Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice

Exercise Metabolism

(2015) Nikla Emambokus et al.   Cell Metabolism

GPR17 gene disruption does not alter food intake or glucose homeostasis in mice

(2015) Jason Mastaitis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Muscle wasting: An overview of recent developments in basic research

(2014) Sandra Palus et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes

(2014) L. E. Macdonald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice

(2014) A. J. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle

(2014) M. Sinha et al.   SCIENCE

Highlights from the 7th Cachexia Conference: muscle wasting pathophysiological detection and novel treatment strategies

(2014) Nicole Ebner et al.   Journal of Cachexia Sarcopenia and Muscle

Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy

(2013) Francesco S. Loffredo et al.   CELL

Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway

(2012) S.-J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Building muscle, browning fat and preventing obesity by inhibiting myostatin

(2011) N. K. LeBrasseur   DIABETOLOGIA

Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease

(2011) Liping Zhang et al.   FASEB JOURNAL

Acute antibody-directed myostatin inhibition attenuates disuse muscle atrophy and weakness in mice

(2011) Kate T. Murphy et al.   JOURNAL OF APPLIED PHYSIOLOGY

Myostatin deficiency is associated with an increase in number of total axons and motor axons innervating mouse tibialis anterior muscle

(2011) Stephanie Gay et al.   MUSCLE & NERVE

Genetic Deletion of Myostatin From the Heart Prevents Skeletal Muscle Atrophy in Heart Failure

(2010) Joerg Heineke et al.   CIRCULATION

Antibody-directed myostatin inhibition in 21-mo-old mice reveals novel roles for myostatin signaling in skeletal muscle structure and function

(2010) Kate T. Murphy et al.   FASEB JOURNAL

Postnatal PPARδ Activation and Myostatin Inhibition Exert Distinct yet Complimentary Effects on the Metabolic Profile of Obese Insulin-Resistant Mice

(2010) Barbara L. Bernardo et al.   PLoS One

Follistatin induces muscle hypertrophy through satellite cell proliferation and inhibition of both myostatin and activin

(2009) Hélène Gilson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A frameshift mutation in the coding region of themyostatingene (MSTN) affects carcass conformation and fatness in Norwegian White Sheep (Ovis aries)

(2009) I. A. Boman et al.   ANIMAL GENETICS

Myostatin Inhibition Enhances the Effects of Exercise on Performance and Metabolic Outcomes in Aged Mice

(2009) N. K. LeBrasseur et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Skeletal muscle gene expression after myostatin knockout in mature mice

(2009) Stephen Welle et al.   PHYSIOLOGICAL GENOMICS