 and Alters Its Gating Properties
- (2010) S. Stamboulian et al. JOURNAL OF NEUROSCIENCE
- Overcoming obstacles to developing new analgesics
- (2010) Clifford J Woolf NATURE MEDICINE
- The angiotensin II type 2 (AT2) receptor: an enigmatic seven transmembrane receptor
- (2009) Enzo et al. Frontiers in Bioscience-Landmark
- T-Cell Infiltration and Signaling in the Adult Dorsal Spinal Cord Is a Major Contributor to Neuropathic Pain-Like Hypersensitivity
- (2009) M. Costigan et al. JOURNAL OF NEUROSCIENCE
- Regulation of T-cell function by endogenously produced angiotensin II
- (2008) Nyssa E. Hoch et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Phosphorylation of Sodium Channel Nav1.8 by p38 Mitogen-Activated Protein Kinase Increases Current Density in Dorsal Root Ganglion Neurons
- (2008) A. Hudmon et al. JOURNAL OF NEUROSCIENCE
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