标题
The updated biology of hypoxia-inducible factor
作者
关键词
-
出版物
EMBO JOURNAL
Volume 31, Issue 11, Pages 2448-2460
出版商
Wiley
发表日期
2012-05-04
DOI
10.1038/emboj.2012.125
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition
- (2012) Wenyu Zhou et al. EMBO JOURNAL
- The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity
- (2012) Norma Masson et al. EMBO REPORTS
- UCP2 Inhibits ROS-Mediated Apoptosis in A549 under Hypoxic Conditions
- (2012) Sanming Deng et al. PLoS One
- SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization
- (2011) Lydia W.S. Finley et al. CANCER CELL
- Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
- (2011) Weibo Luo et al. CELL
- Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
- (2011) Eric V. Dang et al. CELL
- HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway
- (2011) L Qiang et al. CELL DEATH AND DIFFERENTIATION
- UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells
- (2011) Jin Zhang et al. EMBO JOURNAL
- Hypoxia Increases Sirtuin 1 Expression in a Hypoxia-inducible Factor-dependent Manner
- (2011) Rui Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
- (2011) Sarah R. Walmsley et al. JOURNAL OF CLINICAL INVESTIGATION
- HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells
- (2011) Lewis Z. Shi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Repeated assessment of orthotopic glioma pO2 by multi-site EPR oximetry: A technique with the potential to guide therapeutic optimization by repeated measurements of oxygen
- (2011) Nadeem Khan et al. JOURNAL OF NEUROSCIENCE METHODS
- MicroRNA-155 Promotes Resolution of Hypoxia-Inducible Factor 1 Activity during Prolonged Hypoxia
- (2011) U. Bruning et al. MOLECULAR AND CELLULAR BIOLOGY
- Hypoxia-inducible factor-1α mRNA: a new target for destabilization by tristetraprolin in endothelial cells
- (2011) Sandrine Chamboredon et al. MOLECULAR BIOLOGY OF THE CELL
- The SirT3 Divining Rod Points to Oxidative Stress
- (2011) Eric L. Bell et al. MOLECULAR CELL
- Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation
- (2011) Weiwei Yang et al. NATURE
- SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production
- (2011) E L Bell et al. ONCOGENE
- Succinate Dehydrogenase Is a Direct Target of Sirtuin 3 Deacetylase Activity
- (2011) Lydia W. S. Finley et al. PLoS One
- Hypoxia-induced methylation of a pontin chromatin remodeling factor
- (2011) J. S. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth
- (2011) Q. Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interaction Between Notch and Hif- in Development and Survival of Drosophila Blood Cells
- (2011) T. Mukherjee et al. SCIENCE
- SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress
- (2010) Hyun-Seok Kim et al. CANCER CELL
- Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction
- (2010) Shinichi Someya et al. CELL
- The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α
- (2010) Lei Zhong et al. CELL
- Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation
- (2010) Xiaolei Qiu et al. Cell Metabolism
- The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
- (2010) Tugba Simsek et al. Cell Stem Cell
- Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells
- (2010) Keiyo Takubo et al. Cell Stem Cell
- Toxoplasma gondiiActivates Hypoxia-inducible Factor (HIF) by Stabilizing the HIF-1α Subunit via Type I Activin-like Receptor Kinase Receptor Signaling
- (2010) Mandi Wiley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress
- (2010) Randa Tao et al. MOLECULAR CELL
- Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α
- (2010) Ji-Hong Lim et al. MOLECULAR CELL
- Interaction of Hypoxia-Inducible Factor-1α and Notch Signaling Regulates Medulloblastoma Precursor Proliferation and Fate
- (2010) Francesca Pistollato et al. STEM CELLS
- Mitochondrial Function Controls Proliferation and Early Differentiation Potential of Embryonic Stem Cells
- (2010) Sudip Mandal et al. STEM CELLS
- Regulation of Succinate Dehydrogenase Activity by SIRT3 in Mammalian Mitochondria
- (2009) Huseyin Cimen et al. BIOCHEMISTRY
- Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion
- (2009) J Chen et al. BRITISH JOURNAL OF CANCER
- Naive and Primed Pluripotent States
- (2009) Jennifer Nichols et al. Cell Stem Cell
- Notch Signaling: The Core Pathway and Its Posttranslational Regulation
- (2009) Mark E. Fortini DEVELOPMENTAL CELL
- SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation
- (2009) Chao Huang et al. EMBO JOURNAL
- Activin Signaling: Effects on Body Composition and Mitochondrial Energy Metabolism
- (2009) Liunan Li et al. ENDOCRINOLOGY
- Differences in hydroxylation and binding of Notch and HIF-1α demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1)
- (2009) Sarah E. Wilkins et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Differentiation Stage-Specific Requirement in Hypoxia-Inducible Factor-1α–Regulated Glycolytic Pathway during Murine B Cell Development in Bone Marrow
- (2009) Hidefumi Kojima et al. JOURNAL OF IMMUNOLOGY
- Key Role for Activin B in Cellular Transformation after Loss of the von Hippel-Lindau Tumor Suppressor
- (2009) I. Wacker et al. MOLECULAR AND CELLULAR BIOLOGY
- HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
- (2009) Charles J. David et al. NATURE
- Regulation of endocytosis via the oxygen-sensing pathway
- (2009) Yi Wang et al. NATURE MEDICINE
- Regulation of Hypoxia-Inducible Factor 2 Signaling by the Stress-Responsive Deacetylase Sirtuin 1
- (2009) E. M. Dioum et al. SCIENCE
- Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth
- (2009) T. Hitosugi et al. Science Signaling
- Identification of Hypoxia-Inducible Factor-1 as a Novel Target for miR-17-92 MicroRNA Cluster
- (2008) A. Taguchi et al. CANCER RESEARCH
- Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
- (2008) William G. Kaelin et al. MOLECULAR CELL
- NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
- (2008) Jordi Rius et al. NATURE
- The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
- (2008) Heather R. Christofk et al. NATURE
- PCAF is an HIF-1α cofactor that regulates p53 transcriptional activity in hypoxia
- (2008) G Xenaki et al. ONCOGENE
- Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways
- (2008) X. Zheng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
- (2008) B.-H. Ahn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Notch signaling mediates hypoxia-induced tumor cell migration and invasion
- (2008) C. Sahlgren et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis
- (2007) Eoin P. Cummins et al. GASTROENTEROLOGY
- Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition
- (2007) Andreas Robinson et al. GASTROENTEROLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started