Analysis of large versus small dogs reveals three genes on the canine X chromosome associated with body weight, muscling and back fat thickness

Whole-genome sequence, SNP chips and pedigree structure: building demographic profiles in domestic dog breeds to optimize genetic-trait mapping

(2016) Dayna L. Dreger et al.   Disease Models & Mechanisms

IGSF1 Deficiency: Lessons From an Extensive Case Series and Recommendations for Clinical Management

(2016) S. D. Joustra et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genomic and archaeological evidence suggest a dual origin of domestic dogs

(2016) Laurent A. F. Frantz et al.   SCIENCE

Complex disease and phenotype mapping in the domestic dog

(2016) Jessica J. Hayward et al.   Nature Communications

The Ensembl gene annotation system

(2016) Bronwen L. Aken et al.   Database-The Journal of Biological Databases and Curation

Demographically-Based Evaluation of Genomic Regions under Selection in Domestic Dogs

(2016) Adam H. Freedman et al.   PLoS Genetics

Systematic Analysis of Gene Expression Alterations and Clinical Outcomes for Long-Chain Acyl-Coenzyme A Synthetase Family in Cancer

(2016) Wei-Ching Chen et al.   PLoS One

Linked genetic variants on chromosome 10 control ear morphology and body mass among dog breeds

(2015) Matthew Webster et al.   BMC GENOMICS

Ancient Wolf Genome Reveals an Early Divergence of Domestic Dog Ancestors and Admixture into High-Latitude Breeds

(2015) Pontus Skoglund et al.   CURRENT BIOLOGY

Combined Growth Hormone and Thyroid-Stimulating Hormone Deficiency in a Japanese Patient with a Novel Frameshift Mutation in IGSF1

(2015) Yumi Asakura et al.   Hormone Research in Paediatrics

A Spontaneous KRT16 Mutation in a Dog Breed: A Model for Human Focal Non-Epidermolytic Palmoplantar Keratoderma (FNEPPK)

(2015) Jocelyn Plassais et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Homologous Mutation to Human BRAF V600E Is Common in Naturally Occurring Canine Bladder Cancer--Evidence for a Relevant Model System and Urine-Based Diagnostic Test

(2015) B. Decker et al.   MOLECULAR CANCER RESEARCH

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

Insights into Morphology and Disease from the Dog Genome Project

(2014) Jeffrey J. Schoenebeck et al.   Annual Review of Cell and Developmental Biology

IGSF1 variants in boys with familial delayed puberty

(2014) Sjoerd D. Joustra et al.   EUROPEAN JOURNAL OF PEDIATRICS

The role of hypothalamic estrogen receptors in metabolic regulation

(2014) Aaron Frank et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Efficient multivariate linear mixed model algorithms for genome-wide association studies

(2014) Xiang Zhou et al.   NATURE METHODS

Unique transcriptomic signature of omental adipose tissue in Ossabaw swine: a model of childhood obesity

(2014) Ryan G. Toedebusch et al.   PHYSIOLOGICAL GENOMICS

Expression of Long-chain Fatty Acyl-CoA Synthetase 4 in Breast and Prostate Cancers Is Associated with Sex Steroid Hormone Receptor Negativity

(2014) Marie E. Monaco et al.   Translational Oncology

Genome Sequencing Highlights the Dynamic Early History of Dogs

(2014) Adam H. Freedman et al.   PLoS Genetics

A Mutation in the FAM83G Gene in Dogs with Hereditary Footpad Hyperkeratosis (HFH)

(2014) Michaela Drögemüller et al.   PLoS Genetics

Fine mapping of fatness QTL on porcine chromosome X and analyses of three positional candidate genes

(2013) Junwu Ma et al.   BMC GENETICS

Three NovelIGSF1Mutations in Four Japanese Patients With X-Linked Congenital Central Hypothyroidism

(2013) Akie Nakamura et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The genomic signature of dog domestication reveals adaptation to a starch-rich diet

(2013) Erik Axelsson et al.   NATURE

Long Chain Fatty Acyl-CoA Synthetase 4 Is a Biomarker for and Mediator of Hormone Resistance in Human Breast Cancer

(2013) Xinyu Wu et al.   PLoS One

Complete Mitochondrial Genomes of Ancient Canids Suggest a European Origin of Domestic Dogs

(2013) O. Thalmann et al.   SCIENCE

A Copy Number Variant at the KITLG Locus Likely Confers Risk for Canine Squamous Cell Carcinoma of the Digit

(2013) Danielle M. Karyadi et al.   PLoS Genetics

Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B

(2013) Elinor K Karlsson et al.   GENOME BIOLOGY

Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis

(2013) Marianna Sadagurski et al.   Molecular Metabolism

Evaluation of the porcineACSL4gene as a candidate gene for meat quality traits in pigs

(2012) J. Corominas et al.   ANIMAL GENETICS

The MTAP-CDKN2A Locus Confers Susceptibility to a Naturally Occurring Canine Cancer

(2012) A. L. Shearin et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Modular Genetic Control of Sexually Dimorphic Behaviors

(2012) Xiaohong Xu et al.   CELL

The insulin-like growth factor 1 receptor (IGF1R) contributes to reduced size in dogs

(2012) Barbara C. Hoopes et al.   MAMMALIAN GENOME

Loss-of-function mutations in IGSF1 cause an X-linked syndrome of central hypothyroidism and testicular enlargement

(2012) Yu Sun et al.   NATURE GENETICS

PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans

(2012) Anaïs Grall et al.   NATURE GENETICS

Genome-wide efficient mixed-model analysis for association studies

(2012) Xiang Zhou et al.   NATURE GENETICS

A SINE-Derived Element Constitutes a Unique Modular Enhancer for Mammalian Diencephalic Fgf8

(2012) Akiko Nakanishi et al.   PLoS One

Rethinking dog domestication by integrating genetics, archeology, and biogeography

(2012) G. Larson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Variation of BMP3 Contributes to Dog Breed Skull Diversity

(2012) Jeffrey J. Schoenebeck et al.   PLoS Genetics

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

A 33,000-Year-Old Incipient Dog from the Altai Mountains of Siberia: Evidence of the Earliest Domestication Disrupted by the Last Glacial Maximum

(2011) Nikolai D. Ovodov et al.   PLoS One

A Mammalian Conserved Element Derived from SINE Displays Enhancer Properties Recapitulating Satb2 Expression in Early-Born Callosal Projection Neurons

(2011) Kensuke Tashiro et al.   PLoS One

Identification of Genomic Regions Associated with Phenotypic Variation between Dog Breeds using Selection Mapping

(2011) Amaury Vaysse et al.   PLoS Genetics

The domestic dog: man's best friend in the genomic era

(2011) Adam R Boyko   GENOME BIOLOGY

Man's Best Friend Becomes Biology's Best in Show: Genome Analyses in the Domestic Dog

(2010) Heidi G. Parker et al.   Annual Review of Genetics

Porcine insulin receptor substrate 4 (IRS4) gene: cloning, polymorphism and association study

(2010) Martin Masopust et al.   MOLECULAR BIOLOGY REPORTS

CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs

(2010) Anne-Christine Merveille et al.   NATURE GENETICS

mtDNA Data Indicate a Single Origin for Dogs South of Yangtze River, Less Than 16,300 Years Ago, from Numerous Wolves

(2009) J.-F. Pang et al.   MOLECULAR BIOLOGY AND EVOLUTION

Mammalian Long-Chain Acyl-CoA Synthetases

(2008) Eric Soupene et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Fossil dogs and wolves from Palaeolithic sites in Belgium, the Ukraine and Russia: osteometry, ancient DNA and stable isotopes

(2008) Mietje Germonpré et al.   JOURNAL OF ARCHAEOLOGICAL SCIENCE

Growth Hormone (GH) Insensitivity and Insulin-Like Growth Factor-I Deficiency in Inuit Subjects and an Ecuadorian Cohort: Functional Studies of Two Codon 180 GH Receptor Gene Mutations

(2007) Peng Fang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM