Functional analysis of the zebrafish ortholog of HMGCS1 reveals independent functions for cholesterol and isoprenoids in craniofacial development

Inactivation of Geminin in neural crest cells affects the generation and maintenance of enteric progenitor cells, leading to enteric aganglionosis

(2016) Athanasia Stathopoulou et al.   DEVELOPMENTAL BIOLOGY

Cholesterol Biosynthesis Supports Myelin Gene Expression and Axon Ensheathment through Modulation of P13K/Akt/mTor Signaling

(2016) E. S. Mathews et al.   JOURNAL OF NEUROSCIENCE

RASopathies: unraveling mechanisms with animal models

(2015) G. A. Jindal et al.   Disease Models & Mechanisms

New insights into craniofacial malformations

(2015) Stephen R.F. Twigg et al.   HUMAN MOLECULAR GENETICS

Reduced cholesterol levels impair Smoothened activation in Smith–Lemli–Opitz syndrome

(2015) Robert Blassberg et al.   HUMAN MOLECULAR GENETICS

Sonic hedgehog multimerization: A self-organizing event driven by post-translational modifications?

(2015) Mirella V. Koleva et al.   MOLECULAR MEMBRANE BIOLOGY

Pathogenesis, epidemiology, diagnosis and clinical aspects of Smith–Lemli–Opitz syndrome

(2015) Simona E Bianconi et al.   Expert Opinion on Orphan Drugs

Hedgehog Cholesterolysis: Specialized Gatekeeper to Oncogenic Signaling

(2015) Brian Callahan et al.   Cancers

Protein Prenylation: Enzymes, Therapeutics, and Biotechnology Applications

(2014) Charuta C. Palsuledesai et al.   ACS Chemical Biology

The neural crest: A versatile organ system

(2014) Dongcheng Zhang et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Characterization of large deletions in theDHCR7gene

(2014) B. Lanthaler et al.   CLINICAL GENETICS

Hcfc1b, a zebrafish ortholog of HCFC1, regulates craniofacial development by modulating mmachc expression

(2014) Anita M. Quintana et al.   DEVELOPMENTAL BIOLOGY

Treacher Collins Syndrome: The genetics of a craniofacial disease

(2014) Sameep Kadakia et al.   INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY

Disrupting hedgehog and WNT signaling interactions promotes cleft lip pathogenesis

(2014) Hiroshi Kurosaka et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutation of 3-Hydroxy-3-Methylglutaryl CoA Synthase I Reveals Requirements for Isoprenoid and Cholesterol Synthesis in Oligodendrocyte Migration Arrest, Axon Wrapping, and Myelin Gene Expression

(2014) E. S. Mathews et al.   JOURNAL OF NEUROSCIENCE

Inactivation of Cdc42 in neural crest cells causes craniofacial and cardiovascular morphogenesis defects

(2013) Yang Liu et al.   DEVELOPMENTAL BIOLOGY

miR-219 Regulates Neural Precursor Differentiation by Direct Inhibition of Apical Par Polarity Proteins

(2013) Laura I. Hudish et al.   DEVELOPMENTAL CELL

Zebrafish etv7 regulates red blood cell development through the cholesterol synthesis pathway

(2013) A. M. Quintana et al.   Disease Models & Mechanisms

Signals and Switches in Mammalian Neural Crest Cell Differentiation

(2013) S. Bhatt et al.   Cold Spring Harbor Perspectives in Biology

Smith-Lemli-Opitz syndrome: Phenotype, natural history, and epidemiology

(2012) Małgorzata J.M. Nowaczyk et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Cholesterol synthesis-related enzyme oxidosqualene cyclase is required to maintain self-renewal in primary erythroid progenitors

(2011) C. Mejia-Pous et al.   CELL PROLIFERATION

Identification of an evolutionarily conserved regulatory element of the zebrafish col2a1a gene

(2011) Rodney M. Dale et al.   DEVELOPMENTAL BIOLOGY

Zebrafish con/disp1 reveals multiple spatiotemporal requirements for Hedgehog-signaling in craniofacial development

(2009) Tyler Schwend et al.   BMC DEVELOPMENTAL BIOLOGY

The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation

(2009) William E Tidyman et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Expression ofpatched, prdm1andengrailedin the lamprey somite reveals conserved responses to Hedgehog signaling

(2009) Katherine L. Hammond et al.   EVOLUTION & DEVELOPMENT

CNS-derived glia ensheath peripheral nerves and mediate motor root development

(2008) Sarah Kucenas et al.   NATURE NEUROSCIENCE

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols