Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain

Early Changes in Hippocampal Eph Receptors Precede the Onset of Memory Decline in Mouse Models of Alzheimer's Disease

(2017) Ana María Simón et al.   JOURNAL OF ALZHEIMERS DISEASE

Ephrin-B2 prevents N-methyl-D-aspartate receptor antibody effects on memory and neuroplasticity

(2016) Jesús Planagumà et al.   ANNALS OF NEUROLOGY

A Single Kinase Generates the Majority of the Secreted Phosphoproteome

(2015) Vincent S. Tagliabracci et al.   CELL

Anchoring and synaptic stability of PSD-95 is driven by ephrin-B3

(2015) Martin Hruska et al.   NATURE NEUROSCIENCE

A Secreted Tyrosine Kinase Acts in the Extracellular Environment

(2014) Mattia R. Bordoli et al.   CELL

Activity-Driven Local ATP Synthesis Is Required for Synaptic Function

(2014) Vidhya Rangaraju et al.   CELL

EphrinB-EphB receptor signaling contributes to bone cancer pain via Toll-like receptor and proinflammatory cytokines in rat spinal cord

(2013) Su Liu et al.   PAIN

Antinociception and prevention of hyperalgesia by intrathecal administration of Ro 25-6981, a highly selective antagonist of the 2B subunit of N-methyl-d-aspartate receptor

(2013) Ming Jiang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Involvement of EphB1 Receptors Signalling in Models of Inflammatory and Neuropathic Pain

(2013) Vincent Cibert-Goton et al.   PLoS One

Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5

(2013) Kai Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disrupted surface cross-talk between NMDA and Ephrin-B2 receptors in anti-NMDA encephalitis

(2012) Lenka Mikasova et al.   BRAIN

Neuroligin-1 controls synaptic abundance of NMDA-type glutamate receptors through extracellular coupling

(2012) E. C. Budreck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Secreted Kinase Phosphorylates Extracellular Proteins That Regulate Biomineralization

(2012) V. S. Tagliabracci et al.   SCIENCE

Extracellular Phosphorylation and Phosphorylated Proteins: Not Just Curiosities But Physiologically Important

(2012) G. Yalak et al.   Science Signaling

Secreted protein kinases

(2012) Vincent S. Tagliabracci et al.   TRENDS IN BIOCHEMICAL SCIENCES

EphBs: an integral link between synaptic function and synaptopathies

(2012) Sean I. Sheffler-Collins et al.   TRENDS IN NEUROSCIENCES

Blocking EphB1 Receptor Forward Signaling in Spinal Cord Relieves Bone Cancer Pain and Rescues Analgesic Effect of Morphine Treatment in Rodents

(2011) S. Liu et al.   CANCER RESEARCH

Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease

(2011) Sathish Kumar et al.   EMBO JOURNAL

Spinal Protein Kinase M   Underlies the Maintenance Mechanism of Persistent Nociceptive Sensitization

(2011) M. N. Asiedu et al.   JOURNAL OF NEUROSCIENCE

EphB Controls NMDA Receptor Function and Synaptic Targeting in a Subunit-Specific Manner

(2011) M. J. Nolt et al.   JOURNAL OF NEUROSCIENCE

Involvement of EphB1 receptor/ephrinB1 ligand in bone cancer pain

(2011) Yan Dong et al.   NEUROSCIENCE LETTERS

Eph/ephrin molecules--a hub for signaling and endocytosis

(2010) M. E. Pitulescu et al.   GENES & DEVELOPMENT

Nociceptor-Expressed Ephrin-B2 Regulates Inflammatory and Neuropathic Pain

(2010) Jing Zhao et al.   Molecular Pain

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

(2010) Moustapha Cissé et al.   NATURE

Architecture of Eph receptor clusters

(2010) J. P. Himanen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The novel protein kinase Vlk is essential for stromal function of mesenchymal cells

(2009) M. Kinoshita et al.   DEVELOPMENT

Ephrin-B1 and ephrin-B2 mediate EphB-dependent presynaptic development via syntenin-1

(2009) A. C. McClelland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of Nogo Receptors Suppresses Nogo Signaling, Allowing Neurite Regeneration

(2009) Y. Takei   Science Signaling

Upregulation and redistribution of ephrinB and EphB receptor in dorsal root ganglion and spinal dorsal horn neurons after peripheral nerve injury and dorsal rhizotomy

(2008) Xue-Jun Song et al.   EUROPEAN JOURNAL OF PAIN

Pre-synaptic and post-synaptic localization of EphA4 and EphB2 in adult mouse forebrain

(2008) David Bouvier et al.   JOURNAL OF NEUROCHEMISTRY

EphB Receptors Couple Dendritic Filopodia Motility to Synapse Formation

(2008) Matthew S. Kayser et al.   NEURON

Regulation of NMDA receptor subunit expression and its implications for LTD, LTP, and metaplasticity

(2008) Koji Yashiro et al.   NEUROPHARMACOLOGY

EphrinB2 induces tyrosine phosphorylation of NR2B via Src-family kinases during inflammatory hyperalgesia

(2008) S. Slack et al.   NEUROSCIENCE

EphrinB-EphB receptor signaling contributes to neuropathic pain by regulating neural excitability and spinal synaptic plasticity in rats

(2008) Xue-Jun Song et al.   PAIN

Four-jointed Is a Golgi Kinase That Phosphorylates a Subset of Cadherin Domains

(2008) H. O. Ishikawa et al.   SCIENCE

Fiber-coupled light-emitting diode for localized photostimulation of neurons expressing channelrhodopsin-2

(2007) Luke Campagnola et al.   JOURNAL OF NEUROSCIENCE METHODS