Reduced cholesterol levels impair Smoothened activation in Smith–Lemli–Opitz syndrome
出版年份 2015 全文链接
标题
Reduced cholesterol levels impair Smoothened activation in Smith–Lemli–Opitz syndrome
作者
关键词
-
出版物
HUMAN MOLECULAR GENETICS
Volume 25, Issue 4, Pages 693-705
出版商
Oxford University Press (OUP)
发表日期
2015-12-31
DOI
10.1093/hmg/ddv507
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Variations in EEG discharges predict ADHD severity within individual Smith-Lemli-Opitz patients
- (2014) J. M. Schreiber et al. NEUROLOGY
- Hedgehog Pathway Modulation by Multiple Lipid Binding Sites on the Smoothened Effector of Signal Response
- (2013) Benjamin R. Myers et al. DEVELOPMENTAL CELL
- Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling
- (2013) Daniel Nedelcu et al. Nature Chemical Biology
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling
- (2013) Sigrid Nachtergaele et al. eLife
- 7-Dehydrocholesterol-derived oxysterols and retinal degeneration in a rat model of Smith–Lemli–Opitz syndrome
- (2012) Libin Xu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Oxysterols are allosteric activators of the oncoprotein Smoothened
- (2012) Sigrid Nachtergaele et al. Nature Chemical Biology
- Gli Proteins in Development and Disease
- (2011) Chi-chung Hui et al. Annual Review of Cell and Developmental Biology
- Gradients of signalling in the developing limb
- (2011) Matthew Towers et al. CURRENT OPINION IN CELL BIOLOGY
- Small molecule modulation of HH-GLI signaling: Current leads, trials and tribulations
- (2010) Christophe Mas et al. BIOCHEMICAL PHARMACOLOGY
- Malformation syndromes caused by disorders of cholesterol synthesis
- (2010) Forbes D. Porter et al. JOURNAL OF LIPID RESEARCH
- Antipsychotic Drugs Regulate Hedgehog Signaling by Modulation of 7-Dehydrocholesterol Reductase Levels
- (2010) M. Lauth et al. MOLECULAR PHARMACOLOGY
- The primary cilium: a signalling centre during vertebrate development
- (2010) Sarah C. Goetz et al. NATURE REVIEWS GENETICS
- Analysis of short-term behavioral effects of dietary cholesterol supplementation in Smith-Lemli-Opitz syndrome
- (2009) Elaine Tierney et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Patched regulates Smoothened trafficking using lipoprotein-derived lipids
- (2009) H. Khaliullina et al. DEVELOPMENT
- Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium
- (2009) Ljiljana Milenkovic et al. JOURNAL OF CELL BIOLOGY
- Effects of Dietary Cholesterol and Simvastatin on Cholesterol Synthesis in Smith-Lemli-Opitz Syndrome
- (2009) Yen-Ming Chan et al. PEDIATRIC RESEARCH
- Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation
- (2009) Yu Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hedgehog Signaling in Development and Cancer
- (2008) Jin Jiang et al. DEVELOPMENTAL CELL
- Smith–Lemli–Opitz syndrome: pathogenesis, diagnosis and management
- (2008) Forbes D Porter EUROPEAN JOURNAL OF HUMAN GENETICS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now