Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B

The genomic signature of dog domestication reveals adaptation to a starch-rich diet

(2013) Erik Axelsson et al.   NATURE

Genome-wide association study identifies two susceptibility loci for osteosarcoma

(2013) Sharon A Savage et al.   NATURE GENETICS

FAM5C is a soluble osteoblast differentiation factor linking muscle to bone

(2012) Ken-ichiro Tanaka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

INRICH: interval-based enrichment analysis for genome-wide association studies

(2012) Phil H. Lee et al.   BIOINFORMATICS

The MTAP-CDKN2A Locus Confers Susceptibility to a Naturally Occurring Canine Cancer

(2012) A. L. Shearin et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

miRNA Signatures Associate with Pathogenesis and Progression of Osteosarcoma

(2012) K. B. Jones et al.   CANCER RESEARCH

Ezh1 Is Required for Hematopoietic Stem Cell Maintenance and Prevents Senescence-like Cell Cycle Arrest

(2012) Isabel Hidalgo et al.   Cell Stem Cell

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data

(2012) Marieke L. Kuijjer et al.   GENES CHROMOSOMES & CANCER

P16 expression predicts necrotic response among patients with osteosarcoma receiving neoadjuvant chemotherapy

(2012) Dariusz Borys et al.   HUMAN PATHOLOGY

The transcription factor paired box-5 promotes osteoblastogenesis through direct induction ofOsterixandOsteocalcin

(2012) Eiichi Hinoi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Genome-wide association study of obsessive-compulsive disorder

(2012) S E Stewart et al.   MOLECULAR PSYCHIATRY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

The accessible chromatin landscape of the human genome

(2012) Robert E. Thurman et al.   NATURE

The UCSC Genome Browser database: extensions and updates 2013

(2012) Laurence R. Meyer et al.   NUCLEIC ACIDS RESEARCH

A genome-wide approach to comparative oncology: high-resolution oligonucleotide aCGH of canine and human osteosarcoma pinpoints shared microaberrations

(2012) Andrea Y. Angstadt et al.   Cancer Genetics

Attention-Deficit/Hyperactivity Disorder Genomics: Update for Clinicians

(2012) Josephine Elia et al.   Current Psychiatry Reports

Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder

(2012) P H Lee et al.   Translational Psychiatry

FIMO: scanning for occurrences of a given motif

(2011) Charles E. Grant et al.   BIOINFORMATICS

Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach

(2011) Milcah C. Scott et al.   BONE

Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma

(2011) Venugopal Thayanithy et al.   BONE

Identification of the bleomycin hydrolase gene as a methylated tumor suppressor gene in hepatocellular carcinoma using a novel triple-combination array method

(2011) Yukiyasu Okamura et al.   CANCER LETTERS

IκBζ expression is regulated by miR-124a

(2011) Charlotte Lindenblatt et al.   CELL CYCLE

NELL-1 binds to APR3 affecting human osteoblast proliferation and differentiation

(2011) Xuan Zou et al.   FEBS LETTERS

OTX2 directly activates cell cycle genes and inhibits differentiation in medulloblastoma cells

(2011) Jens Bunt et al.   INTERNATIONAL JOURNAL OF CANCER

Refining tumor-associated aneuploidy through ‘genomic recoding’ of recurrent DNA copy number aberrations in 150 canine non-Hodgkin lymphomas

(2011) Rachael Thomas et al.   LEUKEMIA & LYMPHOMA

A high-resolution map of human evolutionary constraint using 29 mammals

(2011) Kerstin Lindblad-Toh et al.   NATURE

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

(2011) Olivier Harismendy et al.   NATURE

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

ENCODE whole-genome data in the UCSC Genome Browser: update 2012

(2011) K. R. Rosenbloom et al.   NUCLEIC ACIDS RESEARCH

NCBI Reference Sequences (RefSeq): current status, new features and genome annotation policy

(2011) K. D. Pruitt et al.   NUCLEIC ACIDS RESEARCH

Analysis of miRNA-gene expression-genomic profiles reveals complex mechanisms of microRNA deregulation in osteosarcoma

(2011) Georges Maire et al.   Cancer Genetics

Identification of Genomic Regions Associated with Phenotypic Variation between Dog Breeds using Selection Mapping

(2011) Amaury Vaysse et al.   PLoS Genetics

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

How B cells influence bone biology in health and disease

(2010) Mark C. Horowitz et al.   BONE

Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer

(2010) Martin Sauvageau et al.   Cell Stem Cell

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

S-MED: Sarcoma microRNA Expression Database

(2010) Aaron L Sarver et al.   LABORATORY INVESTIGATION

Genome-wide association mapping identifies multiple loci for a canine SLE-related disease complex

(2010) Maria Wilbe et al.   NATURE GENETICS

Variance component model to account for sample structure in genome-wide association studies

(2010) Hyun Min Kang et al.   NATURE GENETICS

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++

(2010) Eugene V. Davydov et al.   PLoS Computational Biology

A Unified Approach to Genotype Imputation and Haplotype-Phase Inference for Large Data Sets of Trios and Unrelated Individuals

(2009) Brian L. Browning et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression

(2009) Melissa Paoloni et al.   BMC GENOMICS

Osteosarcoma treatment: state of the art

(2009) Hang T. Ta et al.   CANCER AND METASTASIS REVIEWS

Epigenetic Silencing of the Tumor Suppressor MicroRNA Hsa-miR-124a Regulates CDK6 Expression and Confers a Poor Prognosis in Acute Lymphoblastic Leukemia

(2009) X. Agirre et al.   CANCER RESEARCH

A canine chromosome 7 locus confers compulsive disorder susceptibility

(2009) N H Dodman et al.   MOLECULAR PSYCHIATRY

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions

(2009) Soumya Raychaudhuri et al.   PLoS Genetics

Osteosarcoma Development and Stem Cell Differentiation

(2008) Ni Tang et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

(2008) C. R. Walkley et al.   GENES & DEVELOPMENT

PID: the Pathway Interaction Database

(2008) Carl F. Schaefer et al.   NUCLEIC ACIDS RESEARCH

Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage

(2008) S. D. Berman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA