A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling

GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling

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Persistent cAMP Signaling by Internalized LH Receptors in Ovarian Follicles

(2016) Sandra Lyga et al.   ENDOCRINOLOGY

β-Arrestin drives MAP kinase signalling from clathrin-coated structures after GPCR dissociation

(2016) K. Eichel et al.   NATURE CELL BIOLOGY

Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced bystander BRET

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G Protein-coupled Receptor (GPCR) Signaling via Heterotrimeric G Proteins from Endosomes

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Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression

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GPCR signaling along the endocytic pathway

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Differential Regulation of Endosomal GPCR/β-Arrestin Complexes and Trafficking by MAPK

(2014) Etienne Khoury et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endosomal generation of cAMP in GPCR signaling

(2014) Jean-Pierre Vilardaga et al.   Nature Chemical Biology

Advances in Analysis of Low Signal-to-Noise Images Link Dynamin and AP2 to the Functions of an Endocytic Checkpoint

(2013) François Aguet et al.   DEVELOPMENTAL CELL

Noncanonical Control of Vasopressin Receptor Type 2 Signaling by Retromer and Arrestin

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Pituitary Adenylate Cyclase 1 Receptor Internalization and Endosomal Signaling Mediate the Pituitary Adenylate Cyclase Activating Polypeptide-Induced Increase in Guinea Pig Cardiac Neuron Excitability

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Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide

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Conformational biosensors reveal GPCR signalling from endosomes

(2013) Roshanak Irannejad et al.   NATURE

Genome engineering using the CRISPR-Cas9 system

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Building a Better Dynasore: The Dyngo Compounds Potently Inhibit Dynamin and Endocytosis

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Pitstop 2 Is a Potent Inhibitor of Clathrin-Independent Endocytosis

(2012) Dipannita Dutta et al.   PLoS One

Differential  -Arrestin-Dependent Conformational Signaling and Cellular Responses Revealed by Angiotensin Analogs

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Role of the Clathrin Terminal Domain in Regulating Coated Pit Dynamics Revealed by Small Molecule Inhibition

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Molecular mechanism and physiological functions of clathrin-mediated endocytosis

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Endocytosis Promotes Rapid Dopaminergic Signaling

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β-arrestin-mediated receptor trafficking and signal transduction

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Role of ßarrestins in bradykinin B2 receptor-mediated signalling

(2010) Brandon Zimmerman et al.   CELLULAR SIGNALLING

A Novel Biased Allosteric Compound Inhibitor of Parturition Selectively Impedes the Prostaglandin F2α-mediated Rho/ROCK Signaling Pathway

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Pharmacological Chaperones Restore Function to MC4R Mutants Responsible for Severe Early-Onset Obesity

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Beyond Desensitization: Physiological Relevance of Arrestin-Dependent Signaling

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Signaling by internalized G-protein-coupled receptors

(2010) Davide Calebiro et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Inhibition of Dynamin Mediated Endocytosis by theDynoles—Synthesis and Functional Activity of a Family of Indoles

(2009) Timothy A. Hill et al.   JOURNAL OF MEDICINAL CHEMISTRY

Sustained cyclic AMP production by parathyroid hormone receptor endocytosis

(2009) Sébastien Ferrandon et al.   Nature Chemical Biology

Endocytosis and signalling: intertwining molecular networks

(2009) Alexander Sorkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Persistent cAMP-Signals Triggered by Internalized G-Protein–Coupled Receptors

(2009) Davide Calebiro et al.   PLOS BIOLOGY

c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway

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Regulation of GPCRs by Endocytic Membrane Trafficking and Its Potential Implications

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