标题
Concentration gradient generation methods based on microfluidic systems
作者
关键词
-
出版物
RSC Advances
Volume 7, Issue 48, Pages 29966-29984
出版商
Royal Society of Chemistry (RSC)
发表日期
2017-06-09
DOI
10.1039/c7ra04494a
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A review of chemical gradient systems for cell analysis
- (2016) Himali Somaweera et al. ANALYTICA CHIMICA ACTA
- Antibiograms in five pipetting steps: precise dilution assays in sub-microliter volumes with a conventional pipette
- (2016) Ladislav Derzsi et al. LAB ON A CHIP
- A highly addressable static droplet array enabling digital control of a single droplet at pico-volume resolution
- (2016) Heon-Ho Jeong et al. LAB ON A CHIP
- High-throughput single cell multidrug resistance analysis with multifunctional gradients-customizing microfluidic device
- (2016) Yiwei Li et al. SENSORS AND ACTUATORS B-CHEMICAL
- Droplet coalescence at microchannel intersection chambers with different shapes
- (2016) Zhaomiao Liu et al. Soft Matter
- On-chip dilution in nanoliter droplets
- (2015) Raviraj Thakur et al. ANALYST
- On-chip gradient generation in 256 microfluidic cell cultures: simulation and experimental validation
- (2015) Himali Somaweera et al. ANALYST
- 3D Droplet Microfluidic Systems for High-Throughput Biological Experimentation
- (2015) Dong-Ku Kang et al. ANALYTICAL CHEMISTRY
- Rapid modulation of droplet composition with pincer microvalves
- (2015) Christopher J. Ochs et al. LAB ON A CHIP
- A droplet microchip with substance exchange capability for the developmental study of C. elegans
- (2015) Hui Wen et al. LAB ON A CHIP
- Generation of stable orthogonal gradients of chemical concentration and substrate stiffness in a microfluidic device
- (2015) S. García et al. LAB ON A CHIP
- The microenvironment of double emulsions in rectangular microchannels
- (2015) Shaohua Ma et al. LAB ON A CHIP
- A programmable microfluidic static droplet array for droplet generation, transportation, fusion, storage, and retrieval
- (2015) Si Hyung Jin et al. LAB ON A CHIP
- Microfluidic static droplet array for analyzing microbial communication on a population gradient
- (2015) Heon-Ho Jeong et al. LAB ON A CHIP
- Polymer Brushes Patterned with Micrometer-Scale Chemical Gradients Using Laminar Co-Flow
- (2014) Hyung-Jun Koo et al. ACS Applied Materials & Interfaces
- Mixed hydrogel bead-based tumor spheroid formation and anticancer drug testing
- (2014) Yaolei Wang et al. ANALYST
- Interfacing Microwells with Nanoliter Compartments: A Sampler Generating High-Resolution Concentration Gradients for Quantitative Biochemical Analyses in Droplets
- (2014) Fabrice Gielen et al. ANALYTICAL CHEMISTRY
- Electrocoalescence based serial dilution of microfluidic droplets
- (2014) Biddut Bhattacharjee et al. Biomicrofluidics
- Coalescing drops in microfluidic parking networks: A multifunctional platform for drop-based microfluidics
- (2014) Swastika S. Bithi et al. Biomicrofluidics
- Characterising the effect of geometry on a microchamber for producing controlled concentration gradients
- (2014) Katherine Glover et al. CHEMICAL ENGINEERING SCIENCE
- Small-molecule axon-polarization studies enabled by a shear-free microfluidic gradient generator
- (2014) Hui Xu et al. LAB ON A CHIP
- On the flow topology inside droplets moving in rectangular microchannels
- (2014) Shaohua Ma et al. LAB ON A CHIP
- A polydimethylsiloxane–polycarbonate hybrid microfluidic device capable of generating perpendicular chemical and oxygen gradients for cell culture studies
- (2014) Chia-Wen Chang et al. LAB ON A CHIP
- Generation of tunable and pulsatile concentration gradients via microfluidic network
- (2014) Bingpu Zhou et al. Microfluidics and Nanofluidics
- The present and future role of microfluidics in biomedical research
- (2014) Eric K. Sackmann et al. NATURE
- Stationary nanoliter droplet array with a substrate of choice for single adherent/nonadherent cell incubation and analysis
- (2014) J. Shemesh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integrated pneumatic micro-pumps for high-throughput droplet-based microfluidics
- (2014) Jae-Won Choi et al. RSC Advances
- Generation of a chemical gradient across an array of 256 cell cultures in a single chip
- (2013) Himali Somaweera et al. ANALYST
- A Fully Unsupervised Compartment-on-Demand Platform for Precise Nanoliter Assays of Time-Dependent Steady-State Enzyme Kinetics and Inhibition
- (2013) Fabrice Gielen et al. ANALYTICAL CHEMISTRY
- Generation of Chemical Concentration Gradients in Mobile Droplet Arrays via Fragmentation of Long Immiscible Diluting Plugs
- (2013) Meng Sun et al. ANALYTICAL CHEMISTRY
- Droplet-Based Microfluidic Platform for High-Throughput, Multi-Parameter Screening of Photosensitizer Activity
- (2013) Soongwon Cho et al. ANALYTICAL CHEMISTRY
- A microfluidic localized, multiple cell culture array using vacuum actuated cell seeding: integrated anticancer drug testing
- (2013) Yan Gao et al. BIOMEDICAL MICRODEVICES
- Block-and-break generation of microdroplets with fixed volume
- (2013) Volkert van Steijn et al. Biomicrofluidics
- Stepwise reagent introduction-based droplet platform for multiplexed DNA sensing
- (2013) Xia Xiang et al. BIOSENSORS & BIOELECTRONICS
- Microfluidic traps for hard-wired operations on droplets
- (2013) Piotr M. Korczyk et al. LAB ON A CHIP
- Flow-switching allows independently programmable, extremely stable, high-throughput diffusion-based gradients
- (2013) Tino Frank et al. LAB ON A CHIP
- Combinatorial generation of droplets by controlled assembly and coalescence
- (2013) Eujin Um et al. LAB ON A CHIP
- Multiplex analysis of enzyme kinetics and inhibition by droplet microfluidics using picoinjectors
- (2013) Staffan L. Sjostrom et al. LAB ON A CHIP
- A microfluidic concentration-gradient droplet array generator for the production of multi-color nanoparticles
- (2013) Chun-Guang Yang et al. LAB ON A CHIP
- A microfluidic cell culture array with various oxygen tensions
- (2013) Chien-Chung Peng et al. LAB ON A CHIP
- A simple and versatile microfluidic cell density gradient generator for quantum dot cytotoxicity assay
- (2013) Jing Wu et al. LAB ON A CHIP
- Engineering microfluidic concentration gradient generators for biological applications
- (2013) Alicia G. G. Toh et al. Microfluidics and Nanofluidics
- Controlled dispensing and mixing of pico- to nanoliter volumes using on-demand droplet-based microfluidics
- (2013) Xuefei Sun et al. Microfluidics and Nanofluidics
- A facile on-demand droplet microfluidic system for lab-on-a-chip applications
- (2013) Hongbo Zhou et al. Microfluidics and Nanofluidics
- Droplet microfluidics driven by gradients of confinement
- (2013) R. Dangla et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microfluidic flow-free generation of chemical concentration gradients
- (2013) Yao Zhou et al. SENSORS AND ACTUATORS B-CHEMICAL
- On-Site Formation of Emulsions by Controlled Air Plugs
- (2013) Xiaowen Huang et al. Small
- Microdroplet coalescences at microchannel junctions with different collision angles
- (2012) Kai Wang et al. AICHE JOURNAL
- Temporal gradients in microfluidic systems to probe cellular dynamics: A review
- (2012) Raghuram Dhumpa et al. ANALYTICA CHIMICA ACTA
- Spatially selective reagent delivery into cancer cells using a two-layer microfluidic culture system
- (2012) Yan Liu et al. ANALYTICA CHIMICA ACTA
- Microalgal motility measurement microfluidic chip for toxicity assessment of heavy metals
- (2012) Guoxia Zheng et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- High-Throughput Analysis of Protein–Protein Interactions in Picoliter-Volume Droplets Using Fluorescence Polarization
- (2012) Jae-Won Choi et al. ANALYTICAL CHEMISTRY
- High-throughput study of alpha-synuclein expression in yeast using microfluidics for control of local cellular microenvironment
- (2012) Patrícia Rosa et al. Biomicrofluidics
- Overexpression of chemokine ligand 7 is associated with the progression of canine transmissible venereal tumor
- (2012) Hsin-Chien Chiang et al. BMC Veterinary Research
- Picoliter Cell Lysate Assays in Microfluidic Droplet Compartments for Directed Enzyme Evolution
- (2012) Balint Kintses et al. CHEMISTRY & BIOLOGY
- A microfluidic concentration generator for dose-response assays on ion channel pharmacology
- (2012) Chang-Yu Chen et al. LAB ON A CHIP
- A microfluidic device that forms and redirects pheromone gradients to study chemotropism in yeast
- (2012) Marie-Elena Brett et al. LAB ON A CHIP
- Automated generation of libraries of nL droplets
- (2012) Tomasz S. Kaminski et al. LAB ON A CHIP
- Concentration landscape generators for shear free dynamic chemical stimulation
- (2012) Mathieu Morel et al. LAB ON A CHIP
- Blood plasma separation in a long two-phase plug flowing through disposable tubing
- (2012) Meng Sun et al. LAB ON A CHIP
- Rapid screening of antibiotic toxicity in an automated microdroplet system
- (2012) Krzysztof Churski et al. LAB ON A CHIP
- Chemotaxis of Cell Populations through Confined Spaces at Single-Cell Resolution
- (2012) ZiQiu Tong et al. PLoS One
- Ischemia/reperfusion injury of primary porcine cardiomyocytes in a low-shear microfluidic culture and analysis device
- (2011) Grishma Khanal et al. ANALYST
- Multifunctional Picoliter Droplet Manipulation Platform and Its Application in Single Cell Analysis
- (2011) Shu-Qing Gu et al. ANALYTICAL CHEMISTRY
- Creation of Stepwise Concentration Gradient in Picoliter Droplets for Parallel Reactions of Matrix Metalloproteinase II and IX
- (2011) Sachin Jambovane et al. ANALYTICAL CHEMISTRY
- Enzyme Kinetic Measurements Using a Droplet-Based Microfluidic System with a Concentration Gradient
- (2011) Minh-Phuong Ngoc Bui et al. ANALYTICAL CHEMISTRY
- Droplet-Based Microfluidic Flow Injection System with Large-Scale Concentration Gradient by a Single Nanoliter-Scale Injection for Enzyme Inhibition Assay
- (2011) Long-Fei Cai et al. ANALYTICAL CHEMISTRY
- Sprouting Angiogenesis under a Chemical Gradient Regulated by Interactions with an Endothelial Monolayer in a Microfluidic Platform
- (2011) Gi Seok Jeong et al. ANALYTICAL CHEMISTRY
- Real-time luminescence-based colorimetric determination of double-strand DNA in droplet on demand
- (2011) Xia Xiang et al. BIOSENSORS & BIOELECTRONICS
- An integrated microfluidic culture device to regulate endothelial cell differentiation from embryonic stem cells
- (2011) Jong Min Lee et al. ELECTROPHORESIS
- Assay for molecular transport across gap junction channels in one-dimensional cell arrays
- (2011) Nannan Ye et al. LAB ON A CHIP
- Rapid spatial and temporal controlled signal delivery over large cell culture areas
- (2011) Jules J. VanDersarl et al. LAB ON A CHIP
- Microfluidic static droplet arrays with tuneable gradients in material composition
- (2011) Meng Sun et al. LAB ON A CHIP
- Coalescence-assisted generation of single nanoliter droplets with predefined composition
- (2011) Jonathan Shemesh et al. LAB ON A CHIP
- Combining rails and anchors with laser forcing for selective manipulation within 2D droplet arrays
- (2011) Etienne Fradet et al. LAB ON A CHIP
- Generation of oxygen gradients in microfluidic devices for cell culture using spatially confined chemical reactions
- (2011) Yung-Ann Chen et al. LAB ON A CHIP
- Uncovering toxicological complexity by multi-dimensional screenings in microsegmented flow: modulation of antibiotic interference by nanoparticles
- (2011) Jialan Cao et al. LAB ON A CHIP
- A robust diffusion-based gradient generator for dynamic cell assays
- (2011) Javier Atencia et al. LAB ON A CHIP
- Design of pressure-driven microfluidic networks using electric circuit analogy
- (2011) Kwang W. Oh et al. LAB ON A CHIP
- Droplet-based microfluidic device for multiple-droplet clustering
- (2011) Jing Xu et al. LAB ON A CHIP
- Generation of droplets with different concentrations using gradient-microfluidic droplet generator
- (2011) Chia-Hsien Yeh et al. Microfluidics and Nanofluidics
- A microdroplet dilutor for high-throughput screening
- (2011) Xize Niu et al. Nature Chemistry
- High-resolution dose-response screening using droplet-based microfluidics
- (2011) O. J. Miller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dendritic cell chemotaxis in 3D under defined chemokine gradients reveals differential response to ligands CCL21 and CCL19
- (2011) U. Haessler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microfabricated analytical systems for integrated cancer cytomics
- (2010) Donald Wlodkowic et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Automated Microfluidic Screening Assay Platform Based on DropLab
- (2010) Wen-Bin Du et al. ANALYTICAL CHEMISTRY
- Generation of Picoliter Droplets with Defined Contents and Concentration Gradients from the Separation of Chemical Mixtures
- (2010) Ashleigh B. Theberge et al. ANALYTICAL CHEMISTRY
- Microfluidic Serial Dilution Cell-Based Assay for Analyzing Drug Dose Response over a Wide Concentration Range
- (2010) Shinji Sugiura et al. ANALYTICAL CHEMISTRY
- High Throughput Assay of Diffusion through Cx43 Gap Junction Channels with a Microfluidic Chip
- (2010) Cédric Bathany et al. ANALYTICAL CHEMISTRY
- Valve-based microfluidic device for droplet on-demand operation and static assay
- (2010) Feng Guo et al. APPLIED PHYSICS LETTERS
- 2-layer based microfluidic concentration generator by hybrid serial and volumetric dilutions
- (2010) Kangsun Lee et al. BIOMEDICAL MICRODEVICES
- A low resistance microfluidic system for the creation of stable concentration gradients in a defined 3D microenvironment
- (2010) Ovid C. Amadi et al. BIOMEDICAL MICRODEVICES
- Microfluidic platform for chemotaxis in gradients formed by CXCL12 source-sink cells
- (2010) Yu-suke Torisawa et al. Integrative Biology
- Chemical neurostimulation using pulse code modulation (PCM) microfluidic chips
- (2010) Farouk Azizi et al. JOURNAL OF NEUROSCIENCE METHODS
- Chemical stimulation of the Arabidopsis thaliana root using multi-laminar flow on a microfluidic chip
- (2010) Matthias Meier et al. LAB ON A CHIP
- Microfluidic device generating stable concentration gradients for long term cell culture: application to Wnt3a regulation of β-catenin signaling
- (2010) Elisa Cimetta et al. LAB ON A CHIP
- Novel PDMS cylindrical channels that generate coaxial flow, and application to fabrication of microfibers and particles
- (2010) Edward Kang et al. LAB ON A CHIP
- High-throughput automated droplet microfluidic system for screening of reaction conditions
- (2010) Krzysztof Churski et al. LAB ON A CHIP
- An automated two-phase microfluidic system for kinetic analyses and the screening of compound libraries
- (2010) Jenifer Clausell-Tormos et al. LAB ON A CHIP
- Droplet microfluidics for characterizing the neurotoxin-induced responses in individual Caenorhabditis elegans
- (2010) Weiwei Shi et al. LAB ON A CHIP
- Dynamics of microfluidic droplets
- (2010) Charles N. Baroud et al. LAB ON A CHIP
- A high-throughput microfluidic assay to study neurite response to growth factor gradients
- (2010) Chandrasekhar R. Kothapalli et al. LAB ON A CHIP
- Bacterial Chemotaxis in Linear and Nonlinear Steady Microfluidic Gradients
- (2010) Tanvir Ahmed et al. NANO LETTERS
- Investigation of bacterial chemotaxis in flow-based microfluidic devices
- (2010) Derek L Englert et al. Nature Protocols
- Finite element modelling and design of a concentration gradient generating bioreactor: Application to biological pattern formation and toxicology
- (2010) Giovanni Vozzi et al. TOXICOLOGY IN VITRO
- Microfluidic Perfusion System for Automated Delivery of Temporal Gradients to Islets of Langerhans
- (2009) Xinyu Zhang et al. ANALYTICAL CHEMISTRY
- Electro-Coalescence of Digitally Controlled Droplets
- (2009) Xize Niu et al. ANALYTICAL CHEMISTRY
- Flow-Based Microfluidic Device for Quantifying Bacterial Chemotaxis in Stable, Competing Gradients
- (2009) D. L. Englert et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- An agarose-based microfluidic platform with a gradient buffer for 3D chemotaxis studies
- (2009) Ulrike Haessler et al. BIOMEDICAL MICRODEVICES
- Interstitial cell migration: integrin-dependent and alternative adhesion mechanisms
- (2009) Samuel Schmidt et al. CELL AND TISSUE RESEARCH
- Chemical gradient-mediated melting curve analysis for genotyping of SNPs
- (2009) Aman Russom et al. ELECTROPHORESIS
- Enhanced Transverse Migration of Bacteria by Chemotaxis in a Porous T-Sensor
- (2009) Tao Long et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Generation of complex concentration profiles by partial diffusive mixing in multi-stream laminar flow
- (2009) Yao Zhou et al. LAB ON A CHIP
- Optimisation and analysis of microreactor designs for microfluidic gradient generation using a purpose built optical detection system for entire chip imaging
- (2009) Hayat Abdulla Yusuf et al. LAB ON A CHIP
- Microvalve-actuated precise control of individual droplets in microfluidic devices
- (2009) Shaojiang Zeng et al. LAB ON A CHIP
- Simultaneous measurement of reactions in microdroplets filled by concentration gradients
- (2009) Nicolae Damean et al. LAB ON A CHIP
- The microfluidic palette: A diffusive gradient generator with spatio-temporal control
- (2009) Javier Atencia et al. LAB ON A CHIP
- Generation of arbitrary monotonic concentration profiles by a serial dilution microfluidic network composed of microchannels with a high fluidic-resistance ratio
- (2009) Koji Hattori et al. LAB ON A CHIP
- Optical imaging and analytical modelling of the dynamic concentration gradient of viscous inlet solutions in a microfabricated network design
- (2009) Hayat Abdulla Yusuf et al. MICROELECTRONIC ENGINEERING
- Systematic linearisation of a microfluidic gradient network with unequal solution inlet viscosities demonstrated using glycerol
- (2009) Hayat Abdulla Yusuf et al. Microfluidics and Nanofluidics
- Droplet microfluidic technology for single-cell high-throughput screening
- (2009) E. Brouzes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Simultaneous generation of multiple aqueous droplets in a microfluidic device
- (2008) Robert M. Lorenz et al. ANALYTICA CHIMICA ACTA
- A Digital Microfluidic Approach to Homogeneous Enzyme Assays
- (2008) Elizabeth M. Miller et al. ANALYTICAL CHEMISTRY
- An Integrated Device for Monitoring Time-Dependent in vitro Expression From Single Genes in Picolitre Droplets
- (2008) Fabienne Courtois et al. CHEMBIOCHEM
- Modular microfluidics for gradient generation
- (2008) Kang Sun et al. LAB ON A CHIP
- A microfluidics-based turning assay reveals complex growth cone responses to integrated gradients of substrate-bound ECM molecules and diffusible guidance cues
- (2008) C. Joanne Wang et al. LAB ON A CHIP
- Endothelial cell polarization and chemotaxis in a microfluidic device
- (2008) Amir Shamloo et al. LAB ON A CHIP
- A platform for assessing chemotactic migration within a spatiotemporally defined 3D microenvironment
- (2008) Vinay V. Abhyankar et al. LAB ON A CHIP
- Pillar-induced droplet merging in microfluidic circuits
- (2008) Xize Niu et al. LAB ON A CHIP
- Design, fabrication and implementation of a novel multi-parameter control microfluidic platform for three-dimensional cell culture and real-time imaging
- (2008) Vernella Vickerman et al. LAB ON A CHIP
- A serial dilution microfluidic device using a ladder network generating logarithmic or linear concentrations
- (2008) Choong Kim et al. LAB ON A CHIP
- Generalized serial dilution module for monotonic and arbitrary microfluidic gradient generators
- (2008) Kangsun Lee et al. LAB ON A CHIP
- Static microdroplet arrays: a microfluidic device for droplet trapping, incubation and release for enzymatic and cell-based assays
- (2008) Ansgar Huebner et al. LAB ON A CHIP
- Fabrication of a microfluidic chip containing dam, weirs and gradient generator for studying cellular response to chemical modulation
- (2008) Jing Ruan et al. Materials Science & Engineering C-Materials for Biological Applications
- Novel microsystems for concentration gradient generation through computer optimization with validation using optical instrumentation
- (2008) Hayat Abdulla Yusuf et al. MICROELECTRONIC ENGINEERING
- Robust Spatial Sensing of Mating Pheromone Gradients by Yeast Cells
- (2008) Travis I. Moore et al. PLoS One
- Microfluidic delivery of small molecules into mammalian cells based on hydrodynamic focusing
- (2007) Fen Wang et al. BIOTECHNOLOGY AND BIOENGINEERING
- Biomolecular gradients in cell culture systems
- (2007) Thomas M. Keenan et al. LAB ON A CHIP
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started