Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors

Pathogen-derived extracellular vesicles coordinate social behaviour and host manipulation

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Extracellular Vesicles: Unique Intercellular Delivery Vehicles

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Crosstalk between Cytoplasmic RIG-I and STING Sensing Pathways

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Malaria Parasites Distribute Subversive Messages across Enemy Lines

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IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP

(2017) K. L. Jønsson et al.   Nature Communications

Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense

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Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

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Malaria: Biology and Disease

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Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality

(2016) Xiao Yu et al.   IMMUNITY

cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signaling

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Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing

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Sensing of latent EBV infection through exosomal transfer of 5′pppRNA

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Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria

(2016) Pierre-Yves Mantel et al.   Nature Communications

Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4

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Type I Interferons Regulate Immune Responses in Humans with Blood-Stage Plasmodium falciparum Infection

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Cytosolic Innate Immune Sensing and Signaling upon Infection

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Profiling of small RNA cargo of extracellular vesicles shed by Trypanosoma cruzi reveals a specific extracellular signature

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A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis

(2015) Bappaditya Dey et al.   NATURE MEDICINE

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

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Innate immune recognition of DNA: A recent history

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Induction of Interferon-Stimulated Genes by IRF3 Promotes Replication of Toxoplasma gondii

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Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment

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Double-stranded DNA in exosomes: a novel biomarker in cancer detection

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Cytosolic RNA:DNA hybrids activate the cGAS–STING axis

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Exosomes and other extracellular vesicles in host-pathogen interactions

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Identification of Double-stranded Genomic DNA Spanning All Chromosomes with MutatedKRASandp53DNA in the Serum Exosomes of Patients with Pancreatic Cancer

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Type I IFN signaling in CD8– DCs impairs Th1-dependent malaria immunity

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Emerging role of extracellular vesicles in inflammatory diseases

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Strain-specific innate immune signaling pathways determine malaria parasitemia dynamics and host mortality

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Bacterial Vesicles in Marine Ecosystems

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Causal analysis approaches in Ingenuity Pathway Analysis

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Cell-Cell Communication between Malaria-Infected Red Blood Cells via Exosome-like Vesicles

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Malaria-Infected Erythrocyte-Derived Microvesicles Mediate Cellular Communication within the Parasite Population and with the Host Immune System

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Toll-Like Receptor 7 Mediates Early Innate Immune Responses to Malaria

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Extracellular vesicles: Exosomes, microvesicles, and friends

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A pathogenic picornavirus acquires an envelope by hijacking cellular membranes

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Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

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PfSET10, a Plasmodium falciparum Methyltransferase, Maintains the Active var Gene in a Poised State during Parasite Division

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Prion-infected cells regulate the release of exosomes with distinct ultrastructural features

(2012) Bradley M. Coleman et al.   FASEB JOURNAL

TLR9 and MyD88 Are Crucial for the Development of Protective Immunity to Malaria

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STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway

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Distinct innate immune responses in human macrophages and endothelial cells infected with shrew-borne hantaviruses

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Exosomes: Vehicles for the Transfer of Toxic Proteins Associated with Neurodegenerative Diseases?

(2012) Shayne A. Bellingham et al.   Frontiers in Physiology

Horizontal Transfer of the OXA-24 Carbapenemase Gene via Outer Membrane Vesicles: a New Mechanism of Dissemination of Carbapenem Resistance Genes in Acinetobacter baumannii

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Exosomes as intercellular signalosomes and pharmacological effectors

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Innate Immune Recognition of an AT-Rich Stem-Loop DNA Motif in the Plasmodium falciparum Genome

(2011) Shruti Sharma et al.   IMMUNITY

Circulating Red Cell–derived Microparticles in Human Malaria

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Exosomes from Plasmodium yoelii-Infected Reticulocytes Protect Mice from Lethal Infections

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C2C12 myoblasts release micro-vesicles containing mtDNA and proteins involved in signal transduction

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Augmented plasma microparticles during acute Plasmodium vivax infection

(2010) Fernanda MF Campos et al.   MALARIA JOURNAL

IFI16 is an innate immune sensor for intracellular DNA

(2010) Leonie Unterholzner et al.   NATURE IMMUNOLOGY

Functional delivery of viral miRNAs via exosomes

(2010) D. M. Pegtel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Malaria Parasite Development in the Mosquito and Infection of the Mammalian Host

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Potential epigenetic regulatory proteins localise to distinct nuclear sub-compartments in Plasmodium falciparum

(2009) Jennifer Volz et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Astrocytes and Glioblastoma cells release exosomes carrying mtDNA

(2009) Michele Guescini et al.   JOURNAL OF NEURAL TRANSMISSION

A novel and universal method for microRNA RT-qPCR data normalization

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Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense

(2008) Shida Yousefi et al.   NATURE MEDICINE