Aspects of Carbon Monoxide in Form of CO-Releasing Molecules Used in Cancer Treatment: More Light on the Way

Vascular and angiogenic activities of CORM-401, an oxidant-sensitive CO-releasing molecule

(2016) Sarah Fayad-Kobeissi et al.   BIOCHEMICAL PHARMACOLOGY

CO-releasing properties and anticancer activities of manganese complexes with imidazole/benzimidazole ligands

(2016) Elvan Üstün et al.   JOURNAL OF COORDINATION CHEMISTRY

Toward Carbon Monoxide–Based Therapeutics: Critical Drug Delivery and Developability Issues

(2016) Xingyue Ji et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Rapid Eradication of Human Breast Cancer Cells through Trackable Light-Triggered CO Delivery by Mesoporous Silica Nanoparticles Packed with a Designed photoCORM

(2015) Indranil Chakraborty et al.   CHEMISTRY OF MATERIALS

Transition-Metal-Free CO-Releasing BODIPY Derivatives Activatable by Visible to NIR Light as Promising Bioactive Molecules

(2015) Eduardo Palao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Folic acid-tagged protein nanoemulsions loaded with CORM-2 enhance the survival of mice bearing subcutaneous A20 lymphoma tumors

(2015) Ana Loureiro et al.   Nanomedicine-Nanotechnology Biology and Medicine

Carbon monoxide inhibits sprouting angiogenesis and vascular endothelial growth factor receptor-2 phosphorylation

(2015) Peter W. Hewett et al.   THROMBOSIS AND HAEMOSTASIS

Carbon monoxide: pro- or anti-angiogenic agent? Comment on Ahmad et al. (Thromb Haemost 2015; 113: 329–337)

(2015) Agnieszka Loboda et al.   THROMBOSIS AND HAEMOSTASIS

Synthesis, toxicities and cell proliferation inhibition of CO-releasing molecules containing cobalt

(2015) Yaguo Gong et al.   TRANSITION METAL CHEMISTRY

HO-1/CO system in tumor growth, angiogenesis and metabolism — Targeting HO-1 as an anti-tumor therapy

(2015) Agnieszka Loboda et al.   VASCULAR PHARMACOLOGY

Synthesis, Structural Characterization and Preliminary Biological Studies of Several Heterocyclic Transition Metal Carbonyl Complexes

(2015) Shanfang Hu et al.   ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE

Carbon-Monoxide-Releasing Molecules for the Delivery of Therapeutic CO In Vivo

(2014) Sandra García-Gallego et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel lead structures and activation mechanisms for CO-releasing molecules (CORMs)

(2014) U Schatzschneider   BRITISH JOURNAL OF PHARMACOLOGY

Antiproliferative effects of carbon monoxide on pancreatic cancer

(2014) Libor Vítek et al.   DIGESTIVE AND LIVER DISEASE

Synthesis and Characterization of a “Turn-On” photoCORM for Trackable CO Delivery to Biological Targets

(2014) Samantha J. Carrington et al.   ACS Medicinal Chemistry Letters

Interplay Between Heme Oxygenase-1 and miR-378 Affects Non-Small Cell Lung Carcinoma Growth, Vascularization, and Metastasis

(2013) Klaudia Skrzypek et al.   ANTIOXIDANTS & REDOX SIGNALING

CORM-3, a water soluble CO-releasing molecule, uncouples mitochondrial respiration via interaction with the phosphate carrier

(2013) Romain Long et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Carbon Monoxide Expedites Metabolic Exhaustion to Inhibit Tumor Growth

(2013) B. Wegiel et al.   CANCER RESEARCH

Rapid CO release from a Mn(i) carbonyl complex derived from azopyridine upon exposure to visible light and its phototoxicity toward malignant cells

(2013) Samantha J. Carrington et al.   CHEMICAL COMMUNICATIONS

CO and CO-releasing molecules in medicinal chemistry

(2013) Fabio Zobi   Future Medicinal Chemistry

Low concentration of exogenous carbon monoxide protects mammalian cells against proliferation induced by radiation-induced bystander effect

(2013) Liping Tong et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Visible-light activatable organic CO-releasing molecules (PhotoCORMs) that simultaneously generate fluorophores

(2013) Ping Peng et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The induction of heme oxygenase-1 suppresses heat shock protein 90 and the proliferation of human breast cancer cells through its byproduct carbon monoxide

(2013) Wen-Ying Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Developing drug molecules for therapy with carbon monoxide

(2012) Carlos C. Romão et al.   CHEMICAL SOCIETY REVIEWS

Carbon monoxide releasing molecule-2 CORM-2 represses global protein synthesis by inhibition of eukaryotic elongation factor eEF2

(2012) Christian Ingo Schwer et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Carbon monoxide: An unusual drug

(2012) Francesca Gullotta et al.   IUBMB LIFE

A Luminescent and Biocompatible PhotoCORM

(2012) Agustin E. Pierri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Generation of Carbon Monoxide Releasing Molecules (CO-RMs) as Drug Candidates for the Treatment of Acute Liver Injury: Targeting of CO-RMs to the Liver

(2012) Ana R. Marques et al.   ORGANOMETALLICS

Regulation of ROS Production and Vascular Function by Carbon Monoxide

(2012) Yoon Kyung Choi et al.   Oxidative Medicine and Cellular Longevity

Heme oxygenase 1 (HO-1) challenges the angiogenic switch in prostate cancer

(2011) M. Ferrando et al.   ANGIOGENESIS

Carbon monoxide, generated by heme oxygenase-1, mediates the enhanced permeability and retention effect in solid tumors

(2011) Jun Fang et al.   CANCER SCIENCE

Photochemically activated carbon monoxide release for biological targets. Toward developing air-stable photoCORMs labilized by visible light

(2011) R. Dale Rimmer et al.   COORDINATION CHEMISTRY REVIEWS

A carbon monoxide-releasing molecule (CORM-3) uncouples mitochondrial respiration and modulates the production of reactive oxygen species

(2011) Luisa Lo Iacono et al.   FREE RADICAL BIOLOGY AND MEDICINE

Synthesis, Characterization, and Reactivity of the Stable Iron Carbonyl Complex [Fe(CO)(N4Py)](ClO4)2: Photoactivated Carbon Monoxide Release, Growth Inhibitory Activity, and Peptide Ligation

(2011) Casey S. Jackson et al.   INORGANIC CHEMISTRY

Beneficial effects of carbon monoxide-releasing molecule-2 (CORM-2) on acute doxorubicin cardiotoxicity in mice: Role of oxidative stress and apoptosis

(2011) Hitesh Soni et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Carbon Monoxide Promotes VEGF Expression by Increasing HIF-1α Protein Level via Two Distinct Mechanisms, Translational Activation and Stabilization of HIF-1α Protein

(2010) Yoon Kyung Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The therapeutic potential of carbon monoxide

(2010) Roberto Motterlini et al.   NATURE REVIEWS DRUG DISCOVERY

Photoinduced CO release, cellular uptake and cytotoxicity of a tris(pyrazolyl)methane (tpm) manganese tricarbonyl complex

(2008) Johanna Niesel et al.   CHEMICAL COMMUNICATIONS

Heme Oxygenase-1 and Carbon Monoxide in Vascular Pathobiology

(2008) Jozef Dulak et al.   CIRCULATION

Use of carbon monoxide as a therapeutic agent: promises and challenges

(2008) Roberta Foresti et al.   INTENSIVE CARE MEDICINE

Heme oxygenase-1 inhibits breast cancer invasion via suppressing the expression of matrix metalloproteinase-9

(2008) C.-W. Lin et al.   MOLECULAR CANCER THERAPEUTICS

Physiological activities of carbon monoxide-releasing molecules: Ça ira

(2007) P K Chatterjee   BRITISH JOURNAL OF PHARMACOLOGY