Insights into the lifestyle of uncultured bacterial natural product factories associated with marine sponges

Polytheonamide biosynthesis showcasing the metabolic potential of sponge-associated uncultivated ‘Entotheonella’ bacteria

(2016) Michael F Freeman et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Increasing the Richness of Culturable Arsenic-Tolerant Bacteria from Theonella swinhoei by Addition of Sponge Skeleton to the Growth Medium

(2016) Ray Keren et al.   MICROBIAL ECOLOGY

Seven enzymes create extraordinary molecular complexity in an uncultivated bacterium

(2016) Michael F. Freeman et al.   Nature Chemistry

Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by ‘Entotheonella’

(2016) Yu Nakashima et al.   PLoS One

Teixobactin, the first of a new class of antibiotics discovered by iChip technology?

(2015) Laura J. V. Piddock   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A new antibiotic kills pathogens without detectable resistance

(2015) Losee L. Ling et al.   NATURE

Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms

(2015) Reiko Ueoka et al.   Nature Chemical Biology

KEGG as a reference resource for gene and protein annotation

(2015) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

The Pfam protein families database: towards a more sustainable future

(2015) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

The photochemical mechanism of a B12-dependent photoreceptor protein

(2015) Roger J. Kutta et al.   Nature Communications

Culturable associated-bacteria of the sponge Theonella swinhoei show tolerance to high arsenic concentrations

(2015) Ray Keren et al.   Frontiers in Microbiology

RadicalS-Adenosyl Methionine Epimerases: Regioselective Introduction of DiverseD-Amino Acid Patterns into Peptide Natural Products

(2014) Brandon I. Morinaka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PQQ-dependent methanol dehydrogenases: rare-earth elements make a difference

(2014) Jan T. Keltjens et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Molybdenum and tungsten-dependent formate dehydrogenases

(2014) Luisa B. Maia et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

An environmental bacterial taxon with a large and distinct metabolic repertoire

(2014) Micheal C. Wilson et al.   NATURE

Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont

(2014) Toshiyuki Wakimoto et al.   Nature Chemical Biology

UniProt: a hub for protein information

(2014)   NUCLEIC ACIDS RESEARCH

Metagenomic Approaches for Exploiting Uncultivated Bacteria as a Resource for Novel Biosynthetic Enzymology

(2013) Micheal C. Wilson et al.   CHEMISTRY & BIOLOGY

Rare earth metals are essential for methanotrophic life in volcanic mudpots

(2013) Arjan Pol et al.   ENVIRONMENTAL MICROBIOLOGY

Implementing sponge physiological and genomic information to enhance the diversity of its culturable associated bacteria

(2013) Adi Lavy et al.   FEMS MICROBIOLOGY ECOLOGY

MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0

(2013) Koichiro Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of Pathway/Genome Databases

(2013) Ron Caspi et al.   NUCLEIC ACIDS RESEARCH

Atmospheric deposition of methanol over the Atlantic Ocean

(2013) M. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic insights into the marine sponge microbiome

(2012) Ute Hentschel et al.   NATURE REVIEWS MICROBIOLOGY

TIGRFAMs and Genome Properties in 2013

(2012) Daniel H. Haft et al.   NUCLEIC ACIDS RESEARCH

Metagenome Mining Reveals Polytheonamides as Posttranslationally Modified Ribosomal Peptides

(2012) M. F. Freeman et al.   SCIENCE

IMG: the integrated microbial genomes database and comparative analysis system

(2011) V. M. Markowitz et al.   NUCLEIC ACIDS RESEARCH

Unexpected Abundance of Coenzyme F420-Dependent Enzymes in Mycobacterium tuberculosis and Other Actinobacteria

(2010) J. D. Selengut et al.   JOURNAL OF BACTERIOLOGY

CDD: a Conserved Domain Database for the functional annotation of proteins

(2010) A. Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Marine natural products

(2009) John W. Blunt et al.   NATURAL PRODUCT REPORTS

Community proteogenomics reveals insights into the physiology of phyllosphere bacteria

(2009) N. Delmotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of the bacterial symbiont Entotheonella sp. in the mesohyl of the marine sponge Discodermia sp.

(2008) Wolfram M Brück et al.   ISME Journal

An Improved General Amino Acid Replacement Matrix

(2008) S. Q. Le et al.   MOLECULAR BIOLOGY AND EVOLUTION

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY