Bioluminescence Imaging of Spheroids for High-throughput Longitudinal Studies on 3D Cell Culture Models

Life is 3D: Boosting Spheroid Function for Tissue Engineering

(2017) Matthias W. Laschke et al.   TRENDS IN BIOTECHNOLOGY

Silk scaffolds connected with different naturally occurring biomaterials for prostate cancer cell cultivation in 3D

(2016) Anne Bäcker et al.   BIOPOLYMERS

Smart material platforms for miniaturized devices: implications in disease models and diagnostics

(2016) Ritika Verma et al.   LAB ON A CHIP

Screening out irrelevant cell-based models of disease

(2016) Peter Horvath et al.   NATURE REVIEWS DRUG DISCOVERY

Three-dimensional culture systems in cancer research: Focus on tumor spheroid model

(2016) Sritama Nath et al.   PHARMACOLOGY & THERAPEUTICS

A new orange emitting luciferase from the Southern-Amazon Pyrophorus angustus (Coleoptera: Elateridae) click-beetle: structure and bioluminescence color relationship, evolutional and ecological considerations

(2016) Danilo T. Amaral et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Direct Measurements of Oxygen Gradients in Spheroid Culture System Using Electron Parametric Resonance Oximetry

(2016) Laura M. Langan et al.   PLoS One

An enhanced chimeric firefly luciferase-inspired enzyme for ATP detection and bioluminescence reporter and imaging applications

(2015) Bruce R. Branchini et al.   ANALYTICAL BIOCHEMISTRY

High-Content Assays for Characterizing the Viability and Morphology of 3D Cancer Spheroid Cultures

(2015) Oksana Sirenko et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Simultaneous multicolor luciferase reporter assays for monitoring of multiple genes expressions

(2015) Yoshihiro Ohmiya   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Three-Dimensional Cell Culture: A Breakthrough in Vivo

(2015) Delphine Antoni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exploiting in vitro and in vivo bioluminescence for the implementation of the three Rs principle (replacement, reduction, and refinement) in drug discovery

(2014) Elisa Michelini et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Multicolor Bioluminescence Boosts Malaria Research: Quantitative Dual-Color Assay and Single-Cell Imaging in Plasmodium falciparum Parasites

(2014) Luca Cevenini et al.   ANALYTICAL CHEMISTRY

Multiplexing Spheroid Volume, Resazurin and Acid Phosphatase Viability Assays for High-Throughput Screening of Tumour Spheroids and Stem Cell Neurospheres

(2014) Delyan P. Ivanov et al.   PLoS One

Triple Bioluminescence Imaging for In Vivo Monitoring of Cellular Processes

(2013) Casey A Maguire et al.   Molecular Therapy-Nucleic Acids

An oxygen-permeable spheroid culture system for the prevention of central hypoxia and necrosis of spheroids

(2012) Takahisa Anada et al.   BIOMATERIALS

Firefly Luciferase in Chemical Biology: A Compendium of Inhibitors, Mechanistic Evaluation of Chemotypes, and Suggested Use As a Reporter

(2012) Natasha Thorne et al.   CHEMISTRY & BIOLOGY

Cell-based assays: fuelling drug discovery

(2010) Elisa Michelini et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Bioluminescence assays: multicolor luciferase assay, secreted luciferase assay and imaging luciferase assay

(2010) Yoshihiro Nakajima et al.   Expert Opinion on Drug Discovery

A sensitive recombinant cell-based bioluminescent assay for detection of androgen-like compounds

(2009) Elisa Michelini et al.   Nature Protocols

A Specific Mechanism for Nonspecific Activation in Reporter-Gene Assays

(2008) Douglas S. Auld et al.   ACS Chemical Biology