A novel screening method to assess developability of antibody-like molecules

The effect of arginine glutamate on the stability of monoclonal antibodies in solution

(2014) Priscilla Kheddo et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Rapid optimization and prototyping for therapeutic antibody-like molecules

(2013) Lihui Xu et al.   mAbs

Developability studies before initiation of process development

(2013) Xiaoyu Yang et al.   mAbs

High-throughput screening for developability during early-stage antibody discovery using self-interaction nanoparticle spectroscopy

(2013) Yuqi Liu et al.   mAbs

Rapid Analysis of Antibody Self-Association in Complex Mixtures Using Immunogold Conjugates

(2013) Shantanu V. Sule et al.   MOLECULAR PHARMACEUTICS

Antibody Therapeutics in Cancer

(2013) M. X. Sliwkowski et al.   SCIENCE

Weak Interactions Govern the Viscosity of Concentrated Antibody Solutions: High-Throughput Analysis Using the Diffusion Interaction Parameter

(2012) Brian D. Connolly et al.   BIOPHYSICAL JOURNAL

Monoclonal antibody therapeutics: history and future

(2012) Nicholas APS Buss et al.   CURRENT OPINION IN PHARMACOLOGY

Solubility evaluation of murine hybridoma antibodies

(2012) Stacey Spencer et al.   mAbs

High Affinity, Developability and Functional Size: The Holy Grail of Combinatorial Antibody Library Generation

(2011) Dirk Ponsel et al.   MOLECULES

Single B cell antibody technologies

(2011) Thomas Tiller   New Biotechnology

Behavior of Monoclonal Antibodies: Relation Between the Second Virial Coefficient (B 2) at Low Concentrations and Aggregation Propensity and Viscosity at High Concentrations

(2011) Shuntaro Saito et al.   PHARMACEUTICAL RESEARCH

Formulation Development of Therapeutic Monoclonal Antibodies Using High-Throughput Fluorescence and Static Light Scattering Techniques: Role of Conformational and Colloidal Stability

(2010) Deborah S. Goldberg et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Prediction of Aggregation Prone Regions of Therapeutic Proteins

(2010) Naresh Chennamsetty et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Structural properties of monoclonal antibody aggregates induced by freeze–thawing and thermal stress

(2009) Andrea Hawe et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Specific interactions in high concentration antibody solutions resulting in high viscosity

(2009) Sandeep Yadav et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

High-Throughput Thermal Scanning: A General, Rapid Dye-Binding Thermal Shift Screen for Protein Engineering

(2009) Jason J. Lavinder et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cross-Interaction Chromatography: A Rapid Method to Identify Highly Soluble Monoclonal Antibody Candidates

(2009) Steven A. Jacobs et al.   PHARMACEUTICAL RESEARCH

Developability assessment in pharmaceutical industry: An integrated group approach for selecting developable candidates

(2008) Vishal Saxena et al.   JOURNAL OF PHARMACEUTICAL SCIENCES