Polydatin attenuates potassium oxonate-induced hyperuricemia and kidney inflammation by inhibiting NF-κB/NLRP3 inflammasome activation via the AMPK/SIRT1 pathway

The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway

(2016) Jiong Zhang et al.   BIOCHEMICAL PHARMACOLOGY

Polydatin Protecting Kidneys against Hemorrhagic Shock-Induced Mitochondrial DysfunctionviaSIRT1 Activation and p53 Deacetylation

(2016) Zhenhua Zeng et al.   Oxidative Medicine and Cellular Longevity

Thymol produces an antidepressant-like effect in a chronic unpredictable mild stress model of depression in mice

(2015) Xue-Yang Deng et al.   BEHAVIOURAL BRAIN RESEARCH

Targeting the NLRP3 Inflammasome to Reduce Diet-Induced Metabolic Abnormalities in Mice

(2015) Fausto Chiazza et al.   MOLECULAR MEDICINE

Mangiferin Attenuate Sepsis-Induced Acute Kidney Injury via Antioxidant and Anti-Inflammatory Effects

(2014) Liyu He et al.   AMERICAN JOURNAL OF NEPHROLOGY

The emerging role of the inflammasome in kidney diseases

(2014) Anthony Chang et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Is the inflammasome a potential therapeutic target in renal disease?

(2014) Clare M Turner et al.   BMC Nephrology

Polydatin ameliorates renal injury by attenuating oxidative stress-related inflammatory responses in fructose-induced urate nephropathic mice

(2012) Lvyi Chen et al.   FOOD AND CHEMICAL TOXICOLOGY

Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-κB signaling pathway in rat glomerular mesangial cells

(2012) Xi Xie et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Antihyperuricemic and nephroprotective effects of resveratrol and its analogues in hyperuricemic mice

(2012) Yun-Wei Shi et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Resveratrol Inhibits LPS-Induced MAPKs Activation via Activation of the Phosphatidylinositol 3-Kinase Pathway in Murine RAW 264.7 Macrophage Cells

(2012) Yi Zong et al.   PLoS One

Association between being African-American, serum urate levels and the risk of developing hyperuricemia: findings from the Coronary Artery Risk Development in Young Adults cohort

(2012) Angelo L Gaffo et al.   ARTHRITIS RESEARCH & THERAPY

Decreased extra-renal urate excretion is a common cause of hyperuricemia

(2012) Kimiyoshi Ichida et al.   Nature Communications

SIRT1 and AMPK in regulating mammalian senescence: A critical review and a working model

(2010) Yu Wang et al.   FEBS LETTERS

An Inflammasome-Independent Role for Epithelial-Expressed Nlrp3 in Renal Ischemia-Reperfusion Injury

(2010) A. A. Shigeoka et al.   JOURNAL OF IMMUNOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE