Host cell interactions of outer membrane vesicle-associated virulence factors of enterohemorrhagic Escherichia coli O157: Intracellular delivery, trafficking and mechanisms of cell injury

Bacterial genotoxins: The long journey to the nucleus of mammalian cells

(2016) Teresa Frisan   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria

(2016) Sandro Roier et al.   Nature Communications

Outer Membrane Vesicles from the Probiotic Escherichia coli Nissle 1917 and the Commensal ECOR12 Enter Intestinal Epithelial Cells via Clathrin-Dependent Endocytosis and Elicit Differential Effects on DNA Damage

(2016) María-Alexandra Cañas et al.   PLoS One

Cytolethal distending toxin A, B and C subunit proteins are necessary for the genotoxic effect ofEscherichia coliCDT-V

(2015) Frederic Taieb et al.   ACTA VETERINARIA HUNGARICA

Virulence from vesicles: Novel mechanisms of host cell injury by Escherichia coli O104:H4 outbreak strain

(2015) Lisa Kunsmann et al.   Scientific Reports

A Novel Mechanism of Bacterial Toxin Transfer within Host Blood Cell-Derived Microvesicles

(2015) Anne-lie Ståhl et al.   PLoS Pathogens

Distinct Roles for CdtA and CdtC during Intoxication by Cytolethal Distending Toxins

(2015) Shandee D. Dixon et al.   PLoS One

Aggregatibacter actinomycetemcomitans Outer Membrane Vesicles Are Internalized in Human Host Cells and Trigger NOD1- and NOD2-Dependent NF-κB Activation

(2014) Bernard Thay et al.   INFECTION AND IMMUNITY

Cytolethal Distending Toxins Require Components of the ER-Associated Degradation Pathway for Host Cell Entry

(2014) Aria Eshraghi et al.   PLoS Pathogens

Uptake and Processing of the Cytolethal Distending Toxin by Mammalian Cells

(2014) Joseph DiRienzo   Toxins

The Cytolethal Distending Toxin Effects on Mammalian Cells: A DNA Damage Perspective

(2014) Elisabeth Bezine et al.   Cells

Salmonella entericadelivers its genotoxin through outer membrane vesicles secreted from infected cells

(2013) Riccardo Guidi et al.   CELLULAR MICROBIOLOGY

Retrograde transport of protein toxins through the Golgi apparatus

(2013) Kirsten Sandvig et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Cellular Interactions of the Cytolethal Distending Toxins fromEscherichia coliandHaemophilus ducreyi

(2013) Amandeep Gargi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Polyclonal Antibody Based Immunoassay Detects Seven Subtypes of Shiga Toxin 2 Produced by Escherichia coli in Human and Environmental Samples

(2013) Xiaohua He et al.   PLoS One

Enterohemorrhagic Escherichia coli Hemolysin Employs Outer Membrane Vesicles to Target Mitochondria and Cause Endothelial and Epithelial Apoptosis

(2013) Martina Bielaszewska et al.   PLoS Pathogens

Localization of Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Subunits during Intoxication of Live Cells

(2012) Monika Damek-Poprawa et al.   INFECTION AND IMMUNITY

BioImageXD: an open, general-purpose and high-throughput image-processing platform

(2012) Pasi Kankaanpää et al.   NATURE METHODS

Enterohemorrhagic Escherichia coli Specific Enterohemolysin Induced IL-1β in Human Macrophages and EHEC-Induced IL-1β Required Activation of NLRP3 Inflammasome

(2012) Xiaoai Zhang et al.   PLoS One

Shiga toxins

(2012) Jonas Bergan et al.   TOXICON

Bacterial toxin modulation of the eukaryotic cell cycle: are all cytolethal distending toxins created equally?

(2012) Amandeep Gargi et al.   Frontiers in Cellular and Infection Microbiology

Mouse model for hemolytic uremic syndrome induced by outer membrane vesicles ofEscherichia coliO157:H7

(2011) Sang-Hyun Kim et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Perinuclear Localization of Internalized Outer Membrane Vesicles Carrying Active Cytolethal Distending Toxin from Aggregatibacter actinomycetemcomitans

(2011) Pramod Kumar Rompikuntal et al.   INFECTION AND IMMUNITY

Shiga toxin glycosphingolipid receptors in microvascular and macrovascular endothelial cells: differential association with membrane lipid raft microdomains

(2011) Josefine Betz et al.   JOURNAL OF LIPID RESEARCH

Cytolethal distending toxin: a conserved bacterial genotoxin that blocks cell cycle progression, leading to apoptosis of a broad range of mammalian cell lineages

(2011) R. N. Jinadasa et al.   MICROBIOLOGY-SGM

Tumor-Specific Targeting of Pancreatic Cancer with Shiga Toxin B-Subunit

(2011) M. Maak et al.   MOLECULAR CANCER THERAPEUTICS

The Biology of the Cytolethal Distending Toxins

(2011) Lina Guerra et al.   Toxins

Helicobacter hepaticusCytolethal Distending Toxin Causes Cell Death in Intestinal Epithelial Cells via Mitochondrial Apoptotic Pathway

(2010) Namal P. M. Liyanage et al.   HELICOBACTER

EspP, a Serine Protease of Enterohemorrhagic Escherichia coli, Impairs Complement Activation by Cleaving Complement Factors C3/C3b and C5

(2010) D. Orth et al.   INFECTION AND IMMUNITY

Shiga Toxin 2 and Flagellin from Shiga-Toxigenic Escherichia coli Superinduce Interleukin-8 through Synergistic Effects on Host Stress-Activated Protein Kinase Activation

(2010) D. M. Jandhyala et al.   INFECTION AND IMMUNITY

Virulence and Immunomodulatory Roles of Bacterial Outer Membrane Vesicles

(2010) T. N. Ellis et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Shiga toxin-associated hemolytic uremic syndrome: pathophysiology of endothelial dysfunction

(2010) Carla Zoja et al.   PEDIATRIC NEPHROLOGY

Differential cytotoxic actions of Shiga toxin 1 and Shiga toxin 2 on microvascular and macrovascular endothelial cells

(2010) Andreas Bauwens et al.   THROMBOSIS AND HAEMOSTASIS

Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells

(2009) Maria Kaparakis et al.   CELLULAR MICROBIOLOGY

Globotriaosyl ceramide receptor function - Where membrane structure and pathology intersect

(2009) C.A. Lingwood et al.   FEBS LETTERS

Long-Distance Delivery of Bacterial Virulence Factors by Pseudomonas aeruginosa Outer Membrane Vesicles

(2009) Jennifer M. Bomberger et al.   PLoS Pathogens