The Biology of the Cytolethal Distending Toxins

Bacterial genotoxin triggers FEN1-dependent RhoA activation, cytoskeleton remodeling and cell survival

(2011) L. Guerra et al.   JOURNAL OF CELL SCIENCE

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Cytolethal Distending Toxin Family Members Are Differentially Affected by Alterations in Host Glycans and Membrane Cholesterol

(2010) Aria Eshraghi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aggregatibacter (Actinobacillus) actinomycetemcomitans: a triple A* periodontopathogen?

(2010) Brian Henderson et al.   PERIODONTOLOGY 2000

Myc Is Required for Activation of the ATM-Dependent Checkpoints in Response to DNA Damage

(2010) Lina Guerra et al.   PLoS One

Outer membrane vesicle-mediated release of cytolethal distending toxin (CDT) from Campylobacter jejuni

(2009) Barbro Lindmark et al.   BMC MICROBIOLOGY

Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Induces Apoptosis in Nonproliferating Macrophages by a Phosphatase-Independent Mechanism

(2009) S. D. P. Rabin et al.   INFECTION AND IMMUNITY

Cytolethal Distending Toxin from Aggregatibacter actinomycetemcomitans Induces DNA Damage, S/G2 Cell Cycle Arrest, and Caspase- Independent Death in a Saccharomyces cerevisiae Model

(2009) O. Matangkasombut et al.   INFECTION AND IMMUNITY

Bacterial intoxication evokes cellular senescence with persistent DNA damage and cytokine signalling

(2009) Hana Blazkova et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Haploid Genetic Screens in Human Cells Identify Host Factors Used by Pathogens

(2009) J. E. Carette et al.   SCIENCE

Cytolethal distending toxin upregulates RANKL expression in Jurkat T-cells

(2008) GEORGIOS N. BELIBASAKIS et al.   APMIS

A novel mode of translocation for cytolethal distending toxin

(2008) Lina Guerra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Delivery of a Salmonella Typhi Exotoxin from a Host Intracellular Compartment

(2008) Stefania Spanò et al.   Cell Host & Microbe

Cytolethal Distending Toxin Induces Caspase-Dependent and -Independent Cell Death in MOLT-4 Cells

(2008) M. Ohara et al.   INFECTION AND IMMUNITY

A Bacterial Cytotoxin Identifies the RhoA Exchange Factor Net1 as a Key Effector in the Response to DNA Damage

(2008) Lina Guerra et al.   PLoS One

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE