AIM2 Co-immunization with VP1 Is Associated with Increased Memory CD8 T Cells and Mounts Long Lasting Protection against Coxsackievirus B3 Challenge

Vesicular Stomatitis Virus-Vectored Multi-Antigen Tuberculosis Vaccine Limits Bacterial Proliferation in Mice following a Single Intranasal Dose

(2017) Ming Zhang et al.   Frontiers in Cellular and Infection Microbiology

Dual roles of calpain in facilitating Coxsackievirus B3 replication and prompting inflammation in acute myocarditis

(2016) Minghui Li et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

AIM2 co-immunization favors specific multifunctional CD8+ T cell induction and ameliorates coxsackievirus B3-induced chronic myocarditis

(2015) Dafei Chai et al.   ANTIVIRAL RESEARCH

Novel vaccine approaches for protection against intracellular pathogens

(2014) Kristin L Griffiths et al.   CURRENT OPINION IN IMMUNOLOGY

Identification of Aim2 as a Sensor for DNA Vaccines

(2014) John J. Suschak et al.   JOURNAL OF IMMUNOLOGY

Mucosal co-immunization with AIM2 enhances protective SIgA response and increases prophylactic efficacy of chitosan-DNA vaccine against coxsackievirus B3-induced myocarditis

(2014) Dafei Chai et al.   Human Vaccines & Immunotherapeutics

IL-27 enhances the survival of tumor antigen-specific CD8+T cells and programs them into IL-10-producing, memory precursor-like effector cells

(2012) Zhenzhen Liu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Current treatment options in (peri)myocarditis and inflammatory cardiomyopathy

(2012) B. Maisch et al.   HERZ

Intratumoral Delivery of Low Doses of Anti-CD40 mAb Combined With Monophosphoryl Lipid A Induces Local and Systemic Antitumor Effects in Immunocompetent and T Cell-Deficient Mice

(2012) Tyler J. Van De Voort et al.   JOURNAL OF IMMUNOTHERAPY

IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques

(2012) Rashmi Jalah et al.   Human Vaccines & Immunotherapeutics

Astragaloside IV attenuates myocardial fibrosis by inhibiting TGF-β1 signaling in coxsackievirus B3-induced cardiomyopathy

(2011) Ping Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Heterologous Plasmid DNA Prime-Recombinant Human Adenovirus 5 Boost Vaccination Generates a Stable Pool of Protective Long-Lived CD8+T Effector Memory Cells Specific for a Human Parasite, Trypanosoma cruzi

(2011) Paula Ordonhez Rigato et al.   INFECTION AND IMMUNITY

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

(2011) Scott G. Hansen et al.   NATURE

Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells

(2011) M. K. L. MacLeod et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD4+ T Cells Are Not Required for the Induction of Dengue Virus-Specific CD8+ T Cell or Antibody Responses but Contribute to Protection after Vaccination

(2010) L. E. Yauch et al.   JOURNAL OF IMMUNOLOGY

Coadministration of Interleukins 7 and 15 with Bacille Calmette‐Guérin Mounts Enduring T Cell Memory Response againstMycobacterium tuberculosis

(2010) Vijender Singh et al.   JOURNAL OF INFECTIOUS DISEASES

Interferon-Inducible p200-Family Proteins as Novel Sensors of Cytoplasmic DNA: Role in Inflammation and Autoimmunity

(2010) Divaker Choubey et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

DAI (DLM-1/ZBP1) as a Genetic Adjuvant for DNA Vaccines That Promotes Effective Antitumor CTL Immunity

(2010) Alvaro Lladser et al.   MOLECULAR THERAPY

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

(2010) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

(2010) Teresa Fernandes-Alnemri et al.   NATURE IMMUNOLOGY

Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis

(2010) J. W. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

Pathogen recognition in the innate immune response

(2009) Himanshu Kumar et al.   BIOCHEMICAL JOURNAL

Innate Immunity: Cytoplasmic DNA Sensing by the AIM2 Inflammasome

(2009) Kate Schroder et al.   CURRENT BIOLOGY

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA

(2009) T. L. Roberts et al.   SCIENCE

Enumeration and Functional Evaluation of Virus-Specific CD4+ and CD8+ T Cells in Lymphoid and Peripheral Sites of Coxsackievirus B3 Infection

(2008) C. C. Kemball et al.   JOURNAL OF VIROLOGY