标题
Biophysical properties of the clinical-stage antibody landscape
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 114, Issue 5, Pages 944-949
出版商
Proceedings of the National Academy of Sciences
发表日期
2017-01-18
DOI
10.1073/pnas.1616408114
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Target-independent variable region mediated effects on antibody clearance can be FcRn independent
- (2016) Ryan L. Kelly et al. mAbs
- Developability Assessment During the Selection of Novel Therapeutic Antibodies
- (2015) Alexander Jarasch et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- An alternative assay to hydrophobic interaction chromatography for high-throughput characterization of monoclonal antibodies
- (2015) Patricia Estep et al. mAbs
- A novel screening method to assess developability of antibody-like molecules
- (2015) Neeraj Kohli et al. mAbs
- High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in mice
- (2015) Ryan L Kelly et al. mAbs
- The interplay of non-specific binding, target-mediated clearance and FcRn interactions on the pharmacokinetics of humanized antibodies
- (2015) Amita Datta-Mannan et al. mAbs
- Aggregation risk prediction for antibodies and its application to biotherapeutic development
- (2015) Olga Obrezanova et al. mAbs
- An analysis of the attrition of drug candidates from four major pharmaceutical companies
- (2015) Michael J. Waring et al. NATURE REVIEWS DRUG DISCOVERY
- Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics
- (2015) Angela Schoch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Plasmonic measurements of monoclonal antibody self-association using self-interaction nanoparticle spectroscopy
- (2014) Jayapriya Jayaraman et al. BIOTECHNOLOGY AND BIOENGINEERING
- Improving Monoclonal Antibody Selection and Engineering using Measurements of Colloidal Protein Interactions
- (2014) Steven B. Geng et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- In silico selection of therapeutic antibodies for development: Viscosity, clearance, and chemical stability
- (2014) Vikas K. Sharma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- High-throughput screening for developability during early-stage antibody discovery using self-interaction nanoparticle spectroscopy
- (2013) Yuqi Liu et al. mAbs
- High throughput detection of antibody self-interaction by bio-layer interferometry
- (2013) Tingwan Sun et al. mAbs
- Rapid Analysis of Antibody Self-Association in Complex Mixtures Using Immunogold Conjugates
- (2013) Shantanu V. Sule et al. MOLECULAR PHARMACEUTICS
- Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation
- (2013) Feng Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool
- (2013) Y. Xu et al. PROTEIN ENGINEERING DESIGN & SELECTION
- A strategy for risk mitigation of antibodies with fast clearance
- (2012) Isidro Hötzel et al. mAbs
- Solubility evaluation of murine hybridoma antibodies
- (2012) Stacey Spencer et al. mAbs
- High-Throughput Analysis of Concentration-Dependent Antibody Self-Association
- (2011) Shantanu V. Sule et al. BIOPHYSICAL JOURNAL
- Development of high concentration protein biopharmaceuticals: The use of platform approaches in formulation development
- (2011) Nicholas W. Warne EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Fc domain mediated self-association of an IgG1 monoclonal antibody under a low ionic strength condition
- (2011) Hirotaka Nishi et al. JOURNAL OF BIOSCIENCE AND BIOENGINEERING
- High‐Throughput Assessment of Thermal and Colloidal Stability Parameters for Monoclonal Antibody Formulations
- (2011) Feng He et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Developability Index: A Rapid In Silico Tool for the Screening of Antibody Aggregation Propensity
- (2011) Timothy M. Lauer et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation
- (2010) Hugo Mouquet et al. NATURE
- Cross-Interaction Chromatography: A Rapid Method to Identify Highly Soluble Monoclonal Antibody Candidates
- (2009) Steven A. Jacobs et al. PHARMACEUTICAL RESEARCH
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