Tau directs intracellular trafficking by regulating the forces exerted by kinesin and dynein teams

Phosphoregulation of Tau modulates inhibition of kinesin-1 motility

(2017) Jamie L. Stern et al.   MOLECULAR BIOLOGY OF THE CELL

The axonal transport motor kinesin-2 navigates microtubule obstacles via protofilament switching

(2017) Gregory J. Hoeprich et al.   TRAFFIC

Tau and Aβ imaging, CSF measures, and cognition in Alzheimer’s disease

(2016) Matthew R. Brier et al.   Science Translational Medicine

The Mechanochemical Cycle of Mammalian Kinesin-2 KIF3A/B under Load

(2015) Johan O.L. Andreasson et al.   CURRENT BIOLOGY

Biophysical Challenges to Axonal Transport: Motor-Cargo Deficiencies and Neurodegeneration

(2014) Sandra E. Encalada et al.   Annual Review of Biophysics

Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity

(2014) Kristen E. Funk et al.   BIOCHEMICAL JOURNAL

Kinesin’s Neck-Linker Determines its Ability to Navigate Obstacles on the Microtubule Surface

(2014) Gregory J. Hoeprich et al.   BIOPHYSICAL JOURNAL

Tau interconverts between diffusive and stable populations on the microtubule surface in an isoform and lattice specific manner

(2014) Derrick P. McVicker et al.   Cytoskeleton

Molecular counting by photobleaching in protein complexes with many subunits: best practices and application to the cellulose synthesis complex

(2014) Yalei Chen et al.   MOLECULAR BIOLOGY OF THE CELL

Bidirectional cargo transport: moving beyond tug of war

(2014) William O. Hancock   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Integrated regulation of motor-driven organelle transport by scaffolding proteins

(2014) Meng-meng Fu et al.   TRENDS IN CELL BIOLOGY

The influence of dynein processivity control, MAPs, and microtubule ends on directional movement of a localising mRNA

(2014) Harish Chandra Soundararajan et al.   eLife

Molecular Adaptations Allow Dynein to Generate Large Collective Forces inside Cells

(2013) Arpan K. Rai et al.   CELL

In vivo optical trapping indicates kinesin’s stall force is reduced by dynein during intracellular transport

(2013) Benjamin H. Blehm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tau Protein Diffuses along the Microtubule Lattice

(2012) Maike H. Hinrichs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynein achieves processive motion using both stochastic and coordinated stepping

(2012) Weihong Qiu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors

(2012) A. G. Hendricks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tracking Single Particles and Elongated Filaments with Nanometer Precision

(2011) Felix Ruhnow et al.   BIOPHYSICAL JOURNAL

The Nucleotide-binding State of Microtubules Modulates Kinesin Processivity and the Ability of Tau to Inhibit Kinesin-mediated Transport

(2011) Derrick P. McVicker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport

(2011) Nicholas M. Kanaan et al.   NEUROBIOLOGY OF AGING

Post-translational modifications of tau protein: Implications for Alzheimer's disease

(2011) Ludovic Martin et al.   NEUROCHEMISTRY INTERNATIONAL

Cytoplasmic Dynein Moves Through Uncoordinated Stepping of the AAA+ Ring Domains

(2011) M. A. DeWitt et al.   SCIENCE

Motor Coordination via a Tug-of-War Mechanism Drives Bidirectional Vesicle Transport

(2010) Adam G. Hendricks et al.   CURRENT BIOLOGY

Retrograde axonal transport: pathways to cell death?

(2010) Eran Perlson et al.   TRENDS IN NEUROSCIENCES

Random Walk of Processive, Quantum Dot-Labeled Myosin Va Molecules within the Actin Cortex of COS-7 Cells

(2009) Shane R. Nelson et al.   BIOPHYSICAL JOURNAL

Opposite-polarity motors activate one another to trigger cargo transport in live cells

(2009) Shabeen Ally et al.   JOURNAL OF CELL BIOLOGY

Axonal Transport Defects in Neurodegenerative Diseases

(2009) G. A. Morfini et al.   JOURNAL OF NEUROSCIENCE

Kinesin superfamily motor proteins and intracellular transport

(2009) Nobutaka Hirokawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tug-of-war between dissimilar teams of microtubule motors regulates transport and fission of endosomes

(2009) V. Soppina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hyperphosphorylation of Microtubule-Associated Protein Tau: A Promising Therapeutic Target for Alzheimer Disease

(2008) C.-X. Gong et al.   CURRENT MEDICINAL CHEMISTRY

Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors

(2008) M. J. I. Muller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Regulation of Dynein and Kinesin Motor Proteins by Tau

(2008) R. Dixit et al.   SCIENCE

Tuning Microtubule-Based Transport Through Filamentous MAPs: The Problem of Dynein

(2008) Michael Vershinin et al.   TRAFFIC

Different Microtubule Motors Move Early and Late Endocytic Compartments

(2008) Sylvain Loubéry et al.   TRAFFIC

Identification of an Axonal Kinesin-3 Motor for Fast Anterograde Vesicle Transport that Facilitates Retrograde Transport of Neuropeptides

(2007) Rosemarie V. Barkus et al.   MOLECULAR BIOLOGY OF THE CELL