Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy
出版年份 2017 全文链接
标题
Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 114, Issue 47, Pages 12448-12453
出版商
Proceedings of the National Academy of Sciences
发表日期
2017-11-07
DOI
10.1073/pnas.1707925114
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Treatment of Sarcopenia with Bimagrumab: Results from a Phase II, Randomized, Controlled, Proof-of-Concept Study
- (2017) Daniel Rooks et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease
- (2017) Justin L. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activin A more prominently regulates muscle mass in primates than does GDF8
- (2017) Esther Latres et al. Nature Communications
- Lack of evidence for GDF11 as a rejuvenator of aged skeletal muscle satellite cells
- (2016) Aaron C. Hinken et al. AGING CELL
- Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease
- (2016) Marissa J. Schafer et al. Cell Metabolism
- Myostatin inhibitor ACE-031 treatment of ambulatory boys with Duchenne muscular dystrophy: Results of a randomized, placebo-controlled clinical trial
- (2016) Craig Campbell et al. MUSCLE & NERVE
- ActRII blockade protects mice from cancer cachexia and prolongs survival in the presence of anti-cancer treatments
- (2016) Shinji Hatakeyama et al. Skeletal Muscle
- GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration
- (2015) Marc A. Egerman et al. Cell Metabolism
- Myostatin antibody (LY2495655) in older weak fallers: a proof-of-concept, randomised, phase 2 trial
- (2015) Clemens Becker et al. Lancet Diabetes & Endocrinology
- Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice
- (2015) Esther Latres et al. Skeletal Muscle
- Regulation and actions of activin A and follistatin in myocardial ischaemia–reperfusion injury
- (2014) Yi Chen et al. CYTOKINE
- Treatment of sporadic inclusion body myositis with bimagrumab
- (2014) A. A. Amato et al. NEUROLOGY
- G.P.205
- (2014) A. Mulivor et al. NEUROMUSCULAR DISORDERS
- Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle
- (2014) M. Sinha et al. SCIENCE
- Signaling pathways controlling skeletal muscle mass
- (2013) Marc A. Egerman et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Myostatin/activin pathway antagonism: Molecular basis and therapeutic potential
- (2013) H.Q. Han et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Disuse-induced muscle wasting
- (2013) Sue C. Bodine INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass
- (2013) Catherine E. Winbanks et al. JOURNAL OF CELL BIOLOGY
- An Antibody Blocking Activin Type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy
- (2013) E. Lach-Trifilieff et al. MOLECULAR AND CELLULAR BIOLOGY
- BMP signaling controls muscle mass
- (2013) Roberta Sartori et al. NATURE GENETICS
- Sarcopenia in the elderly
- (2012) J. E. Morley FAMILY PRACTICE
- A single ascending-dose study of muscle regulator ace-031 in healthy volunteers
- (2012) Kenneth M. Attie et al. MUSCLE & NERVE
- TAK-1/p38/nNFκB signaling inhibits myoblast differentiation by increasing levels of Activin A
- (2012) Anne Trendelenburg et al. Skeletal Muscle
- Recent advances in the biology and therapy of muscle wasting
- (2010) David Glass et al. Annals of the New York Academy of Sciences
- Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival
- (2010) Xiaolan Zhou et al. CELL
- Regulation of Muscle Mass by Follistatin and Activins
- (2010) Se-Jin Lee et al. MOLECULAR ENDOCRINOLOGY
- Akt Deficiency Attenuates Muscle Size and Function but Not the Response to ActRIIB Inhibition
- (2010) Marcus D. Goncalves et al. PLoS One
- Redundancy of myostatin and growth/differentiation factor 11 function
- (2009) Alexandra C McPherron et al. BMC DEVELOPMENTAL BIOLOGY
- Proteomic Identification and Functional Validation of Activins and Bone Morphogenetic Protein 11 as Candidate Novel Muscle Mass Regulators
- (2008) Tatyana A. Souza et al. MOLECULAR ENDOCRINOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started