Loss of PHD3 in myeloid cells dampens the inflammatory response and fibrosis after hind-limb ischemia

Prolyl-4-hydroxylase 2 and 3 coregulate murine erythropoietin in brain pericytes

(2016) Andres A. Urrutia et al.   BLOOD

Hypoxia-dependent regulation of inflammatory pathways in immune cells

(2016) Cormac T. Taylor et al.   JOURNAL OF CLINICAL INVESTIGATION

PHD2 Is a Regulator for Glycolytic Reprogramming in Macrophages

(2016) Annemarie Guentsch et al.   MOLECULAR AND CELLULAR BIOLOGY

Short Hairpin RNA Silencing of PHD-2 Improves Neovascularization and Functional Outcomes in Diabetic Wounds and Ischemic Limbs

(2016) Kevin J. Paik et al.   PLoS One

Modulating the Vascular Response to Limb Ischemia: Angiogenic and Cell Therapies

(2015) J. P. Cooke et al.   CIRCULATION RESEARCH

Prostaglandin E2Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages

(2015) Milena Sokolowska et al.   JOURNAL OF IMMUNOLOGY

Molecular determinants of sterile inflammation

(2014) Hajime Kono et al.   CURRENT OPINION IN IMMUNOLOGY

Prolyl-4-hydroxylase domain 3 (PHD3) is a critical terminator for cell survival of macrophages under stress conditions

(2014) Lija Swain et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Targeting hypoxia signalling for the treatment of ischaemic and inflammatory diseases

(2014) Holger K. Eltzschig et al.   NATURE REVIEWS DRUG DISCOVERY

Molecular Mechanisms of Action and Therapeutic Uses of Pharmacological Inhibitors of HIF–Prolyl 4-Hydroxylases for Treatment of Ischemic Diseases

(2013) Vaithinathan Selvaraju et al.   ANTIOXIDANTS & REDOX SIGNALING

Pan-genomic binding of hypoxia-inducible transcription factors

(2013) Johannes Schödel et al.   BIOLOGICAL CHEMISTRY

The regulation, localization, and functions of oxygen-sensing prolyl hydroxylase PHD3

(2013) Panu M. Jaakkola et al.   BIOLOGICAL CHEMISTRY

The role of immune-related myeloid cells in angiogenesis

(2013) Sarah E.J. Chambers et al.   IMMUNOBIOLOGY

Cytochrome P4502S1: a novel monocyte/macrophage fatty acid epoxygenase in human atherosclerotic plaques

(2012) Timo Frömel et al.   BASIC RESEARCH IN CARDIOLOGY

The updated biology of hypoxia-inducible factor

(2012) Samantha N Greer et al.   EMBO JOURNAL

Loss of the Oxygen Sensor PHD3 Enhances the Innate Immune Response to Abdominal Sepsis

(2012) J. Kiss et al.   JOURNAL OF IMMUNOLOGY

Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice

(2011) Sarah R. Walmsley et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of Immune Responses by Prostaglandin E2

(2011) P. Kalinski   JOURNAL OF IMMUNOLOGY

Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis

(2011) Yukiji Takeda et al.   NATURE

Innate immune signaling in cardiac ischemia

(2011) Fatih Arslan et al.   Nature Reviews Cardiology

Human CYP2S1 Metabolizes Cyclooxygenase- and Lipoxygenase-Derived Eicosanoids

(2010) P. Bui et al.   DRUG METABOLISM AND DISPOSITION

Inhibition of Prolyl Hydroxylase Domain Proteins Promotes Therapeutic Revascularization

(2009) Céline Loinard et al.   CIRCULATION

A Feedback Loop Involving the Phd3 Prolyl Hydroxylase Tunes the Mammalian Hypoxic Response In Vivo

(2009) Y. A. Minamishima et al.   MOLECULAR AND CELLULAR BIOLOGY

Functional Characterization of Human Cytochrome P450 2S1 Using a Synthetic Gene-Expressed Protein in Escherichia coli

(2009) P. H. Bui et al.   MOLECULAR PHARMACOLOGY

Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia

(2009) Anne Limbourg et al.   Nature Protocols

In vivofunctions of the prolyl-4-hydroxylase domain oxygen sensors: direct route to the treatment of anaemia and the protection of ischaemic tissues

(2008) D. M. Katschinski   Acta Physiologica

The kinesin KIF1B  acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor

(2008) S. Schlisio et al.   GENES & DEVELOPMENT

Arachidonic acid cytochrome P450 epoxygenase pathway

(2008) Arthur A. Spector   JOURNAL OF LIPID RESEARCH

Prolyl Hydroxylase PHD3 Activates Oxygen-dependent Protein Aggregation

(2008) Krista Rantanen et al.   MOLECULAR BIOLOGY OF THE CELL

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL