Metal-free C–H alkylation of heteroarenes with alkyltrifluoroborates: a general protocol for 1°, 2° and 3° alkylation

Photoredox Catalysis for the Generation of Carbon Centered Radicals

(2016) Jean-Philippe Goddard et al.   ACCOUNTS OF CHEMICAL RESEARCH

Manganese-Catalyzed Borylation of Unactivated Alkyl Chlorides

(2016) Thomas C. Atack et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-Electron Transmetalation: Photoredox/Nickel Dual Catalytic Cross-Coupling of Secondary Alkyl β-Trifluoroboratoketones and -esters with Aryl Bromides

(2016) John C. Tellis et al.   ORGANIC LETTERS

Visible Light Photoredox Cross-Coupling of Acyl Chlorides with Potassium Alkoxymethyltrifluoroborates: Synthesis of α-Alkoxyketones

(2016) Javad Amani et al.   ORGANIC LETTERS

Single-Electron Transmetalation: Protecting-Group-Independent Synthesis of Secondary Benzylic Alcohol Derivatives via Photoredox/Nickel Dual Catalysis

(2016) Rahman Karimi-Nami et al.   ORGANIC LETTERS

Direct alkylation of heteroarenes with unactivated bromoalkanes using photoredox gold catalysis

(2016) T. McCallum et al.   Chemical Science

Photoredox-mediated Minisci C–H alkylation of N-heteroarenes using boronic acids and hypervalent iodine

(2016) Guo-Xing Li et al.   Chemical Science

Donor–Acceptor Fluorophores for Visible-Light-Promoted Organic Synthesis: Photoredox/Ni Dual Catalytic C(sp3)–C(sp2) Cross-Coupling

(2016) Jian Luo et al.   ACS Catalysis

α-Arylation/Heteroarylation of Chiral α-Aminomethyltrifluoroborates by Synergistic Iridium Photoredox/Nickel Cross-Coupling Catalysis

(2015) Mirna El Khatib et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Single-Electron Transmetalation: Synthesis of 1,1-Diaryl-2,2,2-trifluoroethanes by Photoredox/Nickel Dual Catalytic Cross-Coupling

(2015) DaWeon Ryu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Applications of Fluorine in Medicinal Chemistry

(2015) Eric P. Gillis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Single-Electron Transmetalation: An Enabling Technology for Secondary Alkylboron Cross-Coupling

(2015) David N. Primer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alcohols as alkylating agents in heteroarene C–H functionalization

(2015) Jian Jin et al.   NATURE

Photoredox Cross-Coupling: Ir/Ni Dual Catalysis for the Synthesis of Benzylic Ethers

(2015) Idris Karakaya et al.   ORGANIC LETTERS

Amide and Amine Nucleophiles in Polar Radical Crossover Cycloadditions: Synthesis of γ-Lactams and Pyrrolidines

(2015) Nathan J. Gesmundo et al.   ORGANIC LETTERS

Protecting group-free, selective cross-coupling of alkyltrifluoroborates with borylated aryl bromides via photoredox/nickel dual catalysis

(2015) Yohei Yamashita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Divergent regioselectivity in photoredox-catalyzed hydrofunctionalization reactions of unsaturated amides and thioamides

(2015) Peter D. Morse et al.   Chemical Science

anti-Markovnikov Hydroamination of Alkenes Catalyzed by a Two-Component Organic Photoredox System: Direct Access to Phenethylamine Derivatives

(2014) Tien M. Nguyen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Late-Stage Functionalization of Biologically Active Heterocycles Through Photoredox Catalysis

(2014) Daniel A. DiRocco et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct α-Arylation of Ethers through the Combination of Photoredox-Mediated CH Functionalization and the Minisci Reaction

(2014) Jian Jin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Simple Sulfinate Synthesis Enables CH Trifluoromethylcyclopropanation

(2014) Ryan Gianatassio et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Transition Metal-Free Minisci Reaction: Acylation of Isoquinolines, Quinolines, and Quinoxaline

(2014) Yogesh Siddaraju et al.   JOURNAL OF ORGANIC CHEMISTRY

Palau’chlor: A Practical and Reactive Chlorinating Reagent

(2014) Rodrigo A. Rodriguez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Late-Stage Functionalization of Complex Molecules through C–H Fluorination and Nucleophilic Aromatic Substitution

(2014) Patrick S. Fier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Mild, Ferrocene-Catalyzed C–H Imidation of (Hetero)Arenes

(2014) Klement Foo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanistic Insight into the Photoredox Catalysis of Anti-Markovnikov Alkene Hydrofunctionalization Reactions

(2014) Nathan A. Romero et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Butyrolactone Synthesis via Polar Radical Crossover Cycloaddition Reactions: Diastereoselective Syntheses of Methylenolactocin and Protolichesterinic Acid

(2014) Mary A. Zeller et al.   ORGANIC LETTERS

Single-electron transmetalation in organoboron cross-coupling by photoredox/nickel dual catalysis

(2014) J. C. Tellis et al.   SCIENCE

Synthesis, Structure, and SAR of Tetrahydropyran-Based LpxC Inhibitors

(2014) Kerry E. Murphy-Benenato et al.   ACS Medicinal Chemistry Letters

Direct Synthesis of Fluorinated Heteroarylether Bioisosteres

(2013) Qianghui Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Highly Substituted Tetrahydrofurans by Catalytic Polar-Radical-Crossover Cycloadditions of Alkenes and Alkenols

(2013) Jean-Marc M. Grandjean et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silver catalyzed decarboxylative direct C2-alkylation of benzothiazoles with carboxylic acids

(2013) Wei-Ming Zhao et al.   CHEMICAL COMMUNICATIONS

Synthesis and Minisci Reactions of Organotrifluoroborato Building Blocks

(2013) Marc Presset et al.   JOURNAL OF ORGANIC CHEMISTRY

Anti-Markovnikov Hydroamination of Alkenes Catalyzed by an Organic Photoredox System

(2013) Tien M. Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Catalytic Anti-Markovnikov Addition of Carboxylic Acids to Alkenes

(2013) Andrew J. Perkowski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Uncovering the Mechanism of the Ag(I)/Persulfate-Catalyzed Cross-Coupling Reaction of Arylboronic Acids and Heteroarenes

(2013) Niki R. Patel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Radical-Based Regioselective C–H Functionalization of Electron-Deficient Heteroarenes: Scope, Tunability, and Predictability

(2013) Fionn O’Hara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Radical Route for the Alkylation of Purine Nucleosides at C6 via Minisci Reaction

(2013) Ran Xia et al.   ORGANIC LETTERS

One-Pot Three-Component Approach to the Synthesis of Polyfunctional Pyrazoles

(2013) Guolin Zhang et al.   ORGANIC LETTERS

Synthesis of cyclobutane lignans via an organic single electron oxidant–electron relay system

(2013) Michelle Riener et al.   Chemical Science

Catalytic hydrotrifluoromethylation of styrenes and unactivated aliphatic alkenes via an organic photoredox system

(2013) Dale J. Wilger et al.   Chemical Science

Recent Applications of Organic Dyes as Photoredox Catalysts in Organic Synthesis

(2013) David A. Nicewicz et al.   ACS Catalysis

Visible Light-Induced Selective Generation of Radicals from Organoborates by Photoredox Catalysis

(2012) Yusuke Yasu et al.   ADVANCED SYNTHESIS & CATALYSIS

Highly Reactive, Single-Component Nickel Catalyst Precursor for Suzuki-Miyuara Cross-Coupling of Heteroaryl Boronic Acids with Heteroaryl Halides

(2012) Shaozhong Ge et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Isoquinolines and Heterocycle-Fused Pyridines via Three-Component Cascade Reaction of Aryl Ketones, Hydroxylamine, and Alkynes

(2012) Liyao Zheng et al.   JOURNAL OF ORGANIC CHEMISTRY

Microwave-Assisted One-Pot Synthesis of Isoquinolines, Furopyridines, and Thienopyridines by Palladium-Catalyzed Sequential Coupling–Imination–Annulation of 2-Bromoarylaldehydes with Terminal Acetylenes and Ammonium Acetate

(2012) Dingqiao Yang et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct Catalytic Anti-Markovnikov Hydroetherification of Alkenols

(2012) David S. Hamilton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Practical and innate carbon–hydrogen functionalization of heterocycles

(2012) Yuta Fujiwara et al.   NATURE

‘One-pot’ synthesis of 4-substituted 1,5-diaryl-1H-pyrazole-3-carboxylates via lithium tert-butoxide-mediated sterically hindered Claisen condensation and Knorr reaction

(2012) Jian-An Jiang et al.   TETRAHEDRON

Modelling fundamental arene–borane contacts: spontaneous formation of a dibromoborenium cation driven by interaction between a borane Lewis acid and an arene π system

(2011) Hassanatu B. Mansaray et al.   CHEMICAL COMMUNICATIONS

Environment-Friendly Bromination of Aromatic Heterocycles Using a Bromide–Bromate Couple in an Aqueous Medium

(2011) Girdhar Joshi et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis

(2011) David A. Nagib et al.   NATURE

Consecutive Condensation, C–N and N–N Bond Formations: A Copper- Catalyzed One-Pot Three-Component Synthesis of 2H-Indazole

(2011) Manian Rajesh Kumar et al.   ORGANIC LETTERS

Direct Alkylation of Heteroaryls Using Potassium Alkyl- and Alkoxymethyltrifluoroborates

(2011) Gary A. Molander et al.   ORGANIC LETTERS

Innate C-H trifluoromethylation of heterocycles

(2011) Y. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trimethyl borate-induced one-pot homologation reactions of isoquinoline with di-tert-butyl-TMP zincate

(2011) Hye Ji Seo et al.   TETRAHEDRON LETTERS

Minisci reactions: Versatile CH-functionalizations for medicinal chemists

(2011) Matthew A. J. Duncton   MedChemComm

Aryl Trifluoroborates in Suzuki-Miyaura Coupling: The Roles of Endogenous Aryl Boronic Acid and Fluoride

(2010) Mike Butters et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxidation of Alkyl Trifluoroborates: An Opportunity for Tin-Free Radical Chemistry

(2010) Geoffroy Sorin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Privileged scaffolds for library design and drug discovery

(2010) Matthew E Welsch et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Direct C−H Arylation of Electron-Deficient Heterocycles with Arylboronic Acids

(2010) Ian B. Seiple et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cancer Therapies Utilizing the Camptothecins: A Review of thein VivoLiterature

(2010) Vincent J. Venditto et al.   MOLECULAR PHARMACEUTICS

7-Cycloalkylcamptothecin derivatives: Preparation and biological evaluation

(2009) Mingzong Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS