标题
Allosteric cross-talk in chromatin can mediate drug-drug synergy
作者
关键词
-
出版物
Nature Communications
Volume 8, Issue -, Pages 14860
出版商
Springer Nature
发表日期
2017-03-30
DOI
10.1038/ncomms14860
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- An Organometallic Compound which Exhibits a DNA Topology-Dependent One-Stranded Intercalation Mode
- (2016) Zhujun Ma et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Effects of MacroH2A and H2A.Z on Nucleosome Dynamics as Elucidated by Molecular Dynamics Simulations
- (2016) Samuel Bowerman et al. BIOPHYSICAL JOURNAL
- Emerging Computational Methods for the Rational Discovery of Allosteric Drugs
- (2016) Jeffrey R. Wagner et al. CHEMICAL REVIEWS
- Recognition of the nucleosome by chromatin factors and enzymes
- (2016) Robert K McGinty et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations
- (2016) Giulia Palermo et al. ACS Central Science
- Fighting Cancer with Transition Metal Complexes: From Naked DNA to Protein and Chromatin Targeting Strategies
- (2015) Giulia Palermo et al. ChemMedChem
- Histone exchange, chromatin structure and the regulation of transcription
- (2015) Swaminathan Venkatesh et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Dynamics-Driven Allostery in Protein Kinases
- (2015) Alexandr P. Kornev et al. TRENDS IN BIOCHEMICAL SCIENCES
- Nucleosome Structure and Function
- (2014) Robert K. McGinty et al. CHEMICAL REVIEWS
- Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome
- (2014) Robert K. McGinty et al. NATURE
- The ensemble nature of allostery
- (2014) Hesam N. Motlagh et al. NATURE
- Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders
- (2014) P. Jeffrey Conn et al. NATURE REVIEWS DRUG DISCOVERY
- In vivo anti-tumor activity of the organometallic ruthenium(ii)-arene complex [Ru(η6-p-cymene)Cl2(pta)] (RAPTA-C) in human ovarian and colorectal carcinomas
- (2014) Andrea Weiss et al. Chemical Science
- Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity
- (2014) Zenita Adhireksan et al. Nature Communications
- Allostery in Disease and in Drug Discovery
- (2013) Ruth Nussinov et al. CELL
- The mode of action of anticancer gold-based drugs: a structural perspective
- (2013) Luigi Messori et al. CHEMICAL COMMUNICATIONS
- Novel metal(ii) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
- (2013) Samuel M. Meier et al. Chemical Science
- Understanding the mechanism of cytochrome P450 3A4: recent advances and remaining problems
- (2012) Irina F. Sevrioukova et al. DALTON TRANSACTIONS
- The biological activity of auranofin: implications for novel treatment of diseases
- (2012) J. M. Madeira et al. INFLAMMOPHARMACOLOGY
- A Ruthenium Antimetastasis Agent Forms Specific Histone Protein Adducts in the Nucleosome Core
- (2011) Bin Wu et al. CHEMISTRY-A EUROPEAN JOURNAL
- Organometallic Ruthenium(II) Arene Compounds with Antiangiogenic Activity
- (2011) Patrycja Nowak-Sliwinska et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structural Basis of Silencing: Sir3 BAH Domain in Complex with a Nucleosome at 3.0 A Resolution
- (2011) K.-J. Armache et al. SCIENCE
- Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
- (2010) T.-C. Chou CANCER RESEARCH
- Nucleosome structural studies
- (2010) Song Tan et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Structure of RCC1 chromatin factor bound to the nucleosome core particle
- (2010) Ravindra D. Makde et al. NATURE
- Synergistic drug combinations tend to improve therapeutically relevant selectivity
- (2009) Joseph Lehár et al. NATURE BIOTECHNOLOGY
- Mechanisms of drug combinations: interaction and network perspectives
- (2009) Jia Jia et al. NATURE REVIEWS DRUG DISCOVERY
- Influence of the Diketonato Ligand on the Cytotoxicities of [Ru(η6-p-cymene)(R2acac)(PTA)]+ Complexes (PTA = 1,3,5-triaza-7-phosphaadamantane)
- (2008) Carsten A. Vock et al. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
- DNA Structural Distortions Induced by Ruthenium−Arene Anticancer Compounds
- (2008) Christian Gossens et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started