Polydatin Protecting Kidneys against Hemorrhagic Shock-Induced Mitochondrial DysfunctionviaSIRT1 Activation and p53 Deacetylation

Polydatin Inhibits Mitochondrial Dysfunction in the Renal Tubular Epithelial Cells of a Rat Model of Sepsis-Induced Acute Kidney Injury

(2015) Youguang Gao et al.   ANESTHESIA AND ANALGESIA

Polydatin protects hepatocytes against mitochondrial injury in acute severe hemorrhagic shock via SIRT1-SOD2pathway

(2015) Pengyun Li et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Polydatin Alleviates Small Intestine Injury during Hemorrhagic Shock as a SIRT1 Activator

(2015) Zhenhua Zeng et al.   Oxidative Medicine and Cellular Longevity

Melatonin receptor-mediated protection against myocardial ischemia/reperfusion injury: role of SIRT1

(2014) Liming Yu et al.   JOURNAL OF PINEAL RESEARCH

Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1

(2013) Xiao-hui Li et al.   MEDIATORS OF INFLAMMATION

Polydatin, a natural polyphenol, protects arterial smooth muscle cells against mitochondrial dysfunction and lysosomal destabilization following hemorrhagic shock

(2012) Xingmin Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Polydatin – a new mitochondria protector for acute severe hemorrhagic shock treatment

(2012) Xingmin Wang et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Sirtuins as regulators of metabolism and healthspan

(2012) Riekelt H. Houtkooper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone Deacetylases 6 and 9 and Sirtuin-1 Control Foxp3+ Regulatory T Cell Function Through Shared and Isoform-Specific Mechanisms

(2012) U. H. Beier et al.   Science Signaling

Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53

(2011) C. Zhang et al.   CARDIOVASCULAR RESEARCH

PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice

(2011) Mei Tran et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional Characterization of Apical Transporters Expressed in Rat Proximal Tubular Cells (PTCs) in Primary Culture

(2011) Takeo Nakanishi et al.   MOLECULAR PHARMACEUTICS

Cardioprotective effect of polydatin against ischemia/reperfusion injury: Roles of protein kinase C and mito KATP activation

(2011) Qing Miao et al.   PHYTOMEDICINE

Senescence and dysfunction of proximal tubular cells are associated with activated p53 expression by indoxyl sulfate

(2010) Hidehisa Shimizu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hypotensive Resuscitation Combined with Polydatin Improve Microcirculation and Survival in a Rabbit Model of Uncontrolled Hemorrhagic Shock in Pregnancy

(2009) Chao Sheng et al.   JOURNAL OF SURGICAL RESEARCH

The mitochondrial p53 pathway

(2008) Angelina V. Vaseva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS