期刊
ANALYTICA CHIMICA ACTA
卷 907, 期 -, 页码 7-17出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.aca.2015.12.008
关键词
Gradient; Microfluidics; Lab on a chip; Review
资金
- Division Of Mathematical Sciences
- Direct For Mathematical & Physical Scien [1412796] Funding Source: National Science Foundation
Microfluidic spatial and temporal gradient generators have played an important role in many biological assays such as in the analysis of wound healing, inflammation, and cancer metastasis. Chemical gradient systems can also be applied to other fields such as drug design, chemical synthesis, chemotaxis, etc. Microfluidic systems are particularly amenable to gradient formation, as the length scales used in chips enable fluid processes that cannot be conducted in bulk scale. In this review we discuss new microfluidic devices for gradient generation and applications of those systems in cell analysis. (C) 2015 Elsevier B.V. All rights reserved.
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