IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2
出版年份 2017 全文链接
标题
IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2
作者
关键词
-
出版物
Nature Communications
Volume 8, Issue -, Pages 14647
出版商
Springer Nature
发表日期
2017-03-17
DOI
10.1038/ncomms14647
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies
- (2015) Cindy S. Ma et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms
- (2015) Katerina Hatzi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-21 and IL-4 Collaborate To Shape T-Dependent Antibody Responses
- (2015) H. M. McGuire et al. JOURNAL OF IMMUNOLOGY
- Human IL-21 and IL-21R deficiencies
- (2014) Daniel Kotlarz et al. CURRENT OPINION IN PEDIATRICS
- Extending the clinical and immunological phenotype of human interleukin-21 receptor deficiency
- (2014) P. Stepensky et al. HAEMATOLOGICA
- Early-onset inflammatory bowel disease and common variable immunodeficiency–like disease caused by IL-21 deficiency
- (2014) Elisabeth Salzer et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Circulating T follicular regulatory and helper cells have memory-like properties
- (2014) Peter T. Sage et al. JOURNAL OF CLINICAL INVESTIGATION
- Release from Regulatory T Cell-Mediated Suppression during the Onset of Tissue-Specific Autoimmunity Is Associated with Elevated IL-21
- (2014) L. E. Clough et al. JOURNAL OF IMMUNOLOGY
- Interleukin-21 Promotes Germinal Center Reaction by Skewing the Follicular Regulatory T Cell to Follicular Helper T Cell Balance in Autoimmune BXD2 Mice
- (2014) Yanna Ding et al. Arthritis & Rheumatology
- Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome
- (2013) Daniel Kotlarz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Insights into the Role of Bcl6 in Follicular Th Cells Using a New Conditional Mutant Mouse Model
- (2013) K. Hollister et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: STAT1 Is Required for IL-6-Mediated Bcl6 Induction for Early Follicular Helper Cell Differentiation
- (2013) Y. S. Choi et al. JOURNAL OF IMMUNOLOGY
- Interleukin-21 Is a Critical Cytokine for the Generation of Virus-Specific Long-Lived Plasma Cells
- (2013) M. A. U. Rasheed et al. JOURNAL OF VIROLOGY
- IL-21 Restricts Virus-driven Treg Cell Expansion in Chronic LCMV Infection
- (2013) Iwana Schmitz et al. PLoS Pathogens
- IL-21 inhibits T cell IL-2 production and impairs Treg homeostasis
- (2012) K. Attridge et al. BLOOD
- Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation
- (2012) André Ballesteros-Tato et al. IMMUNITY
- STAT5 Protein Negatively Regulates T Follicular Helper (Tfh) Cell Generation and Function
- (2012) Roza I. Nurieva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bcl6 expression specifies the T follicular helper cell program in vivo
- (2012) Xindong Liu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- STAT5 is a potent negative regulator of TFHcell differentiation
- (2012) Robert J. Johnston et al. JOURNAL OF EXPERIMENTAL MEDICINE
- B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1
- (2012) Alex Karnowski et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Bcl6 and Maf Cooperate To Instruct Human Follicular Helper CD4 T Cell Differentiation
- (2012) M. A. Kroenke et al. JOURNAL OF IMMUNOLOGY
- Single and Coexpression of CXCR4 and CXCR5 Identifies CD4 T Helper Cells in Distinct Lymph Node Niches during Influenza Virus Infection
- (2012) R. A. Elsner et al. JOURNAL OF VIROLOGY
- The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood
- (2012) Peter T Sage et al. NATURE IMMUNOLOGY
- The development and fate of follicular helper T cells defined by an IL-21 reporter mouse
- (2012) Katja Lüthje et al. NATURE IMMUNOLOGY
- Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile
- (2012) Kenneth J Oestreich et al. NATURE IMMUNOLOGY
- Emerging patterns of genetic overlap across autoimmune disorders
- (2012) Corinne Richard-Miceli et al. Genome Medicine
- Regulation of the Germinal Center Reaction by Foxp3+ Follicular Regulatory T Cells
- (2011) I. Wollenberg et al. JOURNAL OF IMMUNOLOGY
- Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages
- (2011) Wei Liao et al. NATURE IMMUNOLOGY
- Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
- (2011) Yeonseok Chung et al. NATURE MEDICINE
- Foxp3+ follicular regulatory T cells control the germinal center response
- (2011) Michelle A Linterman et al. NATURE MEDICINE
- IL-21 and IL-6 Are Critical for Different Aspects of B Cell Immunity and Redundantly Induce Optimal Follicular Helper CD4 T Cell (Tfh) Differentiation
- (2011) Danelle Eto et al. PLoS One
- IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses
- (2010) Michelle A. Linterman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-21 regulates germinal center B cell differentiation and proliferation through a B cell–intrinsic mechanism
- (2010) Dimitra Zotos et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Expression, purification and characterization of recombinant interleukin-21
- (2010) Carol M.Y. Lee et al. JOURNAL OF IMMUNOLOGICAL METHODS
- The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment
- (2009) Di Yu et al. IMMUNITY
- Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation
- (2009) R. J. Johnston et al. SCIENCE
- Bcl6 Mediates the Development of T Follicular Helper Cells
- (2009) R. I. Nurieva et al. SCIENCE
- A Vital Role for Interleukin-21 in the Control of a Chronic Viral Infection
- (2009) J. S. Yi et al. SCIENCE
- IL-21 Is Required to Control Chronic Viral Infection
- (2009) H. Elsaesser et al. SCIENCE
- T Follicular Helper (TFH) Cells in Normal and Dysregulated Immune Responses
- (2008) Cecile King et al. Annual Review of Immunology
- A Fundamental Role for Interleukin-21 in the Generation of T Follicular Helper Cells
- (2008) Alexis Vogelzang et al. IMMUNITY
- ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity
- (2008) Jared M. Odegard et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Interleukin 21: a cytokine/cytokine receptor system that has come of age
- (2008) Warren J. Leonard et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Detecting shared pathogenesis from the shared genetics of immune-related diseases
- (2008) Alexandra Zhernakova et al. NATURE REVIEWS GENETICS
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